Electrospun antibacterial polyacrylonitrile nanofiber membranes functionalized with silver nanoparticles by a facile wetting method

The composite nanofiber membranes of poly (ε-caprolactone)/poly(vinyl pyrrolidone) (PCL/PVP) containing silver nanoparticles were prepared by electrospinning method. The morphology of composite nanofibers was characterized by scanning electron microscopy (SEM). The silver nanoparticles on the electrospun fibers were characterized by X-Ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The contact angle and water uptake of PCL/PVP/Ag nanofiber membranes were measured. The SEM photos indicated that the average diameter of the fibers was significantly decreased with the addition of silver nanoparticles. The X-Ray images showed that Ag nanoparticles were distributed on the surface of nanofiber membranes. When the PVP mole ratio was higher than 15%, the nanofiber membranes showed good hydrophilic property. The PCL/PVP/Ag nanofiber membranes could be applied to prepare wound dressing.

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Fabrication, Characterization, and Antibacterial Properties of Electrospun Membrane Composed of Gum Karaya, Polyvinyl Alcohol, and Silver Nanoparticles

Journal of Nanomaterials ◽

10.1155/2015/750726 ◽

2015 ◽

Vol 2015 ◽

pp. 1-10 ◽

Cited By ~ 14

Author(s):

Vinod Vellora Thekkae Padil ◽

Nhung H. A. Nguyen ◽

Alena Ševců ◽

Miroslav Černík

Keyword(s):

Electron Microscopy ◽

Silver Nanoparticles ◽

Polyvinyl Alcohol ◽

Food Packaging ◽

Chemical Reduction ◽

Antibacterial Properties ◽

Hydroxyl Groups ◽

Ag Nps ◽

Gum Karaya ◽

Nanofiber Membranes

Gum karaya (GK), a natural hydrocolloid, was mixed with polyvinyl alcohol (PVA) at different weight ratios and electrospun to produce PVA/GK nanofibers. An 80 : 20 PVA/GK ratio produced the most suitable nanofiber for further testing. Silver nanoparticles (Ag-NPs) were synthesised through chemical reduction of AgNO3(at different concentrations) in the PVA/GK solution, the GK hydroxyl groups being oxidised to carbonyl groups, and Ag+cations reduced to metallic Ag-NPs. These PVA/GK/Ag solutions were then electrospun to produce nanofiber membranes containing Ag-NPs (Ag-MEMs). Membrane morphology and other characteristics were analysed using scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, and UV-Vis and ATR-FTIR spectroscopy. The antibacterial activity of the Ag-NP solution and Ag-MEM was then investigated against Gram-negativeEscherichia coliandPseudomonas aeruginosaand Gram-positiveStaphylococcus aureus. Our results show that electrospun nanofiber membranes based on natural hydrocolloid, synthetic polymer, and Ag-NPs have many potential uses in medical applications, food packaging, and water treatment.

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Functional Hyaluronic Acid-Polylactic Acid/Silver Nanoparticles Core-Sheath Nanofiber Membranes for Prevention of Post-Operative Tendon Adhesion

International Journal of Molecular Sciences ◽

10.3390/ijms22168781 ◽

2021 ◽

Vol 22 (16) ◽

pp. 8781

Author(s):

Chih-Hao Chen ◽

Yuan-Hsun Cheng ◽

Shih-Heng Chen ◽

Andy Deng-Chi Chuang ◽

Jyh-Ping Chen

Keyword(s):

Silver Nanoparticles ◽

Hyaluronic Acid ◽

Polylactic Acid ◽

In Vivo Studies ◽

Ag Nps ◽

Barrier Membranes ◽

The Core ◽

Fibroblast Attachment ◽

Nanofiber Membranes ◽

Anti Inflammatory

In this study, we prepared core-sheath nanofiber membranes (CSNFMs) with silver nanoparticles (Ag NPs) embedding in the polylactic acid (PLA) nanofiber sheath and hyaluronic acid (HA) in the nanofiber core. The PLA/Ag NPs sheath provides mechanical support as well as anti-bacterial and anti-inflammatory properties. The controlled release of HA from the core could exert anti-adhesion effects to promote tendon sliding while reducing fibroblast attachment. From the microfibrous structural nature of CSNFMs, they function as barrier membranes to reduce fibroblast penetration without hampering nutrient transports to prevent post-operative peritendinous adhesion. As the anti-adhesion efficacy will depend on release rate of HA from the core as well as Ag NP from the sheath, we fabricated CSNFMs of comparable fiber diameter, but with thick (Tk) or thin (Tn) sheath. Similar CSNFMs with thick (Tk+) and thin (Tn+) sheath but with embedded Ag NPs in the sheath were also prepared. The physico-chemical properties of the barrier membranes were characterized in details, together with their biological response including cell penetration, cell attachment and proliferation, and cytotoxicity. Peritendinous anti-adhesion models in rabbits were used to test the efficacy of CSNFMs as anti-adhesion barriers, from gross observation, histology, and biomechanical tests. Overall, the CSNFM with thin-sheath and Ag NPs (Tn+) shows antibacterial activity with low cytotoxicity, prevents fibroblast penetration, and exerts the highest efficacy in reducing fibroblast attachment in vitro. From in vivo studies, the Tn+ membrane also shows significant improvement in preventing peritendinous adhesions as well as anti-inflammatory efficacy, compared with Tk and Tn CSNFMs and a commercial adhesion barrier film (SurgiWrap®) made from PLA.

