Ultrasound-assisted extraction of biologically active compounds and their successive concentration by using membrane processes

2019 ◽  
Vol 147 ◽  
pp. 378-389 ◽  
Author(s):  
Anna Trojanowska ◽  
Iren Tsibranska ◽  
Daniela Dzhonova ◽  
Michalina Wroblewska ◽  
Monika Haponska ◽  
...  
2008 ◽  
Vol 3 (9) ◽  
pp. 1934578X0800300 ◽  
Author(s):  
Antoaneta Trendafilova ◽  
Milka Todorova

The effect of ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE) and conventional extraction (CE) on the extraction of biologically active compounds from Achillea millefolium Proa has been investigated. The extracts were analyzed by spectrophotometric methods. The influence of the extraction time and the solvent on the yields of total extract (TEC), total phenolic compounds (TPhC), flavonoids (FC) and sesquiterpene lactones (SLC) has been studied. It was found that TEC and TPhC increased with increasing the solvent polarity in order CHCl3, MeOH and 80% MeOH. The extraction with MeOH gave maximum amount of flavonoids, while the SLC was found to be almost equal in all used solvents. UAE for 60 min and MAE for 60 s afforded higher or almost equal TEC, TPhC and FC than those obtained by CE for 24 h. The best extraction of sesquiterpene lactones was achieved with CHCl3 for 20 min of ultrasound treatment and 20 s of microwave irradiation.


2020 ◽  
Vol 12 (5) ◽  
pp. 1871 ◽  
Author(s):  
Katarzyna Godlewska ◽  
Anita Biesiada ◽  
Izabela Michalak ◽  
Paweł Pacyga

This research presents the possibility of using innovative botanical extracts as biostimulants of plant growth to improve plant nutritional value, growth, and development. It is important to increase agricultural production but this process should be carried out in a sustainable way, without causing risks for both the environment and consumers. For this reason, we have focused on the use of 14 natural raw materials and ultrasound assisted extraction for the production of biostimulants. Results proved that higher plants can be used to obtain valuable products for the application in modern horticulture and agriculture. For instance, extract based on Urtica dioica L. showed the highest biostimulatory properties: in the group sprayed with 0.1% extract cabbage seedlings were longer by 31%, while with 1.0% extract of Polygonum aviculare L. roots were longer by 72% than in the control group treated with water. Extracts based on Equisetum arvense L. (0.5%) and Urtica dioica L. (leaf) (0.1%) increased the fresh weight of sprouts by 113% and 112%, respectively. The highest root weight was observed in groups treated with Equisetum arvense L. (0.5%), Polygonum aviculare L. (0.5%), and Urtica dioica L. (leaf) (2.5%)—heavier by 207%, 206%, and 205%, respectively. Most of biostimulants increased the content of pigments involved in photosynthesis (e.g. 156% more chlorophyll for 0.1% Hypericum perforatum L. extract), decreased the content of polyphenols (e.g. 47% less for 2.5% Trifolium pretense extract), and showed a varied impact on antioxidant activity. There is an increasing interest in botanical extracts due to their high content of biologically active compounds and wide variety of application possibilities.


2014 ◽  
Vol 1073-1076 ◽  
pp. 122-126
Author(s):  
Qiao Yang

In this study, a novel microwave-assisted extraction (MAE) method has been developed for the extraction and determination of the major biologically active compounds, crocin and its seven trans-cis analogues in a traditional Chinese medicine (TCM), gardenia fruits (Gardenia jasminoides Ellis) with analysis by reversed phase HPLC. Sudan I [1-phenylazo-2-naphthol] was selected as the internal standard. The results of quantitative determination of seven crocin analogues in six commercial gardenia fruits samples show that MAE–HPLC is a simple, rapid, low cost and reliable method for the determination of biologically active compounds, crocin analogues in TCM, and also a potential and powerful tool for quality assessment of gardenia fruits (Gardenia jasminoides Ellis).


2009 ◽  
Vol 4 (7) ◽  
pp. 1934578X0900400 ◽  
Author(s):  
Jordanka Staneva ◽  
Milka Todorova ◽  
Neyko Neykov ◽  
Ljuba Evstatieva

This work deals with ultrasonically assisted extraction (UAE) of biologically active compounds from rhizomes of Rhodiola rosea, a popular medicinal plant. The influence of temperature, type of solvent and solid/solvent ratio on the yield of total extracts, total phenols and flavonoids was established. The best extraction of total phenols and flavonoids was achieved by using 50% aqueous EtOH and MeOH, respectively. Five times increase of solid/solvent ratio (from 1:20 to 1:100 (w/v)) leads to slow increase of the yield of total phenols and flavonoids. The extraction effectiveness of conventional maceration with 50% EtOH and UAE performed for 1 h at 25°C using the same solvent with respect of total phenols was comparable.


2019 ◽  
Vol 4 (2) ◽  

There is a worldwide demand for phenolic compounds (PC) because they exhibit several biological activities. This work aimed at extracting phenolic compounds from peanut meal. The methods of extraction were mainly: conventional solvent extraction (traditional methods) and ultrasound assisted extraction (recent methods) and comparing their results. Peanut meal (PM) was prepared by defatting with n-hexane, and then extracted by the two previous methods. First, the conventional solvents used were 80% methanol, ethanol, acetone, isopropanol, and distilled water. Then studied Different parameters such as meal: water ratio, also the effect of temperature and the pH on the extraction process. Second, ultrasonic assisted extractions (USAE), the parameters investigated were temperature, time and speed of sonication. Finally, all the extracts were analyzed by HPLC for their phenolic contents. Results indicated that the highest extracted PC achieved by solvents was in distilled water where 1:100, Meal: Water ratio which extracted 40 mg PC / g PM at 30& 35°C. Highest extracted PC was achieved by alkaline medium at pH 12 more than acidic and neutral medium. While (USAE) at speed 8 ultrasonication and temperature 30ᵒC, extracted 49.2mg PC /g PM. Sothe ultrasound assisted extraction exhibited great influence on the extraction of phenolic compounds from peanut meal. The ultrasonic peanut extract was examined for its antioxidant, antimicrobial and anticarcinogenic activities. The antioxidant activity of PM phenolic extract prepared by ultrasonic technique, was measured by, β-carotene, and DPPH methods, and reducing antioxidant power. Results revealed values: 84.57, 57.72 and 5960 respectively. The PM extract showed different levels of antimicrobial activity against the pathogenic bacteria used. As for the anticarcinogenic effect PM phenolic extract most effective on inhibiting colon carcinoma and lung carcinoma cell lines with IC50 = 20.7 and 20.8 µ/ml., respectively. This was followed by intestinal carcinoma and liver carcinoma cell lines with IC50= 39.6 and 40.2µ/ml.


2018 ◽  
Author(s):  
Honggui Lv ◽  
Li-Jun Xiao ◽  
Dongbing Zhao ◽  
Qi-Lin Zhou

Herein, we realized the first linear-selective hydroarylation of unactivated alkenes and styrenes with organoboronic acids by introducing directing groupon alkenes. Our method is highly efficient and scalable, and provides a modular route to assemble structurally diverse alkylarenes, especially for γ-aryl butyric acid derivatives, which have been widely utilized as chemical feedstocks to access multiple marketed drugs, and biologically active compounds.<br>


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