Laboratory evaluation of long-term sealing behaviors of two water-swelling materials for shield tunnel gasket

2020 ◽  
Vol 249 ◽  
pp. 118711 ◽  
Author(s):  
Ji-Shuang Tan ◽  
Shui-Long Shen ◽  
Annan Zhou ◽  
Ze-Nian Wang ◽  
Hai-Min Lyu
Data in Brief ◽  
2020 ◽  
Vol 30 ◽  
pp. 105609
Author(s):  
J.S. Tan ◽  
S.L. Shen ◽  
A. Zhou ◽  
Z.N. Wang ◽  
H.M. Lyu

1997 ◽  
Vol 36 (10) ◽  
pp. 1-8 ◽  
Author(s):  
James D. Bryers ◽  
Robert R. Sharp

Exposure of plasmid recombinant microorganisms to an open environment, either inadvertently or intentionally, requires research into those fundamental processes that govern plasmid retention, transfer and expression. In the open environment, a majority of the microbial activity occurs associated with an interface, within thin biological layers consisting of cells and their insoluble extracellular polymer, layers known as biofilms. Current toxic wastewater or wastegas treatment reactors exploit bacterial biofilm systems for certain system operating advantages. Using recombinant bacteria within a biofilm reactor to degrade xenobiotic wastes requires finding a suitable host to harbor and express the desired plasmid phenotype. Suitable host characteristics include: the ability to produce copious amounts of biofilm, resistance to waste-related injury and toxicity, and the ability to retain and express the desired plasmid during long term operation. This paper reports on a laboratory evaluation of factors governing plasmid retention and the expression of trichloroethene (TCE) degradative capacity in both suspended and biofilm cultures.


1988 ◽  
Vol 33 (2) ◽  
pp. 103-107 ◽  
Author(s):  
Jonathan A.E. Fleming ◽  
Jean Bourgouin ◽  
Peter Hamilton

Six patients between the ages of 25 and 59, with chronic, primary insomnia received the new, non-benzodiazepine, hypnotic zopiclone continuously for 17 weeks after a drug free interval of 12 nights. To qualify for the study, sleep efficiency, determined by a sleep study on two, consecutive, placebo-controlled nights, had to be less than 75%. Patients evaluated their sleep by questionnaire and had sleep studies completed throughout active treatment. Zopiclone (7.5 mg) increased sleep efficiency by decreasing sleep latency, wakefulness after sleep onset and increasing total sleep time. Sleep architecture was minimally affected by zopiclone treatment; no significant changes in delta or REM sleep were observed. The commonest side effect was a bitter or metallic taste. No significant changes in biological functioning were noted throughout the study period. These findings indicate that zopiclone is a safe and effective hypnotic medication which maintains its effectiveness with protracted use.


1993 ◽  
Vol 4 (4) ◽  
pp. 997-1003
Author(s):  
J L Porile ◽  
M Richter

Preservation of vascular access is critical in the long-term successful management of hemodialysis patients. Dialysis access abnormalities are the most common cause of hospitalization in this patient group, and access problems can increase the morbidity and cost involved in the care of these patients. Native fistulas are preferable to synthetic grafts because of longer survival and a lower complication rate. Venous outflow stenosis is the most common site of obstruction in a failing graft. The pathophysiology of access failure is poorly understood, but it seems to be related to intimal hyperplasia in the native vessel downstream from the anastomosis. The stimulation of local growth factors by needle puncture may also play a role. An assessment of access adequacy includes careful physical examination, laboratory evaluation, and ultimately, angiography. Measurements of recirculation and venous pressure are commonly used to screen for access dysfunction, and their appropriate use will lower the incidence of graft loss in dialysis units. Treatment is usually either angioplasty or surgery, with some centers having success with thrombolytic therapy. New techniques such as atherectomy and stent placement may prove to be beneficial, but this requires further study.


Author(s):  
Biswajit K. Bairgi ◽  
A.S.M. Asifur Rahman ◽  
Rafiqul A. Tarefder ◽  
Matias M. Mendez Larrain

Warm-mix asphalt (WMA) technologies allow binder softening for compaction benefits. Lower production temperature also causes reduced short-term aging in WMA. Considering the long-term implication of the reduced aging and binder softening, WMA is being questioned about its rutting characteristics. As such, this study evaluates different WMA technologies for rutting characteristics in comparison to traditional hot-mix asphalt (HMA) through laboratory and field investigation. The study utilized the long-term pavement performance (LTPP) project in the state of New Mexico called Specific Pavement Study-10 (SPS-10), which was designed to evaluate the WMA performances. The LTPP SPS-10 section includes: (i) control HMA, (ii) foaming, (iii) Evotherm, (iv) Cecabase 1, and (v) Cecabase 2 mixtures. Cecabase 2 mixture consists of a polymer-modified binder (PG 70-28+), whereas other mixtures consist of PG 70-28 binder. The aggregate type, properties, and gradations are the same in all the sections. Laboratory evaluation of rutting was conducted through the Hamburg wheel tracking test. Long-term field rutting was evaluated through Mandli’s pavement profile scanner, a laser-based distress evaluation technology. The study found that WMA with foaming, Evotherm, or Cecabase shows slightly higher rutting compared with the control HMA; however, all the sections satisfied laboratory and field rutting criteria. The use of a polymer-modified binder in WMA significantly improves the rutting characteristics.


Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2331
Author(s):  
Enza Speranza ◽  
Lidia Santarpia ◽  
Maurizio Marra ◽  
Emilia De Filippo ◽  
Olivia Di Vincenzo ◽  
...  

Background: This study aimed to evaluate several socio-demographic and long-term clinical outcomes in a cohort of women living with a restrictive eating disorder. Methods: Patients were asked to fill in a general data collection form aiming to investigate their current conditions and to attend the outpatient unit for a 10-year follow-up clinical and laboratory evaluation. Results: Forty-four patients completed the follow-up general data collection form and 20 agreed to attend the outpatient unit for the 10 year-follow-up evaluation. In total, 52% of patients were single, 55% had achieved a university degree, and 55% had steady employment. After 10 years, there was a clear improvement in biochemical markers, but cholesterol levels were still slightly high. The prevalence of osteopenia in the whole sample was 70% when measured on the lumbar column and 20% on the total body, while osteoporosis was found in 10% of patients and only on the lumbar column. Conclusion: According to the collected data, women with a history of restrictive eating disorders appear to re-adapt well to social life by obtaining the level of their unaffected peers in terms of education and employment.


2017 ◽  
Vol 148 ◽  
pp. 30-37 ◽  
Author(s):  
Feng Li ◽  
Siqi Zhou ◽  
Wenyuan Cai ◽  
Yuchuan Du ◽  
Li Li

2012 ◽  
Vol 3S;15 (3S;7) ◽  
pp. ES145-ES156
Author(s):  
Jennifer A. Elliott

Opioid therapy is one of the most effective forms of analgesia currently in use. In the past few decades, the use of opioids as a long-term treatment for chronic pain has increased dramatically. Accompanying this upsurge in the use of long-term opioid therapy has been an increase in the occurrence of opioid associated endocrinopathy, most commonly manifested as an androgen deficiency and therefore referred to as opioid associated androgen deficiency (OPIAD). This syndrome is characterized by the presence of inappropriately low levels of gonadotropins (follicle stimulating hormone and luteinizing hormone) leading to inadequate production of sex hormones, particularly testosterone. Symptoms that may manifest in patients with OPIAD include reduced libido, erectile dysfunction, fatigue, hot flashes, and depression. Physical findings may include reduced facial and body hair, anemia, decreased muscle mass, weight gain, and osteopenia or osteoporosis. Additionally, both men and women with OPIAD may suffer from infertility. While the literature regarding OPIAD remains limited, it is apparent that OPIAD is becoming increasingly prevalent among chronic opioid consumers but often goes unrecognized. OPIAD can have a significant negative impact on the the quality of life of opioid users, and clinicians should anticipate the potential for its occurrence whenever long-term opioid prescribing is undertaken. Once diagnosed, treatment for OPIAD may be offered utilizing a number of androgen replacement therapy options including a variety of testosterone preparations and, for female patients with OPIAD, dehydroepiandrosterone (DHEA) supplementation. Follow-up evaluation of patients receiving androgen replacement therapy should include a review of any unresolved symptoms of hypogonadism, laboratory evaluation, and surveillance for potential adverse effects of androgen replacement therapy including prostate disease in males. Key words: Opioid, hypogonadism, testosterone, endocrine, androgen


2020 ◽  
Vol 12 (23) ◽  
pp. 10057
Author(s):  
Hyun Hwan Kim ◽  
Mithil Mazumder ◽  
Soon-Jae Lee ◽  
Moon-Sup Lee

In this study, thermoplastic polyurethane (TPU) and styrene-isoprene-styrene (SIS) were utilized to enhance asphalt binder properties. Superpave asphalt binder tests and multiple stress creep recovery (MSCR) were conducted to evaluate the physical and rheological performance (viscosity, rutting, and cracking properties) of the asphalt binders before and after short-term aging and after the long-term aging process. The results showed that (i) TPU has a positive effect on workability, including the mixing and compaction processes, which was evident from the reduced binder viscosity; (ii) asphalt binders with TPU and SIS showed better rutting resistance compared to the SIS binders without TPU; (iii) the cracking resistance of asphalt binders was found to be improved significantly with the addition of TPU; and (iv) TPU has the potential to be considered as a sustainable polymer modifier for producing bearable asphalt binders by improving rutting and crack resistance without increasing the melting temperature of the asphalt binders.


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