Effect of surface charge and agglomerate degree of magnetic iron oxide nanoparticles on KB cellular uptake in vitro

2009 ◽  
Vol 73 (2) ◽  
pp. 294-301 ◽  
Author(s):  
Yuqing Ge ◽  
Yu Zhang ◽  
Jingguang Xia ◽  
Ming Ma ◽  
Shiying He ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Surface Charge ◽  
Iron Oxide Nanoparticles ◽  
Cellular Uptake ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide ◽  
Effect Of Surface

scholarly journals Transferrin-Decorated Niosomes with Integrated InP/ZnS Quantum Dots and Magnetic Iron Oxide Nanoparticles: Dual Targeting and Imaging of Glioma

2021 ◽  
Vol 22 (9) ◽  
pp. 4556
Author(s):  
Didem Ag Seleci ◽  
Viktor Maurer ◽  
Firat Baris Barlas ◽  
Julian Cedric Porsiel ◽  
Bilal Temel ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Glioma Cells ◽  
Oxide Nanoparticles ◽  
Enhancement Effect ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Nanoscale Systems ◽  
Magnetic Iron Oxide

The development of multifunctional nanoscale systems that can mediate efficient tumor targeting, together with high cellular internalization, is crucial for the diagnosis of glioma. The combination of imaging agents into one platform provides dual imaging and allows further surface modification with targeting ligands for specific glioma detection. Herein, transferrin (Tf)-decorated niosomes with integrated magnetic iron oxide nanoparticles (MIONs) and quantum dots (QDs) were formulated (PEGNIO/QDs/MIONs/Tf) for efficient imaging of glioma, supported by magnetic and active targeting. Transmission electron microscopy confirmed the complete co-encapsulation of MIONs and QDs in the niosomes. Flow cytometry analysis demonstrated enhanced cellular uptake of the niosomal formulation by glioma cells. In vitro imaging studies showed that PEGNIO/QDs/MIONs/Tf produces an obvious negative-contrast enhancement effect on glioma cells by magnetic resonance imaging (MRI) and also improved fluorescence intensity under fluorescence microscopy. This novel platform represents the first niosome-based system which combines magnetic nanoparticles and QDs, and has application potential in dual-targeted imaging of glioma.

scholarly journals Comparative In Vitro Study on Magnetic Iron Oxide Nanoparticles for MRI Tracking of Adipose Tissue-Derived Progenitor Cells

PLoS ONE ◽  
2014 ◽  
Vol 9 (9) ◽  
pp. e108055 ◽  
Author(s):  
Annika Kasten ◽  
Cordula Grüttner ◽  
Jens-Peter Kühn ◽  
Rainer Bader ◽  
Juliane Pasold ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Iron Oxide ◽  
Progenitor Cells ◽  
Iron Oxide Nanoparticles ◽  
In Vitro Study ◽  
Vitro Study ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide
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