Preventive and protective properties of rosemary (Rosmarinus officinalis L.) in obesity and diabetes mellitus of metabolic disorders: a brief review

2015 ◽  
Vol 2 ◽  
pp. 58-70 ◽  
Author(s):  
Rashin Sedighi ◽  
Yantao Zhao ◽  
Aaron Yerke ◽  
Shengmin Sang
2019 ◽  
Vol 22 (3) ◽  
pp. 253-262
Author(s):  
Elena V. Pokrovskaya ◽  
Minara S. Shamkhalova ◽  
Marina V. Shestakova

Obesity is a worldwide problem of the last century, the prevalence of which has reached pandemic proportions in developed countries. Over the past few years, a considerable amount of data has been gathered, reporting a direct link between changes in gut microbiota and the development of obesity, as well as related diseases, primarily, diabetes mellitus type 2. The elaboration of optimal methods of prevention and treatment regimens of these diseases needs to structure the existing knowledge about the mechanisms of development of metabolic disorders, the role of intestinal microbiota in the latter and possible therapeutic targets. This review examines the role of microorganisms in the human body, with the main focus on the developmental origins of metabolic disorders using animal models and accumulated experience of research on their effects on the human body, and also discusses possible treatment options, including bariatric surgery, fecal microbiota transplantation, the use of pre- and probiotics and certain particular groups of glucose-lowering drugs.


2021 ◽  
Vol 12 ◽  
Author(s):  
Eduardo Rivera-Mancilla ◽  
Linda Al-Hassany ◽  
Carlos M. Villalón ◽  
Antoinette MaassenVanDenBrink

Migraine is a disabling neurovascular disorder, characterized by moderate to severe unilateral headaches, nausea, photophobia, and/or phonophobia, with a higher prevalence in women than in men, which can drastically affect the quality of life of migraine patients. In addition, this chronic disorder is related with metabolic comorbidities associated with the patient's lifestyle, including obesity and diabetes mellitus (DM). Beyond the personal and socioeconomic impact caused by migraine, obesity and DM, it has been suggested that these metabolic disorders seem to be related to migraine since: (i) they are a risk factor for developing cardiovascular disorders or chronic diseases; (ii) they can be influenced by genetic and environmental risk factors; and (iii) while clinical and epidemiological studies suggest that obesity is a risk factor for migraine, DM (i.e., type 1 and type 2 DM) have been reported to be either a protective or a risk factor in migraine. On this basis, and given the high worldwide prevalence of migraine, obesity, and DM, this article provides a narrative review of the current literature related to the association between the etiology and pathophysiology of migraine and these metabolic disorders, considering lifestyle aspects, as well as the possible involvement of neurotransmitters, neuropeptides, and/or sex hormones. While a link between migraine and metabolic disorders has been suggested, many studies are contradictory and the mechanisms involved in this association are not yet sufficiently established. Therefore, further research should be focused on understanding the possible mechanisms involved.


2010 ◽  
Vol 54 (2) ◽  
pp. 150-157 ◽  
Author(s):  
Francisco J. A. de Paula ◽  
Clifford J. Rosen

Knowledge about the influence of bone on intermediary metabolism corresponds to a developing area that has gained prominence. The old concept of bone and adipose tissues as inert metabolic tissues, with minor contributions to metabolic adaptations has been reconsidered in light of findings that bone is involved in the development of insulin sensitivity. Similarly adipose tissue exerts important influences on bone mass development and maintenance. Moreover, the use of drugs in the treatment of metabolic disorders such as diabetes mellitus can impact bone metabolism. These networks linking osteoporosis to obesity and diabetes mellitus have reinvigorated investigations in the pathophysiology of osteoporosis. The present review examines this aspect and calls attention to health care providers and potential treatments of skeletal disorder.


2019 ◽  
Vol 2 (2) ◽  
pp. 16
Author(s):  
Eloisa Lorenzetti ◽  
Dablieny Hellen Garcia Souza ◽  
Juliano Tartaro ◽  
José Renato Stangarlin ◽  
Gilberto Costa Braga

A banana apresenta elevada suscetibilidade a doenças como as podridões que diminuem o tempo de prateleira do fruto. Uma das formas de controlar as doenças seria a utilização de métodos alternativos como os extratos de plantas medicinais. Assim, o objetivo deste estudo foi verificar a ação de formulados de alecrim (Rosmarinus officinalis L.) pó e líquido no controle de antracnose causada pelo fungo Colletotrichum musae (Berk & Curt.) Von Arx. e na maturação de banana ‘Nanicão’ em pós-colheita. Foram utilizadas as concentrações 0%; 0,25%; 0,5%; 1%; 1,5% e 2% do pó solúvel de extrato de alecrim diluído em água destilada, e as concentrações 0%; 0,5%; 1%; 2%; 4% e 6% do formulado aquoso contendo 21% de resíduo seco de alecrim diluído em água destilada. Foi realizada a mensuração da área de cada fruto e avaliada a severidade e a maturação a partir de porcentagem de área dos frutos, sendo os resultados utilizados para calcular a área abaixo da curva de progresso da doença (AACPD) e a porcentagem de maturação dos frutos. Realizou-se analise de regressão a partir dos dados obtidos e pode-se verificar que para o formulado de alecrim em pó a AACPD reduziu mais de 29% e para a maturação a redução foi de 21,72%. Para o formulado líquido a redução foi de 14,31% para AACPD e cerca de 10% para maturação. Assim, concluiu-se que houve eficiência por parte dos formulados de alecrim no controle da antracnose e no aumento da vida de prateleira da banana ‘Nanicão’.


2016 ◽  
Vol 72 (9) ◽  
Author(s):  
Dr. Ayman Salah El-Seedy ◽  
Hany George Shalaby ◽  
Mohamed Ahmed El-Sehrigy ◽  
Madiha Mohiy El-Dein Ghoneim

2020 ◽  
Vol 16 ◽  
Author(s):  
Mahnaz Mardani ◽  
Sadegh Rezapour

: Pregnancy-related complications can have long-term effects on mother and fetus/child. Microbiome within the human gut is an important factor to maintain optimum health during pregnancy and could possibly reduce the incidence of these complications. Probiotics are active living microorganisms that can provide the host with health benefits such as; immune and hormonal regulatory and metabolic benefits when administered in adequate and optimum dose. Probiotic supplementations also regulate abnormal and unbalanced microflora population that can control the pathogenesis of several diseases like obesity and diabetes. Probiotics also play a protective role in complications like preeclampsia, gestational diabetes mellitus and maternal weight gain and enhance successful outcomes of reproduction. This mini review will thereby summarize the maternal and fetal effects of probiotics during pregnancy.


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