Meeting online contacts in real life among adolescents: The predictive role of psychosocial wellbeing and internet-specific parenting

2012 ◽  
Vol 28 (2) ◽  
pp. 465-472 ◽  
Author(s):  
Annette Van den Heuvel ◽  
Regina J.J.M. van den Eijnden ◽  
Antonius J. van Rooij ◽  
Dike van de Mheen
2016 ◽  
Vol 137 ◽  
pp. 221-223 ◽  
Author(s):  
Luca Masotti ◽  
Valerio Verdiani ◽  
Marco Cei ◽  
Adriano Cioppi ◽  
Massimo Di Natale ◽  
...  

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Agurne Sampedro ◽  
Javier Peña ◽  
Pedro Sánchez ◽  
Naroa Ibarretxe-Bilbao ◽  
Nagore Iriarte-Yoller ◽  
...  

AbstractFunctional impairment remains one of the most challenging issues for treatment in schizophrenia. However, previous studies have mainly focused on the negative impact of symptoms excluding variables that could positively impact functional outcome, such as creativity, which is considered an adaptive capacity for real-life problem-solving. This study analyzed the predictive role of creativity on functional outcome in 96 patients with schizophrenia through a mediational model, including sociodemographic, clinical, neurocognitive, and social cognitive variables. Path analysis revealed that creativity significantly mediated the relationship between neurocognition and functional outcome, and that creativity mediated between negative symptoms and functional outcome. Additionally, neurocognition was directly associated with functional outcome and social functioning was associated with creativity. The involvement of creativity in functional outcome could have relevant implications for the development of new interventions. These findings open up a new field of research on additional personal resources as possible factors of functional outcome in schizophrenia and other diseases.


2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e12027-e12027
Author(s):  
Ornella Garrone ◽  
Massimo Di Maio ◽  
Anna Maria Vandone ◽  
Rodolfo Brizio ◽  
Paola Vanella ◽  
...  

2019 ◽  
Vol 156 (6) ◽  
pp. S-1124
Author(s):  
Clara Caenepeel ◽  
Sara Vieira-Silva ◽  
Jorge F. Vázquez-Castellanos ◽  
Bram Verstockt ◽  
Marc Ferrante ◽  
...  

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 565
Author(s):  
Angela Toss ◽  
Claudia Piombino ◽  
Elena Tenedini ◽  
Alessandra Bologna ◽  
Elisa Gasparini ◽  
...  

Previous research involving epithelial ovarian cancer patients showed that, compared to germline BRCA (gBRCA) mutations, somatic BRCA (sBRCA) mutations present a similar positive impact with regard to overall survival (OS) and platinum and PARP (poly (ADP-ribose) polymerase) inhibitor sensitivity. Nevertheless, molecular testing in these studies did not include copy number variation (CNV) analyses of BRCA genes. The aim of this study was to explore the prognostic and predictive role of sBRCA mutations as compared to gBRCA mutations in patients who were also tested for CNVs. Among the 158 patients included in the study, 17.09% of patients carried a pathogenic or likely pathogenic gBRCA variant and 15.19% of patients presented pathogenetic or likely pathogenic sBRCA variants and/or CNVs. Overall, 81.6% of the patients included in this study were diagnosed with a serous histotype, and 77.2% were in advanced stages. Among women diagnosed in advanced stages, gBRCA patients showed better progression-free survival and OS as compared to sBRCA and wild-type patients, whereas sBRCA patients did not show any advantage in outcome as compared to wild-type patients. In this study, the introduction of CNV analyses increased the detection rate of sBRCA mutations, and the resulting classification among gBRCA, sBRCA and wild-type patients was able to properly stratify the prognosis of OC patients. Particularly, sBRCA mutation patients failed to show any outcome advantage as compared to wild-type patients.


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