Validation of a predictive model for identifying an increased risk for recurrence in adolescents and young adults with a first provoked thromboembolism

2022 ◽  
pp. 102651
Author(s):  
Verena Limperger ◽  
Antje Torge ◽  
Bettina Kiesau ◽  
Florian Langer ◽  
Gili Kenet ◽  
...  
Keyword(s):  
Young Adults ◽  
Predictive Model ◽  
Adolescents And Young Adults ◽  
Increased Risk

Epidemiological Trends in Attempted Suicide in Adolescents and Young Adults Between 1996 and 2004

Crisis ◽  
2009 ◽  
Vol 30 (3) ◽  
pp. 115-119 ◽  
Author(s):  
Stephanie De Munck ◽  
Gwendolyn Portzky ◽  
Kees Van Heeringen
Keyword(s):  
Young Adults ◽  
Attempted Suicide ◽  
Suicide Attempts ◽  
Epidemiological Studies ◽  
Adolescents And Young Adults ◽  
University Hospital ◽  
International Studies ◽  
Suicide Attempters ◽  
Increased Risk ◽  
Epidemiological Trends

Background: Notwithstanding the epidemiological studies indicating an increased risk of attempted suicide among adolescents and young adults, there is a scarcity of international studies that examine long-term epidemiological trends in rates and characteristics of this vulnerable group. Aims: This article describes the results of a 9-year monitoring study of suicide attempts in adolescents and young adults referred to the Accident and Emergency Department of the Gent University Hospital (Belgium). Methods: Between January 1996 and December 2004, trends, sociodemographic, and methodrelated characteristics of suicide attempts were assessed by a psychiatrist on data sheets. Results: Attempted suicide rates declined from 1996 to 2001 and then rose until 2004, but did not exceed previous rates. During the 9 years of monitoring, there was a preponderance of female suicide attempters, except for 1997. Rates of attempts and of fatal suicide were negatively correlated. Significantly more males than females deliberately injured themselves. Younger attempters, especially females, significantly more often poisoned themselves with analgesics. In nearly one in five attempts, alcohol was used in combination with other methods, and alcohol intake was more commonly observed in older suicide attempters. Nearly half of the adolescents were identified as repeaters. Conclusions: The results of this study warrant further monitoring of trends and characteristics of young suicide attempters.

scholarly journals Prevalence and heritability of body dysmorphic symptoms in adolescents and young adults: a population-based nationwide twin study

2018 ◽  
Vol 48 (16) ◽  
pp. 2740-2747 ◽  
Author(s):  
Jesper Enander ◽  
Volen Z. Ivanov ◽  
David Mataix-Cols ◽  
Ralf Kuja-Halkola ◽  
Brjánn Ljótsson ◽  
...  
Keyword(s):  
Young Adults ◽  
Body Dysmorphic Disorder ◽  
Age Of Onset ◽  
Model Fitting ◽  
Population Based ◽  
Adolescents And Young Adults ◽  
Shared Environment ◽  
Increased Risk ◽  
Clinically Significant ◽  
Alcohol Related Problems

AbstractBackgroundBody dysmorphic disorder (BDD) usually begins during adolescence but little is known about the prevalence, etiology, and patterns of comorbidity in this age group. We investigated the prevalence of BDD symptoms in adolescents and young adults. We also report on the relative importance of genetic and environmental influences on BDD symptoms, and the risk for co-existing psychopathology.MethodsPrevalence of BDD symptoms was determined by a validated cut-off on the Dysmorphic Concerns Questionnaire (DCQ) in three population-based twin cohorts at ages 15 (n = 6968), 18 (n = 3738), and 20–28 (n = 4671). Heritability analysis was performed using univariate model-fitting for the DCQ. The risk for co-existing psychopathology was expressed as odds ratios (OR).ResultsThe prevalence of clinically significant BDD symptoms was estimated to be between 1 and 2% in the different cohorts, with a significantly higher prevalence in females (1.3–3.3%) than in males (0.2–0.6%). The heritability of body dysmorphic concerns was estimated to be 49% (95% CI 38–54%) at age 15, 39% (95% CI 30–46) at age 18, and 37% (95% CI 29–42) at ages 20–28, with the remaining variance being due to non-shared environment. ORs for co-existing neuropsychiatric and alcohol-related problems ranged from 2.3 to 13.2.ConclusionsClinically significant BDD symptoms are relatively common in adolescence and young adulthood, particularly in females. The low occurrence of BDD symptoms in adolescent boys may indicate sex differences in age of onset and/or etiological mechanisms. BDD symptoms are moderately heritable in young people and associated with an increased risk for co-existing neuropsychiatric and alcohol-related problems.

scholarly journals Trends and gender differences in age at sex debut among adolescents and young adults in urban Cape Area, South Africa

1970 ◽  
Vol 19 (4) ◽  
pp. 2964-2972
Author(s):  
Evans Muchiri ◽  
Clifford Odimegwu
Keyword(s):  
Risk Factors ◽  
South Africa ◽  
Gender Differences ◽  
Young Adults ◽  
Sexual Debut ◽  
Adolescents And Young Adults ◽  
Community Factors ◽  
Contextual Risk ◽  
Increased Risk ◽  
And Gender

