Causes of fragility fractures of the proximal femur

Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S208
Author(s):  
K.E.S. Poole
2019 ◽  
Vol 41 (4) ◽  
pp. 518-525
Author(s):  
Aída Fernanda Batista Rocha ◽  
Marcus Villander Barros De Oliveira Sá ◽  
Ubirace Fernando Elihimas Junior

ABSTRACT Introduction: Proximal femur fractures affect the mortality and morbidity of elderly individuals. Recent studies have shown an association between fragility fractures and hyponatremia, a common fluid and electrolyte balance disorder. Objectives: This study aimed to investigate the occurrence of hyponatremia in patients with fragility fractures of the proximal femur. Methods: The authors looked into the data from the medical records of patients admitted to the emergency unit of the Real Hospital Português for fragility fractures of the proximal femur from 2014 to 2017. The study included patients with serum sodium levels recorded in their charts. Results: Fourteen of 69 (20.3%) patients with proximal femur fractures had hyponatremia. The main factors linked to hyponatremia were lung disease, and prescription of amiodarone and/or antidepressants. Conclusion: In elderly individuals, fragility fractures of the proximal femur may correlate with hyponatremia, particularly among patients on amiodarone or antidepressants.


2013 ◽  
Vol 14 (1) ◽  
Author(s):  
Yaogang Lu ◽  
Lei Wang ◽  
Yongqiang Hao ◽  
Ziping Wang ◽  
Minghui Wang ◽  
...  

2020 ◽  
pp. 4696-4702
Author(s):  
Nicholas C. Harvey ◽  
Juliet Compston ◽  
Cyrus Cooper

Osteoporosis is characterized by a reduction in bone mass and disruption of bone architecture, resulting in increased bone fragility and fracture risk, with fractures of the distal radius (Colles’ fracture), spine, and proximal femur being most characteristic. One in two women and one in five men over the age of 50 years will suffer an osteoporotic fracture during their remaining lifetime, with massive cost to healthcare services. Osteoporotic fractures are termed fragility fractures (defined as occurring after a fall from standing height or less). They may occur at several skeletal sites but fractures of the distal radius (Colles’ fracture), spine, and proximal femur are most characteristic. The incidence of osteoporotic fractures increases markedly with age; in women, the median age for Colles’ fractures is 65 years and for hip fracture, 80 years.


2015 ◽  
Vol 26 (8) ◽  
pp. 2137-2146 ◽  
Author(s):  
L. A. Ahmed ◽  
R. Shigdel ◽  
R. M. Joakimsen ◽  
O. P. Eldevik ◽  
E. F. Eriksen ◽  
...  

Author(s):  
Ilaria Morelli ◽  
Francesco Luceri ◽  
Riccardo Giorgino ◽  
Riccardo Accetta ◽  
Paolo Perazzo ◽  
...  

2006 ◽  
Vol 9 (2) ◽  
pp. 6-12
Author(s):  
L Ya ROZhINSKAYa ◽  
S D ARAPOVA ◽  
L K DZERANOVA ◽  
N N MOLITVOSLOVOVA ◽  
A V IL'IN ◽  
...  

The aims of the reported multinational open study were to estimate the influence of subcutaneous injections of 20 mkg daily Teriparatide on bone mineral density (BMD) at the lumbar spine and proximal femur, the markers of bone metabolism, the quality of life as well as the safety of treatment. Duration of the treatment period was one year. Fifty postmenopausal women with osteoporosis (L1-L4 T-score mean -3,2±0,6 SD) were enrolled in the study. 70,8% of patients had fragility fractures. Forty four patients (78%) remained until the end of the study. BMD was detected by dual energy X-ray absorptiometry (DXA) («Prodigy», Lunar and «Hologic» 4500 W) at the lumbar spine (L1-L4) and proximal femur with converting to the standardized BMD. Bone alkaline phosphatase (BAP) and osteocalcin (OC) were measured as markers of bone formation and C-terminal cross-linking telopeptide (CTX) were measured in serum as a marker of bone resorption. The significant increase in BMD was found at the lumbar spine (L1-L412,5±6,6%), whereas BMD at the proximal femur did not change significantly. The levels of markers of bone metabolism were increased after 3 months of the treatment and to the end of the study were 192,2%; 385%; 526,3% higher versus the baseline levels for BAP, OC., CTX consequently. There was also found a significant improvement in the quality of life of the patients which was estimated by EQ-5D inquirer at the baseline visit and at the end of the study. The adverse effects, which were related to the teriparatide injections, were observed in 44% of the patients. Due to the adverse effects Tereiparatide was cancelled for 6 (12%) patients. In other cases the adverse effects were slight and the cancellation of treatment was not required. Conclusions: The daily injections of Teriparatide (20 mkg) during 1 year provide the significant increase in BMD at the lumbar spine for postmenopausal women with osteoporosis as well as the early increase in the bone turnover rate. Treatment with Teriparatide improves the quality of life for women with postmenopausal osteoporosis. The daily injections of Teriparatide during 1 year are well tolerated and safe.


2007 ◽  
Vol 89 (5) ◽  
pp. 504-509 ◽  
Author(s):  
MF Nixon ◽  
T Ibrahim ◽  
Y Johari ◽  
S Eltayef ◽  
D Hariharan ◽  
...  

INTRODUCTION The incidence of fragility fractures could double in the next 50 years. Effective treatments for osteoporosis exist and the British Orthopaedic Association (BOA) has guidelines governing how to manage underlying osteoporosis in patients with fragility fractures. This study assessed how well two trauma units treat underlying osteoporosis and whether the BOA guidelines made any impact. PATIENTS AND METHODS Case notes of patients with a fracture of their proximal femur admitted during January and February in 2003, 2004 and 2005 were reviewed. The results were analysed for differences between site and year. RESULTS A total of 602 case notes were reviewed. There was a significant difference in the number of patients discharged on osteoporosis medication between the two sites (27% at LRI, 8% at KGH; P < 0.001), but not between 2003 and 2005 (22% and 16%; P = 0.16). Of the patients started on treatment, 83% were started on calcium and/or vitamin D3 supplements. CONCLUSIONS The number of patients who had their underlying osteoporosis addressed was low and the type of treatment sub-optimal. This suggests the BOA guidelines have not made an impact and further work is required to improve the management of these patients.


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