Interlobular Septal Thickening in a Young Man With Dyspnea

Background: Coronaviruses are non-segmented enveloped positive-sense single-strand RNA viruses, and COVID-19 is the seventh known coronavirus, infecting humans. Objective: As the COVID-19 continued to spread the world wildly, every radiologist or clinician needs to be familiar with its imaging findings. Methods: In this study, we reviewed available studies to provide a comprehensive statement on COVID-19 imaging findings. Results: Ground-glass opacities, linear opacities, interlobular septal thickening, consolidation, and Crazy-paving patterns are the most frequent findings in computed tomography (CT) of lungs in patients with COVID-19 pneumonia, which are mostly bilateral, multifocal, and peripheral. Staff needs to follow some rules to reduce infection transmission. Conclusion: COVID-19 pneumonia is a new global concern which has many unknown features. In this article, the radiologic characteristics of COVID-19 pneumonia are discussed. We also discussed appropriate protective measures that the radiology team should be aware of.

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Cross-sectional analysis of follow-up chest MRI and chest CT scans in patients previously affected by COVID-19

La radiologia medica ◽

10.1007/s11547-021-01390-4 ◽

2021 ◽

Author(s):

Martina Pecoraro ◽

Stefano Cipollari ◽

Livia Marchitelli ◽

Emanuele Messina ◽

Maurizio Del Monte ◽

...

Keyword(s):

Chest Ct ◽

Ct Scans ◽

Imaging Biomarker ◽

Cross Sectional ◽

Mri Scans ◽

Magnetic Resonance Imaging Mri ◽

Sectional Analysis ◽

Ct And Mri ◽

Interlobular Septal Thickening

Abstract Purpose The aim of the study was to prospectively evaluate the agreement between chest magnetic resonance imaging (MRI) and computed tomography (CT) and to assess the diagnostic performance of chest MRI relative to that of CT during the follow-up of patients recovered from coronavirus disease 2019. Materials and methods Fifty-two patients underwent both follow-up chest CT and MRI scans, evaluated for ground-glass opacities (GGOs), consolidation, interlobular septal thickening, fibrosis, pleural indentation, vessel enlargement, bronchiolar ectasia, and changes compared to prior CT scans. DWI/ADC was evaluated for signal abnormalities suspicious for inflammation. Agreement between CT and MRI was assessed with Cohen’s k and weighted k. Measures of diagnostic accuracy of MRI were calculated. Results The agreement between CT and MRI was almost perfect for consolidation (k = 1.00) and change from prior CT (k = 0.857); substantial for predominant pattern (k = 0.764) and interlobular septal thickening (k = 0.734); and poor for GGOs (k = 0.339), fibrosis (k = 0.224), pleural indentation (k = 0.231), and vessel enlargement (k = 0.339). Meanwhile, the sensitivity of MRI was high for GGOs (1.00), interlobular septal thickening (1.00), and consolidation (1.00) but poor for fibrotic changes (0.18), pleural indentation (0.23), and vessel enlargement (0.50) and the specificity was overall high. DWI was positive in 46.0% of cases. Conclusions The agreement between MRI and CT was overall good. MRI was very sensitive for GGOs, consolidation and interlobular septal thickening and overall specific for most findings. DWI could be a reputable imaging biomarker of inflammatory activity.

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Study on the Dynamic Changes in Chest CT Findings of COVID-19 Rehabilitated Patients

Journal of Cardiology Research ◽

10.36879/jcr.20.000132 ◽

2020 ◽

pp. 1-7

Keyword(s):

Disease Progression ◽

Onset Time ◽

Ground Glass Opacity ◽

Chest Ct ◽

Ground Glass ◽

Dynamic Changes ◽

Course Of Disease ◽

Pleural Thickening ◽

Ct Findings ◽

Interlobular Septal Thickening

Objective: To study the dynamic changes in CT findings in COVID-19 (coronavirus disease-19, COVID-19) rehabilitated patients. Methods: A total of 148 chest CT images of 37 patients with COVID-19 were collected. In the first 21 days of the course of disease, 7 stages were performed every 3 days, and the eighth stage was performed after 21 days. Results: In the first chest CT examination, 19 cases were ground glass opacity, and 18 cases were high-density shadows with consolidation. The lesion shape was flaky and patchy in 33 cases. The percentage of consolidation, air bronchogram, fiber cord, interlobular septal thickening, subpleural line and pleural thickening were the highest on days 4-6, 7-9, 7-9, 10-12, 19-21 and 19-21, respectively. The highest percentage of disease progression was 80.00% on days 4-6, and then the percentage of disease progression gradually decreased with the extension of the onset time. The percentage of patients with improvement gradually increased from days 4-6, reaching 83.33% on days 16-18 and 100.00% on day 21. The percentage of lesion range enlargement and density increase was the highest on days 4-6, both of which were 60.00%，Then the percentage of both decreased gradually. The percentage of patients with lesion range reduction and density absorption dilution increased gradually with the onset time. There was no obvious regularity in the number of lesions. Conclusion: Patients with COVID-19 have regular changes in their lung conditions.

