Modulatory role of grape seed extract on age-related oxidative DNA damage in central nervous system of rats

2006 ◽  
Vol 68 (6) ◽  
pp. 469-473 ◽  
Author(s):  
Muthaiya Balu ◽  
Purushotham Sangeetha ◽  
Ganesan Murali ◽  
Chinnakannu Panneerselvam
2005 ◽  
Vol 383 (3) ◽  
pp. 295-300 ◽  
Author(s):  
Muthaiya Balu ◽  
Purushotham Sangeetha ◽  
Dayalan Haripriya ◽  
Chinnakannu Panneerselvam

Author(s):  
Souad El Gengaihi ◽  
Doha H. Abou Baker

Interest in the biological role of bioactive compounds present in medicinal herbs has increased over the last years. Of particular interest are plants that have an anti-Alzheimer activities. Several plants can be useful for Alzheimer (AD) management. Such as these which have anti-inflammatory activity, acetylcholinesterase (AChE) inhibitory action, antiapoptotic, slow the aggregation of amyloid peptide and antioxidant activities. Grape seed extract (GSE) is a complex mixture of several compounds, mostly represented by polyphenols and flavonoids. Their consumption is safe and is recognized to exert several health benefits. GS flavonoids have been associated with the reduced risk of chronic diseases, we present some findings on the potential benefits of GSE for the treatment of AD.


2011 ◽  
Vol 8 (1) ◽  
pp. 39-45 ◽  
Author(s):  
Fulya Benzer ◽  
Fatih Mehmet Kandemir ◽  
Songul Ceribasi ◽  
Mustafa Ozkaraca ◽  
Nuran Cikcikoglu Yildirim ◽  
...  

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1501
Author(s):  
Julia Kaźmierczak-Barańska ◽  
Karolina Boguszewska ◽  
Angelika Adamus-Grabicka ◽  
Bolesław T. Karwowski

Vitamin C has been known for decades. It is common in everyday use as an element of the diet, supplementation, and a preservative. For years, research has been conducted to precisely determine the mechanism of action of ascorbate in the cell. Available results indicate its multi-directional cellular effects. Vitamin C, which belongs to antioxidants scavenging free radicals, also has a ‘second face’—as a pro-oxidative factor. However, whether is the latter nature a defect harmful to the cell, or whether a virtue that is a source of benefit? In this review, we discuss the effects of vitamin C treatment in cancer prevention and the role of ascorbate in maintaining redox balance in the central nervous system (CNS). Finally, we discuss the effect of vitamin C supplementation on biomarkers of oxidative DNA damage and review the evidence that vitamin C has radioprotective properties.


2015 ◽  
Vol 3 (7) ◽  
pp. 392-402
Author(s):  
Maurizio Fracchiolla ◽  
Mark McKenna ◽  
Kaisa Zaman ◽  
Patrick Becker ◽  
Thomas Terraz

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