q-Rung orthopair fuzzy sets (q-ROFSs), originally proposed by Yager, can powerfully modify the range of indication of decision information by changing a parameter q based on the different hesitation degree, and the dual hesitant q-rung orthopair fuzzy set (DHq-ROFS), a new technique to consider human’s hesitance, can be more substantial of dealing with real multi-attribute decision making (MADM) problems. Inspired by DHq-ROFSs, in this article, we extend the concept of q-rung orthopair fuzzy graphs to dual hesitant q-rung orthopair fuzzy context and introduce the innovative concept of a dual hesitant q-rung orthopair fuzzy graphs based on Hamacher operator called dual hesitant q-rung orthopair fuzzy Hamacher graphs (DHq-ROFHGs). We propose the new concepts of geometric-arithmetic energy and atom bond connectivity energy of a DHq-ROFHG and determine its upper and lower bounds. Moreover, on the basis of the proposed concept of DHq-ROFHGs, we introduce a new approach to solve the MADM problems with dual hesitant q-rung orthopair fuzzy information. At the end, we give a numerical model related to the selection of most significant defensive factor to illustrate the applicability of the developed approach, and exhibit its viability. Comparative analysis is conducted and the superiorities are illustrated.