scholarly journals Changes over time in young adults’ harmful alcohol consumption: A cross-temporal meta-analysis using the AUDIT

2020 ◽  
Vol 214 ◽  
pp. 108172
Author(s):  
Rachel Visontay ◽  
Louise Mewton ◽  
Matthew Sunderland ◽  
Katrina Prior ◽  
Tim Slade
2019 ◽  
Author(s):  
Rachel Visontay ◽  
Louise Mewton ◽  
Matthew Sunderland ◽  
Katrina Prior ◽  
Tim Slade

Background: Recent studies suggest that young adult participation in, and volume of, alcohol consumption has decreased. However, the evidence on trends in harmful alcohol consumption in this age group is limited. The current paper aims to examine changes over time in harmful alcohol consumption using a robust, widely employed measure.Methods: The literature was systematically searched for articles reporting on Alcohol Use Disorders Identification Test (AUDIT) scores in young adults aged 18-24 years. The key data extracted were year of measurement and mean AUDIT score (proportion above clinical cut-off was not relevant for these analyses). Cross-temporal meta-analysis was applied to the extracted data.Results: A decrease was found in young adults’ AUDIT scores measured between 1989 and 2015 (b=-0.13, β=-0.38, p=0.015, 95% CI=-0.24, -0.03), representing a 0.63 standard deviation change over this period. Variance did not change over this time, suggesting scores decreased equally over the distribution.Conclusions: Results indicate that harmful alcohol consumption in young adults may have declined between 1989 and 2015. Despite the continued problems posed by dependence and short and long-term harms, these promising findings offer hope that the considerable alcohol-related disease burden in this age group may be reduced.Ongoing data collection is required to evaluate whether these declines in young adulthood persist into later life, and future research should explore the reasons for declining harmful alcohol consumption in young adults.


2012 ◽  
Vol 70 (5) ◽  
pp. 1016-1022 ◽  
Author(s):  
Elda L. Fisher ◽  
Rachel Garaas ◽  
George H. Blakey ◽  
Steven Offenbacher ◽  
Daniel A. Shugars ◽  
...  

2009 ◽  
Vol 67 (11) ◽  
pp. 2425-2430 ◽  
Author(s):  
George H. Blakey ◽  
Brent A. Golden ◽  
Raymond P. White ◽  
Steven Offenbacher ◽  
Ceib Phillips ◽  
...  

1991 ◽  
Vol 86 (10) ◽  
pp. 1283-1298 ◽  
Author(s):  
ELIZABETH HARTKA ◽  
BRYAN JOHNSTONE ◽  
E. VICTOR LEINO ◽  
MICHELLE MOTOYOSHI ◽  
MARK T. TEMPLE ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 4805
Author(s):  
Arezo Mokhtary ◽  
Andreas Karakatsanis ◽  
Antonis Valachis

The aim of this meta-analysis was to evaluate the association between mammographic density changes over time and the risk of breast cancer. We performed a systematic literature review based on the PubMed and ISI Web of Knowledge databases. A meta-analysis was conducted by computing extracted hazard ratios (HRs) and 95% confidence intervals (CIs) for cohort studies or odds ratios (ORs) and 95% confidence interval using inverse variance method. Of the nine studies included, five were cohort studies that used HR as a measurement type for their statistical analysis and four were case–control or cohort studies that used OR as a measurement type. Increased breast density over time in cohort studies was associated with higher breast cancer risk (HR: 1.61; 95% CI: 1.33–1.96) whereas decreased breast density over time was associated with lower breast cancer risk (HR: 0.78; 95% CI: 0.71–0.87). Similarly, increased breast density over time was associated with higher breast cancer risk in studies presented ORs (pooled OR: 1.85; 95% CI: 1.29–2.65). Our findings imply that an increase in breast density over time seems to be linked to an increased risk of breast cancer, whereas a decrease in breast density over time seems to be linked to a lower risk of breast cancer.


2014 ◽  
Vol 33 (3) ◽  
pp. 147-154
Author(s):  
António Tralhão ◽  
Pedro Jerónimo Sousa ◽  
António Miguel Ferreira ◽  
Mafalda Miranda ◽  
José Carlos Monge ◽  
...  

2013 ◽  
Vol 43 (9) ◽  
pp. 1857-1868 ◽  
Author(s):  
A. C. Edwards ◽  
K. S. Kendler

BackgroundAlcohol consumption is influenced by genetic factors. Previous studies have examined the heritability of alcohol consumption, or related phenotypes, from adolescence into adulthood, frequently finding that total heritability changes over time. However, it remains unclear whether the same genes underlie liability to alcohol consumption across development versus whether novel risk genes become important over time.MethodA population-based study of adult male twins (n=1790) born in Virginia, USA, retrospectively reported on their average monthly alcohol consumption from early adolescence through adulthood. We used twin modeling methods to explore genetic and environmental influences on alcohol consumption over time.ResultsOne latent genetic factor accounted for the majority of the heritability in alcohol consumption during mid- to late adolescence, but its influence declined thereafter; from young adulthood forward, heritability was largely attributable to a second genetic factor. The total heritability of alcohol consumption increased from 0 at ages 12–14 years to 0.40 by ages 18–21 years. Shared environmental factors declined in influence over time.ConclusionsThe heritability of alcohol consumption over time is dynamic both quantitatively and qualitatively. These results have important implications for gene identification endeavors. Furthermore, these findings could inform efforts to elucidate developmentally dynamic behaviors, such as antisocial behavior.


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