Applying a novel statistical method to advance the personalized treatment of anxiety disorders: A composite moderator of comparative drop-out from CBT and ACT

2017 ◽  
Vol 91 ◽  
pp. 13-23 ◽  
Author(s):  
Andrea N. Niles ◽  
Kate B. Wolitzky-Taylor ◽  
Joanna J. Arch ◽  
Michelle G. Craske
2019 ◽  
Vol 9 (2) ◽  
pp. 53-67
Author(s):  
Pablo Herrera ◽  
Illia Mstibovskyi ◽  
Jan Roubal ◽  
Philip Brownell

Despite the proven efficacy of CBT treatments for anxiety disorders, between 33 % and 50 % of patients do not respond or drop out of these treatments. Gestalt therapy has claimed to be an effective alternative, but there is little empirical evidence on its efficacy with anxiety. The Single-Case Experimental Design with Time Series Analysis was used as a practice-oriented study of efficacy. Evidence on ten clients diagnosed with anxiety disorders is presented, supporting the claim that Gestalt therapy can be a useful treatment for this. Detailed analysis of one case illustrates the changes in symptom and well-being scores, indicating turning points during the therapy. The paper discusses the use of this methodology for creating a practice-oriented research network.


Author(s):  
Ata Ghaderi ◽  
Ingvar Rosendahl ◽  
Benjamin Bohman

Abstract Background: A substantial proportion of patients receiving cognitive behavioural therapy (CBT) do not achieve remission, and drop-out is considerable. Motivational interviewing (MI) may influence non-response and drop-out. Previous research shows that MI as a pre-treatment to CBT produces moderate effects compared with CBT alone. Studies integrating MI with CBT (MI-CBT) are scarce. Aims: To test the feasibility of MI-CBT in terms of therapist competence in MI and various participant measures, including recruitment and retention. In addition, separate preliminary evaluations were conducted, exploring the effects of CBT alone for anxiety disorders and depression, and of MI-CBT for anxiety disorders, depression and unhealthy lifestyle behaviours. Method: Using a randomised controlled parallel trial design, participants were recruited in routine psychiatric care and allocated to CBT alone or MI-CBT. Means in feasibility measures and within-condition Hedges’ g effect sizes in treatment outcome measures were calculated. Authors were not blind to treatment allocation, while independent raters were blind. Results: Seventy-three patients were assessed for eligibility, and 49 were included. Participant perceptions of treatment credibility, expectancy for improvement, and working alliance were similar for both conditions. Overall, effect sizes were large across outcome measures for both conditions, including anxiety and depressive symptoms and functional impairment. However, therapists did not acquire sufficient competence in MI and the drop-out rate was high. Conclusions: MI-CBT proved feasible in some respects, but the present study did not support the progression to a randomised controlled trial designed to assess the effectiveness of MI-CBT. Additional pilot studies are needed.


2010 ◽  
Vol 40 (12) ◽  
pp. 1943-1957 ◽  
Author(s):  
P. Cuijpers ◽  
T. Donker ◽  
A. van Straten ◽  
J. Li ◽  
G. Andersson

BackgroundAlthough guided self-help for depression and anxiety disorders has been examined in many studies, it is not clear whether it is equally effective as face-to-face treatments.MethodWe conducted a meta-analysis of randomized controlled trials in which the effects of guided self-help on depression and anxiety were compared directly with face-to-face psychotherapies for depression and anxiety disorders. A systematic search in bibliographical databases (PubMed, PsycINFO, EMBASE, Cochrane) resulted in 21 studies with 810 participants.ResultsThe overall effect size indicating the difference between guided self-help and face-to-face psychotherapy at post-test was d=−0.02, in favour of guided self-help. At follow-up (up to 1 year) no significant difference was found either. No significant difference was found between the drop-out rates in the two treatments formats.ConclusionsIt seems safe to conclude that guided self-help and face-to-face treatments can have comparable effects. It is time to start thinking about implementation in routine care.