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Clinical and Dynamic Computed Tomography Features of 24 Patients With Coronavirus Disease 2019

Canadian Association of Radiologists Journal ◽

10.1177/0846537120918834 ◽

2020 ◽

pp. 084653712091883 ◽

Cited By ~ 4

Author(s):

Bingkun Jie ◽

Xiaojin Liu ◽

Huaqian Suo ◽

Guoqing Qiao ◽

Qingshui Zheng ◽

...

Keyword(s):

Computed Tomography ◽

Clinical Characteristics ◽

Close Contact ◽

Dynamic Computed Tomography ◽

Chest Tightness ◽

Wuhan City ◽

Travel History ◽

Chest Computed Tomography ◽

Regional Center ◽

Interlobular Septal Thickening

Purpose: To explore the clinical and dynamic computed tomography features of coronavirus disease 2019. Methods: We enrolled 24 patients with coronavirus disease 2019 treated at a regional center in Dezhou, China, from January 22 to February 5, 2020, and analyzed data retrospectively. Results: Nineteen cases had close contact with people with coronavirus disease 2019, and five patients denied a travel history in Wuhan City or contact with patients having coronavirus disease 2019. Symptoms were fever, cough, chest tightness, dyspnea, fatigue, and muscle pain. Chest computed tomography showed multiple ground-glass opacities distributed along peribronchial bundles and subpleural areas, often accompanied by bronchiectasis, vascular thickening, and interlobular septal thickening after coronavirus disease 2019 progression. Conclusions: Coronavirus disease 2019 has certain clinical characteristics and typical computed tomography features.

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Imaging findings of pulmonary manifestations of chronic granulomatous disease in a large single center from Shanghai, China (1999–2018)

Scientific Reports ◽

10.1038/s41598-020-76408-4 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Qiong Yao ◽

Qin-hua Zhou ◽

Quan-li Shen ◽

Zhong-wei Qiao ◽

Xiao-chuan Wang ◽

...

Keyword(s):

Chronic Granulomatous Disease ◽

Interstitial Pneumonia ◽

Fungal Infections ◽

Imaging Features ◽

Granulomatous Disease ◽

Axillary Lymphadenopathy ◽

Multiple Organs ◽

Pulmonary Manifestations ◽

Pulmonary Abnormalities ◽

Interlobular Septal Thickening

Abstract Chronic granulomatous disease (CGD) is characterized by recurrent infections and granuloma formation in multiple organs, especially the lung. We aimed to investigate pulmonary manifestations by computed tomography (CT). In total, 100 patients with 117 episodes of pulmonary infection were included. Chest CT scans of every episode were analyzed. Random nodules were the most common findings (79.49%), followed by ground-grass opacities (74.36%), focal consolidations (62.39%), and masses (59.83%). Cavities (12.82%) and multiple small abscesses (17.09%) could be found in the consolidations and masses. CT revealed interstitial pneumonia with tree-in-bud opacities (17.09%), interlobular septal thickening (23.08%) and emphysema (35.04%), which were more severe in the bilateral upper lobes. Mediastinal and hilar lymphadenopathy (78.63%) and axillary lymphadenopathy (65.81%) were common. Fungal infection (n = 27) was the most common and presented with multiple nodules and masses. Approximately 1/4 of fungal infections had interstitial pneumonia. In Staphylococcus aureus (n = 6) and Klebsiella pneumoniae (n = 3) infections, large areas of consolidation were common. In tuberculosis infection, the pulmonary infections were more severe and complex. For Bacillus Calmette-Guérin disease, left-sided axillary lymphadenopathy was a characteristic manifestation. CT images of CGD demonstrated variable pulmonary abnormalities. The main infectious organisms have unique imaging features.

