Superolateral Hoffa's Fat Pad Edema and Trochlear Sulcal Angle Are Associated with Isolated Medial Patellofemoral Compartment Osteoarthritis

2018 ◽  
Vol 69 (4) ◽  
pp. 450-457 ◽  
Author(s):  
Sara Weintraub ◽  
Ronnie Sebro

Purpose To evaluate whether mediopatellar plica and knee morphometric measurements obtained from magnetic resonance imaging (MRI) studies are associated with isolated medial patellofemoral osteoarthritis in young adults. Methods MRI studies from 60 patients with isolated medial patellofemoral osteoarthritis and 90 control patients with normal knee MRI studies were reviewed. The presence of mediopatellar plica, the presence of edema in the superolateral aspect of Hoffa's fat pad and suprapatellar fat pad, quadriceps and patellar tendinosis, and axial and sagittal alignment of the patellar and trochlear morphology were assessed using MRI. The relationship between mediopatellar plica, alignment, or morphology and the presence of isolated medial patellofemoral osteoarthritis was evaluated using logistic regression. Results Superolateral Hoffa's fat pad edema (odds ratio [OR] = 3.4, P = .009) and decreased trochlear sulcal angle (OR = 0.95, P = .045) were associated with increased odds of isolated medial patellofemoral osteoarthritis. Decreased lateral patellar tilt (OR = 0.93, P = .087) and patellar tendinosis (OR = 4.13, P = .103) trended toward being associated with increased odds of isolated medial patellofemoral osteoarthritis but were not statistically significant. No significant association was seen between the presence of mediopatellar plica and medial patellofemoral osteoarthritis (OR = 0.95, P = .353). Conclusions Medial patellofemoral osteoarthritis is associated with trochlear morphology and patellar alignment but not with mediopatellar plica.

2021 ◽  
pp. 197140092199896
Author(s):  
Ahmed Abdel Khalek Abdel Razek

Bone-related disorders of the jaw (BRDJ) include a spectrum of non-neoplastic and neoplastic lesions of the maxillofacial region that have been recently classified into fibro-osseous lesions, giant cell lesions and osseous tumours. The histopathological features of BRDJ can be similar and overlie each other. Imaging is important in order to reach a specific diagnosis. However, the appearance of BRDJ on imaging is non-specific in some cases. Computed tomography (CT) and magnetic resonance imaging (MRI) are used for accurate localisation, characterisation of the tumour matrix, delineation of the lesion extension and establishment of the relation of BRDJ to the surrounding structures. Imaging is usually done to detect the relationship with the adjacent surrounding vital structures and to diagnose aggressive forms, malignant transformation and associated syndromes. The correlation of the demographic findings, the location and the clinical presentations with the imaging features are important for the diagnosis of BRDJ. The proposed clinico-radiological diagnostic algorithm with CT and MRI helps a specific diagnosis to be reached in some cases.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lee Curtin ◽  
Paula Whitmire ◽  
Haylye White ◽  
Kamila M. Bond ◽  
Maciej M. Mrugala ◽  
...  

AbstractLacunarity, a quantitative morphological measure of how shapes fill space, and fractal dimension, a morphological measure of the complexity of pixel arrangement, have shown relationships with outcome across a variety of cancers. However, the application of these metrics to glioblastoma (GBM), a very aggressive primary brain tumor, has not been fully explored. In this project, we computed lacunarity and fractal dimension values for GBM-induced abnormalities on clinically standard magnetic resonance imaging (MRI). In our patient cohort (n = 402), we connect these morphological metrics calculated on pretreatment MRI with the survival of patients with GBM. We calculated lacunarity and fractal dimension on necrotic regions (n = 390), all abnormalities present on T1Gd MRI (n = 402), and abnormalities present on T2/FLAIR MRI (n = 257). We also explored the relationship between these metrics and age at diagnosis, as well as abnormality volume. We found statistically significant relationships to outcome for all three imaging regions that we tested, with the shape of T2/FLAIR abnormalities that are typically associated with edema showing the strongest relationship with overall survival. This link between morphological and survival metrics could be driven by underlying biological phenomena, tumor location or microenvironmental factors that should be further explored.


2021 ◽  
Vol 2 ◽  
pp. 22-33
Author(s):  
Elena Titskaya ◽  
◽  
Konstantin Simonov ◽  
Evgeny Kabaev ◽  
Alexander Matsulev ◽  
...  

The results of computer visualization of the biomechanics of the shoulder joint are presented. Possibilities of using biomechanical robotic mechanotherapy, implemented using the CON-TREX complex, in the rehabilitation of patients after arthroscopic shoulder surgery. The possibilities of clarifying visualization using magnetic resonance imaging (MRI) using spectral decomposition methods (shearlet transform and contrasting with color coding) have been studied. The relationship between MRI data and CON-TREX protocols in planning and carrying out rehabilitation procedures has been shown. The relationship between MRI data and CON-TREX protocols in planning and carrying out rehabilitation procedures has been shown. A method is described that makes it possible to improve the quality and availability of MRI data when studying the biomechanics of the shoulder joint during rehabilitation.


