scholarly journals Associations of exposure to residential green space and neighborhood walkability with coronary atherosclerosis in Chinese adults

2022 ◽  
Vol 292 ◽  
pp. 118347
Author(s):  
Hai-Bo Hu ◽  
Zhi-Hui Hou ◽  
Cong-Hong Huang ◽  
Michael J. LaMonte ◽  
Meng Wang ◽  
...  
2021 ◽  
Author(s):  
Lin Yang ◽  
Ka Long Chan ◽  
John Yuen ◽  
Frances K.Y. Wong ◽  
Lefei Han ◽  
...  

BACKGROUND Health benefits of urban green space have been widely reported in literature, but the biological mechanisms remain unexplored and a causal relationship cannot be established between green space exposure and cardiorespiratory health. OBJECTIVE We conducted a panel study using personal tracking devices to continuously collect the individual exposure data in healthy Chinese adults aged 50 to 64 years living in Hong Kong. METHODS A panel of cardiorespiratory biomarkers were tested each week for a period of consecutive five weeks. Weekly exposure to green space, air pollution and physical activities of individual participants was collected by personal tracking devices. The effects of green space exposure measured by the Normalized Difference Vegetation Index (NDVI) at the buffer zones of 100-, 250- and 500-meters on a panel of cardiorespiratory biomarkers were estimated by a generalized linear mixed-effects model, with adjustment for confounding variables of sociodemographic characteristics, exposure to air pollutants and noise, exercises and nutrient intakes. RESULTS A total of 39 participants (mean age 56.4 years, range 50-63 years) were recruited and followed up for five consecutive weeks. After adjustment for sex, income, occupation, physical activities, dietary intake, noise and air pollution, significant negative associations with the 250m-buffer NDVI were found in total cholesterol (-21.6% per IQR increase in NDVI, 95% confidence interval (CI) -32.7%, -10.6%), low-density lipoprotein (LDL-C) (-14.9%, 95% CI -23.4%, -6.4%), glucose (-11.2%, 95% CI -21.9%, -0.5%) and high-sensitivity C-reactive protein (hs-CRP) (-41.3%, 95% CI -81.7%, -0.9%). Similar effect estimates were found for the 100m- and 250m-buffer. After adjustment for multiple testing, the effect estimates of glucose and hs-CRP were no longer significant. CONCLUSIONS Health benefits of green space can be found in some metabolic and inflammatory biomarkers. Further studies are warranted to establish the causal relationship of green space and cardiorespiratory health. CLINICALTRIAL


2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Lizan D. Bloemsma ◽  
Dana Dabelea ◽  
Yuying Ren ◽  
David Rojas Rueda ◽  
Colleen E. Reid ◽  
...  

2017 ◽  
Vol 235 ◽  
pp. 118-123 ◽  
Author(s):  
Lin Ding ◽  
Kui Peng ◽  
Lin Lin ◽  
Mian Li ◽  
Tiange Wang ◽  
...  

1995 ◽  
Vol 73 (03) ◽  
pp. 374-379 ◽  
Author(s):  
Jürgen Heinrich ◽  
Helmut Schulte ◽  
Rainer Schönfeld ◽  
Ekkehart Köhler ◽  
Gerd Assmann

SummaryWe investigated the vessel status of coronary and peripheral arteries and those arteries supplying the brain in 929 consecutive male patients admitted to a coronary rehabilitation unit. The severity of coronary atherosclerosis was scored using coronary angiography. Changes in extracranial brain vessels and manifest cerebrovascular disease (CVD) were determined by B-mode ultrasound and Doppler examination. Peripheral arterial disease (PAD) was diagnosed using base-line and stress oscillography. We assessed variables of coagulation, fibrinolysis, and the acute phase response.There was a significant increase in plasma fibrinogen, plasminogen, d-dimer and C-reactive protein (CRP) with increasing severity of coronary heart disease. Compared to men with unaffected arteries, men with 3 diseased coronary arteries had 58% greater d-dimer concentrations. Patients with CVD and PAD, respectively, also had significantly higher fibrinogen, d-dimer and CRP concentrations. We did not find an association between plasminogen activator inhibitor activity and the severity of coronary atherosclerosis.In conclusion, plasma fibrinogen, d-dimer and CRP concentrations were significantly related to atherosclerosis in the coronary, peripheral and extracranial brain arteries.


2005 ◽  
Vol 53 (S 01) ◽  
Author(s):  
O Grauhan ◽  
H Chang ◽  
R Meyer ◽  
N Hiemann ◽  
W Albert ◽  
...  

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