Staging of osteonecrosis of the jaw requires computed tomography for accurate definition of the extent of bony disease

Six patients with biopsy-proven hepatoma were prospectively evaluated both by conventional computed tomography (CT) and by scans using ethiodized oil emulsion 13 (EOE 13) as a contrast agent. EOE 13 infusion resulted in marked improvement in the demonstration of the neoplasm in all cases and allowed more accurate definition of tumor extent than was possible with standard scanning techniques. In two cases EOE 13 enhancement was essential for complete radiographic depiction of tumor location, size, and extent. EOE 13 also proved to be of considerable value in assessment of therapeutic response in three patients, permitting more objective determination of tumor growth or regression. EOE 13--enhanced CT scanning provides a valuable means of staging patients presenting with hepatoma and is a reliable, accurate means of radiographic follow-up.

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Frontal sinus and nasoethmoidal injuries

10.1093/med/9780199682874.003.0077 ◽

2021 ◽

pp. 821-826

Author(s):

Nabeela Ahmed ◽

Lachlan M. Carter ◽

Rabindra P. Singh

Keyword(s):

Computed Tomography ◽

High Resolution ◽

Frontal Sinus ◽

Critical Area ◽

Associated Injuries ◽

High Resolution Computed Tomography ◽

Accurate Definition ◽

Computed Tomography Scanning ◽

Definition Of ◽

Tomography Scanning

The frontal sinus and the adjacent naso-orbitoethmoid complex of bones in the midline are vulnerable to direct trauma and significant injuries can involve the adjacent skull base, the nasofrontal duct, and the medial orbit. The anatomy of this critical area is complex. Assessment of the injury includes ocular and neurological examination for associated injuries, and high-resolution computed tomography scanning is required for accurate definition of the injury. In this chapter, the principles of management and the complications of these fractures and their management are described.

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Imaging modalities in medication-related osteonecrosis of the jaw

Clinical and Laboratorial Research in Dentistry ◽

10.11606/issn.2357-8041.clrd.2020.164723 ◽

2020 ◽

Author(s):

Wellington Hideaki Yanaguizawa ◽

Solange Kobayashi Velasco ◽

Rodrigo Lima Petersen ◽

Fábio De Abreu Alves ◽

Marcelo Gusmão Paraíso Cavalcanti

Keyword(s):

Magnetic Resonance Imaging ◽

Computed Tomography ◽

Magnetic Resonance ◽

External Factor ◽

Panoramic Radiography ◽

Bone Destruction ◽

Osteonecrosis Of The Jaw ◽

Loss Of Function ◽

Resonance Imaging ◽

Definition Of

Osteonecrosis occurs by cellular death of the bone tissue due to an irreversible external factor. This disorder may be clinically unidentified in the early stages and result in degradation of the bone architectural structure, leading to pain, bone destruction, and loss of function. Thus, imaging exams become relevant to the recognition and definition of the bone necroses. The aim of this study was to review the literature on imaging exams frequently used for the diagnosis and evaluation of patients undergoing drug therapies associated with osteonecrosis of the jaw, such as panoramic radiography, computed tomography, magnetic resonance imaging and bone scintigraphy.

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Resolution and measurement in the scanning electron microscope

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100127256 ◽

1987 ◽

Vol 45 ◽

pp. 534-537 ◽

Cited By ~ 2

Author(s):

Michael T. Postek

Keyword(s):

Electron Microscope ◽

Scanning Electron Microscope ◽

Engineering Design ◽

Resolving Power ◽

Practical Applications ◽

Instrument Resolution ◽

Accurate Definition ◽

Definition Of ◽

Scanning Electron ◽

Better Than

The term ultimate resolution or resolving power is the very best performance that can be obtained from a scanning electron microscope (SEM) given the optimum instrumental conditions and sample. However, as it relates to SEM users, the conventional definitions of this figure are ambiguous. The numbers quoted for the resolution of an instrument are not only theoretically derived, but are also verified through the direct measurement of images on micrographs. However, the samples commonly used for this purpose are specifically optimized for the measurement of instrument resolution and are most often not typical of the sample used in practical applications.SEM RESOLUTION. Some instruments resolve better than others either due to engineering design or other reasons. There is no definitively accurate definition of how to quantify instrument resolution and its measurement in the SEM.