2019 ◽  
Vol 05 (02) ◽  
pp. e62-e64
Author(s):  
Jonathan Ruben Caballero Martel ◽  
Sara Estévez Sarmiento

AbstractHoffa's fat pad can be affected by a variety of tumors. Schwannomas are benign and typically solitary neoplasms of the peripheral nerve sheath; they are made up of the neoplastic Schwann cells and are usually located eccentrically. Malignant schwannomas are extremely uncommon. Here we report a case of an intra-articular schwannoma of the knee. A 54-year-old man presented with a painful lump in the medial aspect of the knee. Magnetic resonance imaging revealed a well-circumscribed intra-articular mass, which was later diagnosed as an intra-articular schwannoma based on biopsy findings.


2020 ◽  
Vol 54 (1) ◽  
pp. 3-9
Author(s):  
Yaw B. Mensah ◽  
Kwadwo Mensah ◽  
Hafisatu Gbadamosi ◽  
Naa A. Mensah

Background: The use of Magnetic Resonance Imaging (MRI) is new in Ghana compared with some Western countries.A number of studies have observed increased MRI utilization due to increased sensitivity to diagnosis, and the paradigm shift to modalities that do not use radiation. Challenges with MRI use include high cost of the examination and inappropriate requests by referring clinicians. Objective: To determine the MRI utilisation trend in Korle Bu Teaching Hospital (KBTH), Ghana and its policy implications. Materials and Methods: A retrospective study undertaken in the Radiology Department, KBTH, from February to March, 2017. Eight hundred and forty request forms for MRI studies between January, 2013 and December 2016 were reviewed. Information on patient’s age and sex, number of MRI studies done, body parts and clinical conditions evaluated, appropriateness of clinical requests and existing policies on MRI in Ghana was gathered. Measures of central tendency and spread were obtained. Chi square, Pearson’s correlation and linear regression analysis were also used in the analysis. Results: The top three body parts requested were Spine (55 %), Brain (19%) and Joints (6 %); degenerative disease was the most common clinical condition evaluated.Significant association and correlation were obtained between of the number of body parts evaluated and examination year as well as the variety of clinical conditions requested and examination year. Conclusion: A progressive increase was noted in MRI utilisation both in number and diversity but no policy guiding MRI use in Ghana exists.


2000 ◽  
Vol 6 (5) ◽  
pp. 320-326 ◽  
Author(s):  
M Filippi

Gadolinium-enhanced magnetic resonance imaging (MRI) is very sensitive in the detection of active lesions of multiple sclerosis (MS) and has become a valuable tool to monitor the evolution of the disease either natural or modified by treatment. In the past few years, several studies, on the one hand, have assessed several ways to increase the sensitivity of enhanced MRI to disease activity and, on the other, have investigated in vivo the nature and evolution of enhancing lesions using different non-conventional MR techniques to better define the relationship between enhancement and tissue loss in MS. The present review is a summary of these studies whose results are discussed in the context of MS clinical trial planning and monitoring.


Neurosurgery ◽  
2018 ◽  
Vol 85 (6) ◽  
pp. 786-792 ◽  
Author(s):  
Thomas J Wilson ◽  
Kimberly K Amrami ◽  
B Matthew Howe ◽  
Robert J Spinner

ABSTRACT BACKGROUND Management of intraneural perineuriomas remains controversial, largely due to the lack of knowledge regarding the natural history of these lesions. OBJECTIVE To describe the typical radiological growth pattern of intraneural perineuriomas and to determine how the pattern of growth relates to clinical progression. METHODS We performed a retrospective review of the magnetic resonance imaging (MRI) studies and serial clinical examinations of a cohort of patients with biopsy-proven intraneural perineuriomas who had 2 MRI studies at least 2 yr apart. The outcome of interest was radiological growth in length or width of the intraneural perineurioma. Radiological growth was tested for association with clinical progression. RESULTS Twenty patients were included in the study. By width, the lesions were on average larger on repeat imaging (P = .009). By absolute length, the lesions were on average longer on repeat imaging (P = .02). By lesion:landmark ratio, there was no difference in length of the lesions between sequential images (P = .09), with 10 (50%) lesions being shorter and 7 (35%) showing no change. No lesions grew to involve a new nerve or division of a nerve on sequential imaging. None of the variables tested were associated with clinical progression. CONCLUSION We found that intraneural perineuriomas only rarely grow in length, do not grow to involve new nerves or nerve divisions, and growth does not correlate with clinical progression. These findings have significant ramifications for management of these tumors.


2016 ◽  
Vol 7 (3) ◽  
pp. 373-383 ◽  
Author(s):  
F. Draghi ◽  
G. Ferrozzi ◽  
L. Urciuoli ◽  
C. Bortolotto ◽  
S. Bianchi

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