Long-term effects of clinical interventions on nutritional status in patients with chronic pancreatitis - a systematic review

Author(s):  
M.E. Phillips ◽  
M.D. Robertson ◽  
K.H. Hart ◽  
R. Kumar ◽  
T.D. Pencavel
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sandra Lopez-Leon ◽  
Talia Wegman-Ostrosky ◽  
Carol Perelman ◽  
Rosalinda Sepulveda ◽  
Paulina A. Rebolledo ◽  
...  

AbstractCOVID-19 can involve persistence, sequelae, and other medical complications that last weeks to months after initial recovery. This systematic review and meta-analysis aims to identify studies assessing the long-term effects of COVID-19. LitCOVID and Embase were searched to identify articles with original data published before the 1st of January 2021, with a minimum of 100 patients. For effects reported in two or more studies, meta-analyses using a random-effects model were performed using the MetaXL software to estimate the pooled prevalence with 95% CI. PRISMA guidelines were followed. A total of 18,251 publications were identified, of which 15 met the inclusion criteria. The prevalence of 55 long-term effects was estimated, 21 meta-analyses were performed, and 47,910 patients were included (age 17–87 years). The included studies defined long-COVID as ranging from 14 to 110 days post-viral infection. It was estimated that 80% of the infected patients with SARS-CoV-2 developed one or more long-term symptoms. The five most common symptoms were fatigue (58%), headache (44%), attention disorder (27%), hair loss (25%), and dyspnea (24%). Multi-disciplinary teams are crucial to developing preventive measures, rehabilitation techniques, and clinical management strategies with whole-patient perspectives designed to address long COVID-19 care.


2021 ◽  
pp. 003232172110072
Author(s):  
Ramon van der Does ◽  
Vincent Jacquet

Deliberative minipublics are popular tools to address the current crisis in democracy. However, it remains ambiguous to what degree these small-scale forums matter for mass democracy. In this study, we ask the question to what extent minipublics have “spillover effects” on lay citizens—that is, long-term effects on participating citizens and effects on non-participating citizens. We answer this question by means of a systematic review of the empirical research on minipublics’ spillover effects published before 2019. We identify 60 eligible studies published between 1999 and 2018 and provide a synthesis of the empirical results. We show that the evidence for most spillover effects remains tentative because the relevant body of empirical evidence is still small. Based on the review, we discuss the implications for democratic theory and outline several trajectories for future research.


2021 ◽  
Vol 118 ◽  
pp. 110289
Author(s):  
Eman Merza ◽  
Stephen Pearson ◽  
Glen Lichtwark ◽  
Meg Ollason ◽  
Peter Malliaras

2007 ◽  
Vol 146 (7) ◽  
pp. 502 ◽  
Author(s):  
Noel T. Brewer ◽  
Talya Salz ◽  
Sarah E. Lillie

2016 ◽  
Vol 24 (1) ◽  
pp. 3-17 ◽  
Author(s):  
Johan Anton Jochum Keestra ◽  
Obada Barry ◽  
Lianne de Jong ◽  
Gerhard Wahl

2017 ◽  
Vol 17 (1) ◽  
pp. 7-15 ◽  
Author(s):  
Flavia Bittencourt Brasil ◽  
Luiz Henrique Amarante ◽  
Marcos Roberto de Oliveira

Abstract Objectives: describing the effects of maternal supplementation with folic acid (FA) exclusively during gestation on offspring's liver at later stages in life. Supplementation with FA during gestation has been recommended by the medical society worldwide. The liver has a central role on the substances of metabolism and homeostasis and some studies have shown that a high intake of FA at other periods in life may cause hepatic damage. Methods: a systematic review through which the following databases were consulted: Medline, through platforms of Pubmed, Lilacs and Scielo. The research was performed by keywords such as: "Folic acid", "Gestation", "Rat", "Offspring" and "Liver". Articles which evaluate the effect of FA consumption during both gestation and lactation were excluded. Results: FA consumption avoids disorders on expression of peroxisome proliferator-activated receptor alpha (PPARα) and glucocorticoid receptor (GccR), its lack did not change enzyme activity of the male offspring's liver in adulthood. Supplementation with FA during gestation did not change iron hepatic levels or lipid composition, but had an antioxidant effect on it. Conclusions: supplementation with FA at recommended doses did not cause toxic effects and is very likely to avoid deleterious effects in the liver of the offspring regarding the epigenetic level.


2020 ◽  
Vol 50 (6) ◽  
pp. 474-490 ◽  
Author(s):  
David A. Jett ◽  
Christopher A. Sibrizzi ◽  
Robyn B. Blain ◽  
Pamela A. Hartman ◽  
Pamela J. Lein ◽  
...  

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