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Dasein, personeidad, intersubjetividad y persona-núcleo. El sujeto relacional después de Heidegger, en Zubiri, Apel y Polo. Dasein, Personhood, Inter-subjectivity and Nucleus-Person. The Relational Subject after Heidegger, in Zubiri, Apel and Polo

Metafísica y persona ◽

10.24310/metyper.2015.v0i13.2721 ◽

2017 ◽

Author(s):

Carlos Ortiz de Landázuri

Keyword(s):

Heuristic Strategies ◽

Accurate Definition ◽

Being There ◽

Definition Of

Heidegger, Zubiri, Apel y Polo habrían propuesto una definición más correcta de las respectivas nociones de sujeto relacional humano, a saber: “Dasein” o “ser-ahí”; “personeidad” o “esencia abierta”; “intersubjetividad” o “la llamada por parte de los entes a diversos interlocutores”; y, finalmente, “persona-núcleo” o “agente mediador entre los entes y el ser”. Se pretendía así evitar una vuelta a las paradojas del “sujeto transcendental” en Kant, del “yo absoluto” en Hegel o del “sujeto fenomenológico” en Husserl. Sin embargo en cada caso se siguieron estrategias heurísticas específicamente distintas a la hora de conceptualizar dicho sujeto relacional: Heidegger propuso una superación de la noción de “sujeto fenomenológico” en Husserl; Zubiri, en cambio, defendería una recuperación de la noción de “sujeto fenomenológico” en Husserl; por su parte, Apel propondría una reformulación semióticamente transformada del “Dasein” heideggeriano; finalmente, Polo propondría una reformulación gnoseológica de la noción de “Dasein” heideggeriano.Heidegger, Zubiri, Apel, and Polo have proposed a more accurate definition of the respective notions of human relational subject: “Dasein” or “being-there”; “Personhood” or “open essence”; “inter-subjectivity” or “entities’ appeal to diverse interlocutors”; and, finally, “nucleus-person” or “mediator between entities and being”. The aim is to avoid a return to Kant’s transcendental subject paradoxes and Hegel’s “absolute I” or Husserl´s “fenomenological subject”. But in each case specifically different heuristic strategies were followed when conceptualizing said relational subject: Heidegger proposed overcoming the notion of “phenomenological subject” in Husserl; Zubiri, however, defend the recovery of the notion of “phenomenological subject” in Husserl; meanwhile, Apel propose a transformed semiotically reformulation of Heidegger’s “Dasein”; finally, Polo propose a reformulation of the epistemological notion of Heidegger’s “Dasein”.

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Advancing UK Regulatory Science Strategy in the Context of Global Regulation: a Stakeholder Survey

Therapeutic Innovation & Regulatory Science ◽

10.1007/s43441-021-00263-2 ◽

2021 ◽

Author(s):

Samantha Cruz Rivera ◽

Barbara Torlinska ◽

Eliot Marston ◽

Alastair K. Denniston ◽

Kathy Oliver ◽

...

Keyword(s):

Pay For Performance ◽

Regulatory Science ◽

International Strategy ◽

Free Text ◽

The European Union ◽

Accurate Definition ◽

Definition Of ◽

Healthcare Innovation ◽

The Uk ◽

Medium Enterprises

Abstract Background The UK’s transition from the European Union creates both an urgent need and key opportunity for the UK and its global collaborators to consider new approaches to the regulation of emerging technologies, underpinned by regulatory science. This survey aimed to identify the most accurate definition of regulatory science, to define strategic areas of the regulation of healthcare innovation which can be informed through regulatory science and to explore the training and infrastructure needed to advance UK and international regulatory science. Methods A survey was distributed to UK healthcare professionals, academics, patients, health technology assessment agencies, ethicists and trade associations, as well as international regulators, pharmaceutical companies and small or medium enterprises which have expertise in regulatory science and in developing or applying regulation in healthcare. Subsequently, a descriptive quantitative analyses of survey results and directed thematic analysis of free-text comments were applied. Results Priority areas for UK regulatory science identified by 145 participants included the following: flexibility: the capability of regulations to adapt to novel products and target patient outcomes; co-development: collaboration across sectors, e.g. patients, manufacturers, regulators, and educators working together to develop appropriate training for novel product deployment; responsiveness: the preparation of frameworks which enable timely innovation required by emerging events; speed: the rate at which new products can reach the market; reimbursement: developing effective tools to track and evaluate outcomes for “pay for performance” products; and education and professional development. Conclusions The UK has a time-critical opportunity to establish its national and international strategy for regulatory science leadership by harnessing broader academic input, developing strategic cross-sector collaborations, incorporating patients’ experiences and perspectives, and investing in a skilled workforce.