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Interlobular Septal Thickening

Specialty Imaging: Thoracic Neoplasms ◽

10.1016/b978-0-323-37706-5.50019-6 ◽

2016 ◽

pp. 48

Keyword(s):

Interlobular Septal Thickening

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COVID-19 pneumonia: The first two chest CTs in the Bamrasnaradura Infectious Disease Institute

The ASEAN Journal of Radiology ◽

10.46475/aseanjr.2020.10 ◽

2020 ◽

pp. 69-81

Author(s):

Panyaros Kongpanya ◽

Parichut Vongthawatchai ◽

Priyanut Atiburanakul ◽

Nayot Panitanum ◽

Patama Suttha

Keyword(s):

Infectious Disease ◽

Ground Glass Opacity ◽

Chest Ct ◽

Lung Involvement ◽

Chest Computed Tomography ◽

Ct Findings ◽

Infectious Disease Institute ◽

The World ◽

Bilateral Lung ◽

Interlobular Septal Thickening

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread rapidly around the world. We reported the first two cases of COVID-19 pneumonia who had the chest computed tomography (CT) performed at the Bamrasnaradura Infectious Disease Institute (BIDI). The chest CT findings in the two patients with COVID-19 pneumonia showed bilateral lung involvement, multifocal involvement, peripheral distribution, ground glass opacity (GGO), consolidation and GGO with interlobular septal thickening (“crazy-paving” pattern). The chest CT findings in these patients are nonspecific and overlapped with other diseases.

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CT findings of patients infected with SARS-CoV-2

10.21203/rs.3.rs-16147/v1 ◽

2020 ◽

Author(s):

Xiaoyang Wang ◽

Chenbin Liu ◽

Liang Hong ◽

Cuiyun Yuan ◽

Jiguang Ding ◽

...

Keyword(s):

Wall Thickening ◽

Bronchial Wall ◽

Pleural Thickening ◽

Ct Findings ◽

Lymph Node Enlargement ◽

Peripheral Area ◽

Reversed Halo Sign ◽

The Common ◽

Single Lesion ◽

Interlobular Septal Thickening

Abstract Objective: we aimed to describe the chest CT findings in sixty-seven patientsinfected by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Method and material: We retrospectively reviewed 67 patients hospitalized in Ruian People's Hospital. All the patients received the positive diagnosis of SARS-CoV-2 infection. The CT and clinical data were collected between January, 23 and February, 10, 2020. The CT images were analyzed by the radiologists.Conclusion: There are 54 patients with positive CT findings and 13 patients with negative CT findings. The common CT findings in hospitalized patients with SARS-CoV-2 infection were ground glass opacities (42/54), lesions located in the peripheral area (50/54), multiple lesions(46/54), and lesions located in the lower lobes (42/54). There were some less common CT findings: air bronchogram (n=18), pleural thickening or pleural effusion (14/54), consolidation (12/54), lesions in the upper lobes (12/54), interlobular septal thickening (11/54), reversed halo sign (9/54), single lesion (8/54), cavitaties (4/54), bronchial wall thickening (3/54), intrathoracic lymph node enlargement (2/54).

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Para-aortic lymphadenopathy associated with adult COVID-19 multisystem inflammatory syndrome

BMJ Case Reports ◽

10.1136/bcr-2021-246884 ◽

2021 ◽

Vol 14 (12) ◽

pp. e246884

Author(s):

Victor Carvalho ◽

Paula H Damasco ◽

Thiago S Mello ◽

Bruno Gonçalves

Keyword(s):

Complete Resolution ◽

High Flow ◽

Nasopharyngeal Swab ◽

Minimal Amount ◽

High Flow Nasal Cannula ◽

Reverse Transcription Pcr ◽

Aortic Lymph Node ◽

Inflammatory Syndrome ◽

Swab Specimen ◽

Interlobular Septal Thickening

A 21-year-old woman arrived at the emergency department with dyspnoea, arterial hypotension and abdominal pain after 5 days with a influenza-like syndrome. SARS-CoV-2 was detected by reverse transcription PCR in a nasopharyngeal swab specimen. CT of the chest and abdomen with contrast demonstrated a minimal amount of free intraperitoneal fluid, gallbladder with wall oedema, multiple para-aortic lymph node and interlobular septal thickening with ground glass opacities on the lungs. No pleural effusion or thromboembolism. Early broad-spectrum antibiotics, high-flow nasal cannula and norepinephrine were started. She was successfully treated with intravenous immunoglobulin and pulse corticosteroid therapy with methylprednisolone. The patient was discharged home with complete resolution of her symptoms and returned to her previous health status.

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A 12-Year-Old Girl With Dyspnea and Unilateral Interlobular Septal Thickening

CHEST Journal ◽

10.1016/j.chest.2019.03.022 ◽

2019 ◽

Vol 156 (3) ◽

pp. e57-e61

Author(s):

Yong Chen ◽

Yao Xiao ◽

Ying Zhang ◽

Guangfa Zhu ◽

Ruiyu Dou ◽

...

Keyword(s):

Interlobular Septal Thickening

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