2020 ◽  
Vol 11 (1) ◽  
pp. 127-130
Author(s):  
Arthi Chinna Meyyappan

Given the vast personal and economic burdens of psychiatric disorders, specifically mood and anxiety disorders, finding appropriate treatments for all those affected is critical. Due to the various presentations of psychiatric indications, no one treatment method is efficacious in all patients. Thus, a more personalized, but feasible treatment method is necessary for properly treating and preventing these disorders from becoming refractory and more burdensome. In recent years, there has been a growing appreciation for research in the field of the “gut-brain axis” (GBA), specifically as a target for psychiatric disorders. Researchers have found the gut to be influenced not only by similar determinants to that of psychiatric indications, but also highly modifiable using GBA treatments such as probiotics and fecal microbiota transplant (FMT). This is compelling evidence for the use of the GBA as a target for disorders such as depression and anxiety and for development of personalized treatment methods.


2015 ◽  
Vol 63 (2) ◽  
pp. 117-124 ◽  
Author(s):  
Max Böckermann ◽  
Annika Gieselmann ◽  
Marjolijn Sorbi ◽  
Reinhard Pietrowsky
Keyword(s):  
Drop Out ◽  

Hintergrund: Dieser Artikel beschreibt die Entwicklung eines internetbasierten begleiteten Selbsthilfetrainings (Albtraumcoach) zur Bewältigung von Albträumen, das innerhalb zweier Pilotstudien auf seine Durchführbarkeit und Anwendbarkeit getestet wurde. Methoden: Innerhalb eines neunstufigen Modells wird die Entwicklung der Intervention beschrieben. Dabei wird neben der wissenschaftlichen Evidenz, die die Basis für die Intervention bildet, auf technische, ethische, datenschutzrechtliche und weitere spezifische Maßnahmen innerhalb der Interventionsentwicklung eingegangen. In zwei Pilotstudien evaluierten zudem 10 Personen mit schlechten Träumen in der Vergangenheit die Durchführbarkeit (Studie 1) und 12 Personen mit wiederkehrenden Albträumen die Anwendbarkeit sowie den Nutzen der Intervention (Studie 2). Abhängige Variablen waren die Qualität der einzelnen Sitzungen, die Zufriedenheit mit der Intervention sowie Albtraumfrequenz, Albtraumbelastung, Schlafqualität und Depressivität. Ergebnisse und Diskussion: Die Durchführbarkeit und Anwendbarkeit des Trainings wurden positiv beurteilt. Während die Drop-out-Rate verhältnismäßig hoch war, ergaben sich erste, zurückhaltend zu beurteilende, Hinweise für einen Nutzen der Intervention.


Author(s):  
Stephanie Kunz ◽  
Michael Schulz ◽  
Gabriele Syrbe ◽  
Martin Driessen

<B>Fragestellung:</B> Lässt die wissenschaftliche Datenlage positive Behandlungseffekte durch Ohrakupunktur in der Entzugsbehandlung von Alkohol- und Opiatabhängigen erwarten? </P><P> <B>Methodik:</B> Die im Rahmen der Recherche gefundenen Studien bezogen sich auf den Entzug von Alkohol (sechs) und von Kokain und Opiaten (acht). Die Studien wurden auf ihre methodische Qualität hin überprüft. </P><P> <B>Ergebnisse:</B> Es konnten 14 randomisierte kontrollierte Studien (RCT) zu Ohrakupunktur in der Behandlung von Alkohol- und Opiatabhängigkeit identifiziert werden. Dabei weisen die meisten Studien methodische Mängel auf. Ein Vergleich der Studien ist aufgrund unterschiedlicher Paradigmen kaum möglich, die Drop Out Rate liegt häufig über 20%. </P><P> <B>Schlussfolgerung:</B> Insgesamt reicht die verfügbare wissenschaftliche Datenlage nicht aus, um eine positive Wirkung der Akupunktur bei substanzbezogenen Störungen als gesichert anzunehmen.


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