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Cervical cytologic abnormalities and negative colposcopy: histologic assessment

International Journal of Gynecological Cancer ◽

10.1046/j.1525-1438.1994.04050348.x ◽

1994 ◽

Vol 4 (5) ◽

pp. 348-351 ◽

Cited By ~ 4

Author(s):

R. Chenoy ◽

S. Manohar ◽

C. W.E. Redman ◽

D. M. Luesley

Keyword(s):

Cervical Cytology ◽

Histologic Diagnosis ◽

Abnormal Cervical Cytology ◽

Accurate Definition ◽

Cone Biopsy ◽

Histologic Evaluation ◽

Simple Regression Analysis ◽

Definition Of ◽

Cytologic Abnormalities ◽

Intraepithelial Lesions

Colposcopic assessment may be normal in the presence of severe or persistent minor cytologic abnormality. To assess the significance of negative satisfactory colposcopy in patients with abnormal cervical smears, a retrospective review was carried out on 1170 patients who had undergone out-patient loop diathermy excision for abnormal cervical cytology. Of these, 69 patients were treated for abnormal cervical cytology, despite normal colposcopic findings. Cytologic abnormalities ranged from persistent borderline changes to severe dyskariosis. Histologic assessment of the excision specimens revealed cervical intraepithalial neoplasia (CIN) in 43 (62.3%) cases, of which high-grade CIN accounted for 24 (34.8%) cases. There was good correlation between cytologic and histologic diagnosis. Simple regression analysis showedr= 0.46,P< 0.0001. The cytologic abnormality was highly predictive of the corresponding histologic diagnosis. This analysis has shown that significant intraepithelial lesions may exist despite negative colposcopic examination and highlights the need for histologic evaluation in such cases. In these circumstances, loop cone biopsy permits accurate definition of lesion severity, avoids potential undertreatment of significant lesions and causes less morbidity than conventional cone biopsy.

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Theism and Hypertheism

Harvard Theological Review ◽

10.1017/s0017816000029096 ◽

1943 ◽

Vol 36 (1) ◽

pp. 63-81

Author(s):

John Laird

Keyword(s):

Accurate Definition ◽

Definition Of

Theists, I suppose, are persons who believe in “God's” existence. Atheists are persons who deny the same.Such statements may be suitable, and even adequate, for many proper purposes. In several contexts it is silly or malicious to interrogate them closely. Even in theology, which is, or should be, some kind of science, they may have, and they do have, their use and their propriety. For many theological purposes, however (and also for some others) they are far too vague. It may be wrong, no doubt, to tell a theologian that he must either produce an accurate definition of what he means by “God” or be forever shamed.

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Role of magnetic resonance ventriculography in multiloculated hydrocephalus

Journal of Neurosurgery Pediatrics ◽

10.3171/2013.2.peds12456 ◽

2013 ◽

Vol 11 (6) ◽

pp. 697-703 ◽

Cited By ~ 12

Author(s):

Gurpreet S. Gandhoke ◽

Paolo Frassanito ◽

Nagesh Chandra ◽

Bal K. Ojha ◽

Anoop Singh

Keyword(s):

Magnetic Resonance ◽

Endoscopic Treatment ◽

Ventricular System ◽

Third Ventriculostomy ◽

Csf Flow ◽

Reliable Technique ◽

Accurate Definition ◽

Multiloculated Hydrocephalus ◽

Definition Of ◽

Complex Cases

Object In this paper the authors' goal was to investigate the clinical usefulness of Gd-enhanced MR ventriculography (MRV) in pediatric patients affected by multiloculated hydrocephalus. Methods Eighteen patients (11 boys and 7 girls, age range 2–14 months) with a diagnosis of multiloculated hydrocephalus were included in the study. After injection of gadodiamide (0.02–0.04 mmol) into the lateral ventricle by tapping the anterior fontanel, sagittal, coronal, and axial T1-weighted MR images were acquired. The location of the septations and the sites of obstruction of CSF flow were assessed. Postoperative MRV was obtained to confirm the results of endoscopic treatment in most complex cases. Results No adverse events were observed after injection of contrast medium into the ventricular system. Preoperative MRV accurately defined the exact morphology of septae and ventricular walls in all cases. In 1 case the diagnosis of multiloculated hydrocephalus was ruled out. Sites of obstruction of CSF flow within the ventricular system were also well established. In 4 cases the multiple compartments were proven to intercommunicate. Postoperative MRV was useful in assessing the functional status of third ventriculostomy, aqueductoplasty, and other endoscopic fenestrations. Conclusions Magnetic resonance ventriculography is a safe, effective, and reliable technique. The accurate definition of the anatomy of the ventricles and the site of obstruction in multiloculated hydrocephalus can help to plan the most appropriate treatment and minimize the number of procedures. Although MRV is also useful during postoperative follow-up to determine the results of endoscopic treatment, it should be limited to particularly complex cases, due to its invasiveness.

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