Background: Adolescents and young adults in South Africa are at increased risk of experiencing negative outcomes from early sex initiation due to the context they develop in. This study aimed at investigating trends and gender differences in early age at sexual debut.Methods: Data from the Cape Area Panel Study (CAPS) of young adults’ conducted between 2002 and 2009 in urban Cape Town were used. Correlates of early sex using ecological risk factors were analysed. Results: Overall mean age at sexual debut at follow-up was 17.5 years (standard deviation (SD) =2.5), with males at 16.8 years (SD=2.5) and 18.1 years (SD=2.4) for females. Males consistently reported an earlier age at sex debut across the five waves of the survey. Significant risk factors for early sex appeared at all levels of the ecology to include individual, household, and community factors. Conclusions: Integrated interventions for delaying early sex debut should consider factors within the ecology of the young adults’ development context.Keywords: Sex debut, adolescents and young adults, contextual risk factors, cumulative risk.

scholarly journals Increased risk of second malignant neoplasms in adolescents and young adults with cancer

Cancer ◽  
2015 ◽  
Vol 122 (1) ◽  
pp. 116-123 ◽  
Author(s):  
Jean S. Lee ◽  
Steven G. DuBois ◽  
Peter F. Coccia ◽  
Archie Bleyer ◽  
Rebecca L. Olin ◽  
...  
Keyword(s):  
Young Adults ◽  
Adolescents And Young Adults ◽  
Malignant Neoplasms ◽  
Increased Risk ◽  
Second Malignant Neoplasms

Cotard's syndrome in adolescents and young adults is associated with an increased risk of bipolar disorder

2007 ◽  
Vol 9 (6) ◽  
pp. 665-668 ◽  
Author(s):  
Angèle Consoli ◽  
Charlotte Soultanian ◽  
Marie-Laure Tanguy ◽  
Claudine Laurent ◽  
Didier Perisse ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Young Adults ◽  
Adolescents And Young Adults ◽  
Increased Risk

scholarly journals Anticoagulation treatment and prophylactic edoxaban for cerebral sinus venous thrombosis in an adolescent with acute lymphoblastic leukemia

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110132
Author(s):  
Masaya Koganesawa ◽  
Ryosuke Matsuno ◽  
Yumiko Sugishita ◽  
Ryota Kaneko ◽  
Naoko Kawabata ◽  
...  
Keyword(s):  
Young Adults ◽  
Acute Lymphoblastic Leukemia ◽  
Venous Thrombosis ◽  
Induction Therapy ◽  
Lymphoblastic Leukemia ◽  
Adolescents And Young Adults ◽  
Increased Risk ◽  
Cerebral Sinus Venous Thrombosis ◽  
Cerebral Sinus ◽  
Sinus Venous Thrombosis

Pediatric acute lymphoblastic leukemia regimens include large L-asparaginase dosages and steroids, which are associated with an increased risk of venous thromboemboli in adolescents and young adults. Herein, we report the case of an 18-year-old male with acute lymphoblastic leukemia, who was treated with the pediatric regimen, in which edoxaban was employed as a prophylaxis against cerebral sinus venous thrombosis. The event happened on day 20 of induction therapy, when brain magnetic resonance imaging demonstrated a cerebral sinus venous thrombosis in the superior sagittal sinus. Anticoagulation therapy was initiated, and the patient’s symptoms disappeared 3 days later. The induction therapy was restarted after an interruption of 16 days, and the consolidation therapies, which included L-asparaginase and steroids, were completed. Edoxaban was administered as a prophylaxis during the consolidation therapy. There were no further adverse events. Edoxaban could be an effective prophylaxis for coagulation complications in adolescents and young adults with acute lymphoblastic leukemia.

scholarly journals Coronavirus Disease 2019 Emergency and Remote Eye Movement Desensitization and Reprocessing Group Therapy With Adolescents and Young Adults: Overcoming Lockdown With the Butterfly Hug

2021 ◽  
Vol 12 ◽  
Author(s):  
Elisa Lazzaroni ◽  
Roberta Invernizzi ◽  
Elisa Fogliato ◽  
Marco Pagani ◽  
Giada Maslovaric
Keyword(s):  
Young Adults ◽  
Eye Movement ◽  
Self Report ◽  
Adolescents And Young Adults ◽  
Clinical Population ◽  
Event Scale ◽  
Increased Risk ◽  
Post Traumatic ◽  
The Impact ◽  
Traumatic Symptoms

The coronavirus disease 2019 (COVID-19) pandemic has represented an individual and collective trauma with an impact on mental health. Restrictive measures such as lockdowns have increased risk factors for the development or triggering of various psychopathologies. Timely psychological intervention has constituted a protective factor that has been indicated as a form of prevention. The main objective of this study was to measure changes in the levels of traumatic stress and anxiety in a clinical population of adolescents and young adults aged 13 to 24 years – already assisted by the local primary and specialty care services before the pandemic – following a trauma-focused psychotherapeutic group intervention according to the eye movement desensitization and reprocessing protocol, conducted remotely before the end of the first lockdown. The Impact of Event Scale-Revised (IES-R), State-Trait Anxiety Inventory (STAI) scales, and the Emotion Thermometer were administered pre- and post-treatment. At the end of the treatment, the Post-Traumatic Growth Inventory (PTGI) questionnaire was administered. The results show that there was a significant improvement pre- and post-intervention in the scores of the scales STAI, IES-R, and Emotion Thermometer with a reduction in post-traumatic symptoms related in particular to the domains of intrusiveness and hyperarousal. The domain of avoidance was less significantly modified by therapy. This overall clinical improvement did not correlate with any of the demographic variables of the sample. In addition, the results show a significant positive global perceived change (PTGI) that did not correlate with the reduction of anxiety or post-traumatic symptoms measured by the other self-report scales. The explored use of telemedicine has revealed a valuable clinical opportunity.

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