Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure

Of the 1.5 million people diagnosed with pleural effusion in the USA annually, ∼178 000 undergo thoracentesis. While it is known that malignant pleural effusion portends a poor prognosis, mortality of patients with nonmalignant effusions has not been well studied.This prospective cohort study evaluated 308 patients undergoing thoracentesis. Chart review was performed to obtain baseline characteristics. The aetiology of the effusions was determined using standardised criteria. Mortality was determined at 30 days and 1 year.247 unilateral and 61 bilateral thoracenteses were performed. Malignant effusion had the highest 30-day (37%) and 1-year (77%) mortality. There was substantial patient 30-day and 1-year mortality with effusions due to multiple benign aetiologies (29% and 55%), congestive heart failure (22% and 53%), and renal failure (14% and 57%, respectively). Patients with bilateral, relative to unilateral, pleural effusion were associated with higher risk of death at 30 days and 1 year (17% versus 47% (hazard ratio (HR) 2.58, 95% CI 1.44–4.63) and 36% versus 69% (HR 2.32, 95% CI 1.55–3.48), respectively).Patients undergoing thoracentesis for pleural effusion have high short- and long-term mortality. Patients with malignant effusion had the highest mortality followed by multiple benign aetiologies, congestive heart failure and renal failure. Bilateral pleural effusion is distinctly associated with high mortality.

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Right ventricular dysfunction as an independent predictor of short- and long-term mortality in patients with heart failure

European Journal of Heart Failure ◽

10.1016/j.ejheart.2007.03.001 ◽

2007 ◽

Vol 9 (6-7) ◽

pp. 610-616 ◽

Cited By ~ 161

Author(s):

Jesper Kjaergaard ◽

Dilek Akkan ◽

Kasper Karmark Iversen ◽

Lars Køber ◽

Christian Torp-Pedersen ◽

...

Keyword(s):

Heart Failure ◽

Right Ventricular ◽

Ventricular Dysfunction ◽

Independent Predictor ◽

Right Ventricular Dysfunction ◽

Patients With Heart Failure ◽

Short And Long Term ◽

Long Term Mortality

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1138-63 The impact of ejection fraction on long-term mortality after revascularization in patients with congestive heart failure: A report from the BARI trial

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(04)90340-3 ◽

2004 ◽

Vol 43 (5) ◽

pp. A81-A82

Author(s):

Elizabeth M Holper ◽

David P Faxon ◽

Maria Mori Brooks ◽

Lauren J Kim ◽

Katherine M Detre

Keyword(s):

Heart Failure ◽

Congestive Heart Failure ◽

Ejection Fraction ◽

The Impact ◽

Long Term Mortality

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GW28-e0317 Long-term mortality in patients with congestive heart failure treated with cardiac resynchronization therapy

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2017.07.522 ◽

2017 ◽

Vol 70 (16) ◽

pp. C144

Author(s):

Anna Soldatova ◽

Vadim Kuznetsov ◽

Tatyana Enina ◽

Dmitrii Krinochkin ◽

Sergey Dyachkov

Keyword(s):

Heart Failure ◽

Congestive Heart Failure ◽

Cardiac Resynchronization Therapy ◽

Cardiac Resynchronization ◽

Resynchronization Therapy ◽

Long Term Mortality

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Epidemiology of Major Lower Extremity Amputations in Individuals With Diabetes in Austria, 2014-2017: A Retrospective Analysis of Health Insurance Database

10.21203/rs.3.rs-36835/v1 ◽

2020 ◽

Author(s):

Faisal Aziz ◽

Berthold Reichardt ◽

Caren Sourij ◽

Hans-Peter Dimai ◽

Daniela Reichart ◽

...

Keyword(s):

Risk Factors ◽

Heart Failure ◽

Health Insurance ◽

Lower Extremity ◽

Renal Disease ◽

Mortality Rates ◽

Short And Long Term ◽

Male Sex ◽

Long Term Mortality

Abstract Background: Previous data show a high incidence of major lower extremity amputations (LEA) in Austria. Moreover, recent data on the epidemiology of major LEA are sparse in the Country. This study estimated the incidence and mortality rates of major LEA and assessed risk factors of post major LEA mortality in individuals with diabetes.Methods: A retrospective cohort analysis of 507,180 individuals with diabetes enrolled in the Austrian Health Insurance between 2014 and 2017 was performed. Crude and age-standardized rates of major LEA (hip, femur, knee, lower leg) were estimated by extracting their procedure codes from the database. Short- (30-day, 90-day) and long-term (1-year, 5-year) all-cause cumulative mortality after major LEA was estimated from the date of amputation till the date of death. Poisson regression was performed to compare rates by characteristics and assess the annual trend. The Cox-regression was performed to identify significant risk factors of all-cause mortality after major LEA.Results: A total of 2,165 individuals with diabetes underwent major LEA between 2014 and 2017. The mean age was amputees was 73.0 ±11.3 years, 62.7% were males, and 87.3% had a peripheral vascular disease (PVD). The overall age-standardized rate was 6.44 per 100,000 population. The rate increased with age (p<0.001) and was higher (p<0.001) in males (9.38) than females (5.66). The rate was 5.71 in 2014, 6.86 in 2015, 6.71 in 2016, and 6.66 in 2017, with an insignificant annual change of 3% (p=0.825). The cumulative 30-day mortality was 13.5%, 90-day was 22.0%, 1-year was 34.4%, and 5-year was 66.7%. Age, male sex, above-knee amputation, Charlson index, and heart failure were significantly associated with both short- and long-term mortality. Cancer, dementia, heart failure, PVD, and renal disease were only associated with long-term mortality.Conclusions: The rate of major LEA remained stable between 2014 and 2017 in Austria. Short and long-term mortality rates were considerably high after major LEA. Old age, male sex, above-knee amputations, heart failure, and Charlson Index were significant predictors of both short- and long-term mortality, whereas, comorbidities such as cancer, dementia, PVD, and renal disease were significant predictors of long-term mortality only.

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