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Catalytic and antibacterial activities of green-synthesized silver nanoparticles on electrospun polystyrene nanofiber membranes using tea polyphenols

Composites Part B Engineering ◽

10.1016/j.compositesb.2015.04.037 ◽

2015 ◽

Vol 79 ◽

pp. 217-223 ◽

Cited By ~ 37

Author(s):

Zhenyan Liu ◽

Jiajie Yan ◽

Yue-E Miao ◽

Yunpeng Huang ◽

Tianxi Liu

Keyword(s):

Silver Nanoparticles ◽

Antibacterial Activities ◽

Tea Polyphenols ◽

Nanofiber Membranes ◽

Green Synthesized Silver Nanoparticles

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Electrospun nanofibers of poly (acrylonitrile-co-itaconic acid)/silver and polyacrylonitrile/silver: In situ preparation, characterization, and antimicrobial activity

Journal of Industrial Textiles ◽

10.1177/1528083719868170 ◽

2019 ◽

pp. 152808371986817

Author(s):

Havva Baskan ◽

Imren Esentürk ◽

Sibel Dösler ◽

A Sezai Sarac ◽

Hale Karakas

Keyword(s):

Silver Nanoparticles ◽

Itaconic Acid ◽

Electrospun Nanofibers ◽

Antimicrobial Activities ◽

E Coli ◽

In Situ Preparation ◽

Thermal Features ◽

Nanofiber Membranes ◽

Poly Acrylonitrile

In this study, it was aimed to prepare silver nanoparticles by reduction of silver salt (AgNO3) in situ by means of only synthesized polyacrylonitrile (PAN) and poly(acrylonitrile-co-itaconic acid) (P(AN-co-IA)) polymers, and N,N dimethylformamide (DMF). Thereafter, PAN/Ag and P(AN-co-IA)/Ag nanofibers were prepared via electrospinning. Spectroscopic and morphologic characterizations, electrical and thermal features, and antimicrobial activities of the prepared nanofibers against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans were carried out in detail. It was observed that P(AN-co-IA) was much more effective than PAN on the reduction of AgNO3 and formation of silver nanoparticles. Silver nanoparticles and also itaconic acid contributed to decrease the cyclization temperature of PAN by generating sharp exothermic peaks. In addition, electrical conductivity of the nanofibers increased dramatically from E−13 to E−4 related to the presence of silver nanoparticles. Furthermore, incorporation of silver nanoparticles to the nanofiber membranes let bactericidal/fungicidal activities, which started at 6–24 h and continued for up to 168 h, against S. aureus, E. coli, P. aeruginosa, and C. albicans. The prepared silver containing nanofibers can be regarded as good candidates for potential use in the biomedical and pharmaceutical applications.

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Synthesis, performance and growth mechanism of silver nanoparticle coated SERS fiber probe

Matériaux & Techniques ◽

10.1051/mattech/2018061 ◽

2019 ◽

Vol 107 (3) ◽

pp. 305

Author(s):

Mengmei Geng ◽

Yuting Long ◽

Tongqing Liu ◽

Zijuan Du ◽

Hong Li ◽

...

Keyword(s):

Silver Nanoparticles ◽

Absorption Spectrum ◽

Reaction Time ◽

Growth Mechanism ◽

Fiber Optic ◽

Fiber Optic Probe ◽

Visible Absorption ◽

Fiber Probe ◽

Surface Enhanced Raman ◽

Optic Probe

Surface-enhanced Raman Scattering (SERS) fiber probe provides abundant interaction area between light and materials, permits detection within limited space and is especially useful for remote or in situ detection. A silver decorated SERS fiber optic probe was prepared by hydrothermal method. This method manages to accomplish the growth of silver nanoparticles and its adherence on fiber optic tip within one step, simplifying the synthetic procedure. The effects of reaction time on phase composition, surface plasmon resonance property and morphology were investigated by X-ray diffraction analysis (XRD), ultraviolet-visible absorption spectrum (UV-VIS absorption spectrum) and scanning electron microscope (SEM). The results showed that when reaction time is prolonged from 4–8 hours at 180 °C, crystals size and size distribution of silver nanoparticles increase. Furthermore, the morphology, crystal size and distribution density of silver nanoparticles evolve along with reaction time. A growth mechanism based on two factors, equilibrium between nucleation and growth, and the existence of PVP, is hypothesized. The SERS fiber probe can detect rhodamin 6G (R6G) at the concentration of 10−6 M. This SERS fiber probe exhibits promising potential in organic dye and pesticide residue detection.

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