P29 TOTAL LONGITUDINAL DISPLACEMENT (TLOD) OF THE COMMON CAROTID ARTERY (CCA) DOES NOT DIFFER BETWEEN PATIENTS WITH MODERATE OR HIGH CARDIOVASCULAR RISK (CV) AND PATIENTS AFTER ACUTE MYOCARDIAL INFARCTION (AMI)

2017 ◽  
Vol 20 (C) ◽  
pp. 101
Author(s):  
Urtė Gargalskaitė ◽  
Pranas Šerpytis ◽  
Karolis Azukaitis ◽  
Rokas Navickas ◽  
Vilma Dzenkeviciute ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Common Carotid Artery ◽  
Longitudinal Displacement ◽  
High Cardiovascular Risk ◽  
The Common

scholarly journals Risk of acute myocardial infarction among new users of chondroitin sulfate: A nested case-control study

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0253932
Author(s):  
Ramón Mazzucchelli ◽  
Sara Rodríguez-Martín ◽  
Alberto García-Vadillo ◽  
Miguel Gil ◽  
Antonio Rodríguez-Miguel ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cardiovascular Risk ◽  
Chondroitin Sulfate ◽  
Index Date ◽  
Case Control Study ◽  
Case Control ◽  
High Cardiovascular Risk ◽  
Incident Cases ◽  
Control Study

Objective To test the hypothesis that the use of chondroitin sulfate (CS) or glucosamine reduces the risk of acute myocardial infarction (AMI). Design Case-control study nested in a primary cohort of patients aged 40 to 99 years, using the database BIFAP during the 2002–2015 study period. From this cohort, we identified incident cases of AMI and randomly selected five controls per case, matched by exact age, gender, and index date. Adjusted odds ratios (AOR) and 95% confidence interval (CI) were computed through a conditional logistic regression. Only new users of CS or glucosamine were considered. Results A total of 23,585 incident cases of AMI and 117,405 controls were included. Of them, 89 cases (0.38%) and 757 controls (0.64%) were current users of CS at index date, yielding an AOR of 0.57 (95%CI: 0.46–0.72). The reduced risk among current users was observed in both short-term (<365 days, AOR = 0.58; 95%CI: 0.45–0.75) and long-term users (>364 days AOR = 0.56; 95%CI:0.36–0.87), in both sexes (men, AOR = 0.52; 95%CI:0.38–0.70; women, AOR = 0.65; 95%CI:0.46–0.91), in individuals over or under 70 years of age (AOR = 0.54; 95%CI:0.38–0.77, and AOR = 0.61; 95%CI:0.45–0.82, respectively) and in individuals at intermediate (AOR = 0.65; 95%CI:0.48–0.91) and high cardiovascular risk (AOR = 0.48; 95%CI:0.27–0.83), but not in those at low risk (AOR = 1.11; 95%CI:0.48–2.56). In contrast, the current use of glucosamine was not associated with either increased or decreased risk of AMI (AOR = 0.86; 95%CI:0.66–1.08). Conclusions Our results support a cardioprotective effect of CS, while glucosamine seems to be neutral. The protection was remarkable among subgroups at high cardiovascular risk.

P3400Definition of extremely high cardiovascular risk in patients after acute myocardial infarction - Data from the TERCET Registry

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
K Dyrbus ◽  
M Gasior ◽  
P Desperak ◽  
T Osadnik ◽  
M Banach
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Multivariate Analysis ◽  
Cardiovascular Risk ◽  
High Risk ◽  
Density Lipoprotein ◽  
Cardiovascular Prevention ◽  
Risk Category ◽  
High Cardiovascular Risk

