EXAGGERATED CARDIOMETABOLIC RISK FACTORS AND CARDIOVASCULAR DISEASE IN CANADIAN PRIMARY CARE PATIENTS WITH DIABETES AND ABDOMINAL OBESITY

2014 ◽  
Vol 30 (10) ◽  
pp. S304
Author(s):  
D.C. Lau ◽  
L.A. Leiter ◽  
J. Genest ◽  
S.B. Harris ◽  
P. Selby ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Primary Care ◽  
Abdominal Obesity ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Patients With Diabetes ◽  
Primary Care Patients

A Cross-Sectional Survey of Cardiometabolic Risk Factors in Canadian Primary Care Patients with Abdominal Obesity

2014 ◽  
Vol 38 (5) ◽  
pp. S45
Author(s):  
David C.W. Lau ◽  
Lawrence A. Leiter ◽  
Jacques J.G. Genest ◽  
Stewart B. Harris ◽  
Peter Selby ◽  
...  
Keyword(s):  
Risk Factors ◽  
Primary Care ◽  
Abdominal Obesity ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Primary Care Patients

Cardiometabolic Risk Factors in Canadian Primary Care Patients with Abdominal Obesity and Diabetes

2014 ◽  
Vol 38 (5) ◽  
pp. S45
Author(s):  
David C.W. Lau ◽  
Lawrence A. Leiter ◽  
Jacques J.G. Genest ◽  
Stewart B. Harris ◽  
Peter Selby ◽  
...  
Keyword(s):  
Risk Factors ◽  
Primary Care ◽  
Abdominal Obesity ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Obesity And Diabetes ◽  
Primary Care Patients

Abstract P148: Neck Circumference as an Independent Contributor to Cardio Metabolic Risk Factors - ELSA BRASIL

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Cristina P Baena ◽  
Paulo A Lotufo ◽  
Maria J Fonseca ◽  
Isabela J Benseñor
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Primary Care ◽  
Cardiometabolic Risk ◽  
Neck Circumference ◽  
Cardiometabolic Risk Factors ◽  
Metabolic Risk ◽  
Men And Women ◽  
Low Hdl

Background: Neck circumference is a proxy for upper body fat and it is a simple anthropometric measure. Therefore it could be a useful tool to identify individuals with cardiometabolic risk factors in the context of primary care. Hypothesis: Neck circumference is independently associated to cardiometabolic risk factors in an apparently healthy population. Methods: This is a cross-sectional analysis of baseline data of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), a cohort of 15105 civil servants aged 35-74 years. We excluded from this analysis those who fulfilled American Diabetes Association criteria for diabetes diagnosis, were taking antihypertensive and/or lipid-lowering drugs. A sex-specific analysis was conducted. Partial correlation (age-adjusted) was used. Risk factors were set as low HDL<50mg/dL for women and <40mg/dL for men, hypertriglyceridemia ≥ 150 mg/dl , hypertension as systolic blood pressure ≥130 mg/dl or diastolic blood pressure ≥85 mm Hg and insulin resistance(HOMA-IR ≥ 75th percentile). Logistic regression models were built to analyze the association between individual and clustered risk factors as dependent variables and 1-SD increase in neck circumference as independent variable. Multiple adjustments were subsequently performed for age, smoking, alcohol, body-mass index, waist and physical activity. Receiver Operating Curves were employed to find the best NC cut-off points for clustered risk factors. Results: We analyzed 3810 men (mean age= 49.0 ±8.3 yrs) and 4916 women (49.2 ±8.0 yrs). Mean NC was 38.9 (±2.6)cm for men and 33.4(±2.6)cm for women. NC positively correlated with systolic and diastolic blood pressure (r=0.21 and r=0.27), HOMA - IR (r=0.44), triglycerides (r=0.31) and negatively correlated with HDL (r= -0.21) in men (p<0.001 for all) with similar results in women. Fully adjusted Odds Ratio (OR) (95% CI) of risk factor per SD increase in neck circumference in men and women were 1.29(1.14;1.46) and 1.42(1.28;1.57) for insulin resistance; 1.24(1.11;1.39) and 1.25(1.11;1.40) for hypertension; 1.33(1.19;1.49) and 1.42(1.29;1.63) for hypertriglyceridemia; 1.07(0.92;1.23) and 1.32 (1.19;1.43) for low HDL. Fully adjusted OR (95% CI) of 2 clustered risk factor per SD increase in neck circumference in men and women were 1.29(1.14;1.48) and 1.37(1.21;1.54 ). Fully adjusted OR (95% CI) of 3 or more clustered risk factors per SD increase in neck circumference in men and women were 1.33 (1.02;1.74) and 1.62 (1.33;1.92). Values of neck circumference of >40 cm for men and >34.1 cm for women were the best cut-off points for 3 or more clustered risk factors. Conclusion: Neck circumference is significantly and independently associated to cardiometabolic risk factors in a well-defined non-treated population. It should be considered as a marker of cardio metabolic risk factors in primary care settings.

scholarly journals Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study

Diabetes Care ◽  
2019 ◽  
Vol 42 (4) ◽  
pp. 657-664 ◽  
Author(s):  
Barbara H. Braffett ◽  
Samuel Dagogo-Jack ◽  
Ionut Bebu ◽  
William I. Sivitz ◽  
Mary Larkin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Type 1 Diabetes ◽  
Cardiometabolic Risk ◽  
Insulin Dose ◽  
Cardiometabolic Risk Factors
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