scholarly journals Reduction in heart failure admissions with concomitant respiratory viral infections during the novel coronavirus disease-2019 pandemic: Unintended consequence of public health measures in Singapore

2021 ◽  
Vol 27 (1) ◽  
pp. 117-119
Author(s):  
Liang EN Wee ◽  
Edwin Philip Conceicao ◽  
Jing Yuan Tan ◽  
Laura Li-Hua Chan ◽  
Poh Choo Phoon ◽  
...  
Thorax ◽  
2020 ◽  
pp. thoraxjnl-2020-216083
Author(s):  
Jing Yuan Tan ◽  
Edwin Philip Conceicao ◽  
Liang En Wee ◽  
Xiang Ying Jean Sim ◽  
Indumathi Venkatachalam

Hospitalisations for acute exacerbations of COPD (AECOPD) carry significant morbidity and mortality. Respiratory viral infections (RVIs) are the most common cause of AECOPD and are associated with worse clinical outcomes. During the COVID-19 pandemic, public health measures, such as social distancing and universal masking, were originally implemented to reduce transmission of SARS-CoV-2; these public health measures were subsequently also observed to reduce transmission of other common circulating RVIs. In this study, we report a significant and sustained decrease in hospital admissions for all AECOPD as well as RVI-associated AECOPD, which coincided with the introduction of public health measures during the COVID-19 pandemic.


2020 ◽  
Vol 5 (3) ◽  
Author(s):  
Muneeba Azmat

The pandemic of the 2019 novel Coronavirus has seen unprecedented exponential growth. Within three months, 192 countries have been affected, crossing more than 1 million confirmed cases and over 60 thousand deaths until the first week of April. Decision making in such a pandemic becomes difficult due to limited data on the nature of the disease and its propagation, course, prevention, and treatment. The pandemic response has varied from country to country and has resulted in a heterogeneous timeline for novel Coronavirus propagation. We compared the public health measures taken by various countries and the potential impact on the spread. We studied 6 countries including China, Italy, South Korea, Singapore, United Kingdom(UK), United States(US), and the special administrative region of Hong Kong. All articles, press releases, and websites of government entities published over a five-month period were included. A comparison of the date of the first diagnosed case, the spread of disease, and time since the first case and major public health policy implemented for prevention and containment and current cases was done. An emphasis on early and aggressive border restriction and surveillance of travelers from infected areas, use of information technology, and social distancing is necessary for control of the novel pandemic. Moving forwards, improvement in infrastructure, and adequate preparedness for pandemics is required.


2020 ◽  
Vol 21 ◽  
pp. 100329 ◽  
Author(s):  
Huai-liang Wu ◽  
Jian Huang ◽  
Casper J.P. Zhang ◽  
Zonglin He ◽  
Wai-Kit Ming

2020 ◽  
Vol 27 (2) ◽  
Author(s):  
A Wilder-Smith ◽  
D O Freedman

Public health measures were decisive in controlling the SARS epidemic in 2003. Isolation is the separation of ill persons from non-infected persons. Quarantine is movement restriction, often with fever surveillance, of contacts when it is not evident whether they have been infected but are not yet symptomatic or have not been infected. Community containment includes measures that range from increasing social distancing to community-wide quarantine. Whether these measures will be sufficient to control 2019-nCoV depends on addressing some unanswered questions.


2021 ◽  
Vol 23 (3) ◽  
pp. 296-303
Author(s):  
Dmitry I. Trukhan ◽  
◽  
Natalya V. Bagisheva ◽  
Anna V. Mordyk ◽  
Ekaterina Yu. Nebesnaya ◽  
...  

The modern approach to the prevention and treatment of acute respiratory viral infections consists in the use of drugs that increase the body’s defenses, helping to create a barrier to the penetration of the virus. Immunomodulators exhibit a nonspecific effect in acute respiratory viral infections, which makes it possible to use them against various types of respiratory viruses without accurate laboratory diagnostics and expands clinical capabilities. In the first part of the review, the features of sodium aminodihydrophthalazinedione and the experience of its use in respiratory pathology are considered. The pandemic of the novel coronavirus infection (COVID-19), spread by the novel coronavirus SARS-CoV-2, has become a challenge to health systems around the world. The second part of the review reviews the results of the first studies on the use of sodium aminodihydrophthalazinedione for the prevention and treatment of new coronavirus infection. Recently, much attention has been paid to the long-term consequences of the postponed coronavirus infection. In the final part of the review, various aspects of the “post-COVID syndrome” are discussed and the possibilities of aminodihydrophthalazinedione sodium at the stage of rehabilitation after a coronavirus infection are discussed.


2020 ◽  
Vol 106 (2) ◽  
pp. 387-389 ◽  
Author(s):  
J.Y. Tan ◽  
E.P. Conceicao ◽  
X.Y.J. Sim ◽  
L.E.I. Wee ◽  
M.K. Aung ◽  
...  

2021 ◽  
Vol 9 ◽  
Author(s):  
Enahoro Iboi ◽  
Ariana Richardson ◽  
Rachel Ruffin ◽  
DeAndrea Ingram ◽  
Jailyn Clark ◽  
...  

The coronavirus outbreak in the United States continues to pose a serious threat to human lives. Public health measures to slow down the spread of the virus involve using a face mask, social-distancing, and frequent hand washing. Since the beginning of the pandemic, there has been a global campaign on the use of non-pharmaceutical interventions (NPIs) to curtail the spread of the virus. However, the number of cases, mortality, and hospitalization continue to rise globally, including in the United States. We developed a mathematical model to assess the impact of a public health education program on the coronavirus outbreak in the United States. Our simulation showed the prospect of an effective public health education program in reducing both the cumulative and daily mortality of the novel coronavirus. Finally, our result suggests the need to obey public health measures as loss of willingness would increase the cumulative and daily mortality in the United States.


2021 ◽  
Author(s):  
Jennifer Y So ◽  
Nathan N O'Hara ◽  
Blaine Kenaa ◽  
John G Williams ◽  
Christopher L DeBorja ◽  
...  

Background: The COVID-19 pandemic has led to widespread implementation of public health measures, such as stay-at-home orders, social distancing, and masking mandates. In addition to decreasing spread of SARS-CoV2, these measures also impact the transmission of seasonal viral pathogens, which are common triggers of COPD exacerbations. Whether reduced viral prevalence mediates reduction in COPD exacerbation rates is unknown. Methods: We performed retrospective analysis of data from a large, multicenter healthcare system to assess admission trends associated with community viral prevalence and with initiation of COVID-19 pandemic control measures. We applied difference-in-differences (DiD) analysis to compare season-matched weekly frequency of hospital admissions for COPD before and after implementation of public health measures for COVID-19. Community viral prevalence was estimated using regional Center for Disease Control and Prevention test positivity data and correlated to COPD admissions. Results: Data involving 4,422 COPD admissions demonstrated a season-matched 53% decline in COPD admissions during COVID-19 pandemic, which correlated to community viral burden (r=0.73; 95% CI: 0.67 to 0.78) and represented a 36% greater decline over admission frequencies observed in other medical conditions less affected by respiratory viral infections (IRR, 0.64; 95% CI, 0.57 to 0.71, p<0.001). The post-COVID-19 decline in COPD admissions was most pronounced in patients with fewer comorbidities and without recurrent admissions. Conclusion: The implementation of public health measures during the COVID-19 pandemic was associated with decreased COPD admissions. These changes are plausibly explained by reduced prevalence of seasonal respiratory viruses.


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