Abstract Background The latest guidelines from the American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE) introduced a new “ultra-high risk” category of patients, for whom a low-density lipoprotein cholesterol (LDL-C) level <55 mg/dL (1.4 mmol/L) is advised. Purpose Therefore we aimed at identification of the risk factors in patients after acute myocardial infarction (MI), which increased the risk most, and might help to define the group of individuals at extremely high cardiovascular (CV) risk. Methods We analyzed consecutive patients included in the TERCET Registry admitted to the Polish tertiary cardiovascular centre due to MI between 2006 and 2018. According to the guidelines of the European Society of Cardiology (ESC), all patients included in the analysis are considered as of very high CV risk. All patients included in the registry underwent coronary angiography during the hospital stay. On the basis of multivariate analysis, we determined the subgroup of patients with the most unfavourable 12-month outcome (all-cause mortality). Results Finally, 4,562 patients admitted due to STEMI or NSTEMI and discharged from our centre were included in the analysis. According to the results of multivariate analysis performed with stepwise backward regression model, the following risk factors in patients after MI: LVEF<35% (odds ratio [OR]=3.83, 95% confidence interval [CI]: 3.14–4.67), age>75 years (OR=1.91, 95% CI: 1.55–2.35), lack of PCI of culprit vessel (OR=1.66, 95% CI: 1.26–2.20), multivessel CAD (OR=1.60, 95% CI: 1.30–1.99), atrial fibrillation (OR=1.53, 95% CI: 1.21–1.94), diabetes mellitus (OR=1.34, 95% CI: 1.11–1.64), increased LDL-C level (OR=1.09 per 1 mmol/L, 95% CI: 1.01–1.19) and increased creatinine level (OR=1.04 per 10 μmol/L, 95% CI: 1.04–1.05), might help to define the group of patients at extremely-high cardiovascular risk (all p<0.05). The aggregate summary of risk factors associated with extremely high risk is presented in the attached Figure. Next, the effect of the combination of the aforementioned risk factors will be investigated, and SCORE applied for patients in secondary prevention after MI will be prepared. Multivariate analysis results Conclusions To our knowledge, the presented study is the first such an analysis conducted on the population of patients after myocardial infarction gathered in the registry of secondary cardiovascular prevention. In patients after MI, potential risk factors were identified that might help to define the group of patients at ultra-high/extremely-high risk, what might contribute to significantly higher 12-month mortality. Acknowledgement/Funding None

Influence of cardiovascular risk factors on longitudinal motion of the common carotid artery wall

2018 ◽  
Vol 272 ◽  
pp. 54-59 ◽  
Author(s):  
S. Helena Taivainen ◽  
Heikki Yli-Ollila ◽  
Markus Juonala ◽  
Mika Kähönen ◽  
Olli T. Raitakari ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Common Carotid Artery ◽  
Longitudinal Motion ◽  
Artery Wall ◽  
Carotid Artery Wall ◽  
The Common

Normal values for intima-media thickness of the common carotid artery - an update following a novel risk factor profiling

VASA ◽  
2015 ◽  
Vol 44 (6) ◽  
pp. 444-450 ◽  
Author(s):  
Elko Randrianarisoa ◽  
Roderich Rietig ◽  
Stephan Jacob ◽  
Gunnar Blumenstock ◽  
Hans-Ulrich Haering ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Common Carotid Artery ◽  
Normal Values ◽  
Intima Media Thickness ◽  
Age And Gender ◽  
The Common ◽  
And Gender ◽  
Gender Specific

Abstract. Background: There is a widely approved influence of novel risk factors like the body fat distribution and the associated metabolic syndrome, subclinical inflammation, insulin resistance and prediabetic disturbances in glucose metabolism on the progression of atherosclerosis. Former studies examining normal values for intima-media thickness (IMT) did not consider all of these new study results in detail. We therefore aimed to assess an update on age- and gender-specific normal values for IMT accounting for these novel risk factors. Patients and methods: We evaluated IMT by high-resolution ultrasound (13 MHz) on the far wall of the common carotid artery in 801 subjects without cardiovascular disease (428 women aged 46.2±12.9 years; 373 men aged 47.3±13.3 years). After precise evaluation and exclusion of 14 cardiovascular risk factors, 90% limits of IMT were determined by parametric statistics. Results: The reference limits of IMT according to the age classes 18-29, 30-39, 40-49 and 50-59 years were estimated as 0.47, 0.59, 0.67 and 0.70 mm in women and 0.47, 0.62, 0.72 and 0.80 mm in men. Conclusions: Age and gender-specific normal values for IMT are lower than reported in former studies after additionally accounting for novel cardiovascular risk factors. The still widely regarded upper IMT limit of 1 mm must be strictly regarded as obsolete.

Sign in / Sign up

Export Citation Format

Share Document