Ultra-fast high-efficiency enantioseparations by means of a teicoplanin-based chiral stationary phase made on sub-2μm totally porous silica particles of narrow size distribution

2016 ◽  
Vol 1427 ◽  
pp. 55-68 ◽  
Author(s):  
Omar H. Ismail ◽  
Alessia Ciogli ◽  
Claudio Villani ◽  
Michela De Martino ◽  
Marco Pierini ◽  
...  
Keyword(s):  
Stationary Phase ◽  
Size Distribution ◽  
Chiral Stationary Phase ◽  
High Efficiency ◽  
Porous Silica ◽  
Silica Particles ◽  
Narrow Size Distribution

Preparation of Narrow Size Distribution Silica Particles Using Microemulsions

Langmuir ◽  
1997 ◽  
Vol 13 (24) ◽  
pp. 6400-6406 ◽  
Author(s):  
J. Esquena ◽  
Th. F. Tadros ◽  
K. Kostarelos ◽  
C. Solans
Keyword(s):  
Size Distribution ◽  
Silica Particles ◽  
Narrow Size Distribution

An Experimental Study on Synthesis and Characterization of Silica Nanoparticles Prepared by Sol-Gel Method

2007 ◽  
Vol 553 ◽  
pp. 245-251
Author(s):  
Ali Shokuhfar ◽  
Tolou Shokuhfar ◽  
M. Ghazinejad ◽  
R. Babazade ◽  
S. Tabatabae
Keyword(s):  
Electron Microscopy ◽  
Silica Nanoparticles ◽  
Size Distribution ◽  
Sol Gel ◽  
Sio2 Nanoparticles ◽  
Industrial Applications ◽  
Silica Particles ◽  
Narrow Size Distribution ◽  
Molar Ratios ◽  
Transmission Electron

Monodispersed nanometer-sized particles proved to be very important and advantageous in many industrial applications. One of the notable groups of these particles is silica (SiO2) nanoparticles which are widely utilized in developing numerous products such as electrical and thermal insulators, humidity sensors, varnish, etc. Since the quality of some of these products depends highly on the purity and size distribution of the silica particles, it is necessary to produce silica nanoparticles of narrow size distribution and very high purity. In this research silica nanoparticles, with a relatively narrow size distribution, have been synthesized via the hydrolysis reaction of tetraethoxisilane (TEOS) in the solution of deionized water and ethanol (C2H5OH), and in the presence of ammonia (NH3) as a catalyst. The nature, morphology and the size of the silica particles has been studied using Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and X-ray diffraction. Results indicate that the morphology, structure and the diameter of silica particles depend strongly on the molar ratios of the reactants.

scholarly journals Engineering Cyclodextrin Clicked Chiral Stationary Phase for High-Efficiency Enantiomer Separation

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Jian Tang ◽  
Shapopeng Zhang ◽  
Yuzhou Lin ◽  
Jie Zhou ◽  
Limin Pang ◽  
...  
Keyword(s):  
Stationary Phase ◽  
Chiral Stationary Phase ◽  
Enantiomer Separation ◽  
High Efficiency

Enantiomeric Separation of 1-Phenyl-1-Propanol Using Calix[4]Arene-Capped β-Cyclodextrin-Bonded Silica Particles as Chiral Stationary Phase in Capillary Electrochromatography

2013 ◽  
Vol 749 ◽  
pp. 304-308 ◽  
Author(s):  
Jia Zhao ◽  
Jun Li ◽  
E.L. Yong ◽  
Yin Han Gong
Keyword(s):  
Stationary Phase ◽  
Capillary Electrochromatography ◽  
Chiral Stationary Phase ◽  
Enantiomeric Separation ◽  
Silica Particles ◽  
Hydroxyl Groups ◽  
New Type ◽  
Phenolic Hydroxyl Groups ◽  
First Time ◽  
Calix Arene

A new type of calix [ arene-capped (3-(2-O-β-cyclodextrin)-2-hydroxypropoxy) propylsilyl-appended silica particles (C4CD-HPS) has been successfully used as chiral stationary phase (CSP) in capillary electrochromatography (CEC) for separation of enantiomers of 1-phenyl-1-propanol for the first time. C4CD-HPS contains a chiral selector with two recognition sites: calix [arene and β-cyclodextrin. Due to the cooperative functioning of the calix [arene and β-cyclodextrin, C4CD-HPS has exhibited excellent enantioselectivity for the enantiomers of 1-phenyl-1-propanol. After the multiple phenolic hydroxyl groups in the calix [arene moieties are ionized in the running buffer, the bonded stationary phase C4CD-HPS becomes negatively-charged to provide high electroosmotic flow (EOF) in CEC. Fast and high-resolution separation for enantiomers of 1-phenyl-1-propanol has been easily achieved on C4CD-HPS. This new type of chiral stationary phase has exhibited great potential for fast enantiomeric separations in CEC.

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