Hydrophobic peptides from oyster protein hydrolysates show better zinc-chelating ability

2021 ◽  
Vol 41 ◽  
pp. 100985
Author(s):  
Ziye Wang ◽  
Shuzhen Cheng ◽  
Di Wu ◽  
Zhe Xu ◽  
Shiqi Xu ◽  
...  
Author(s):  
Beverly E. Maleeff ◽  
Timothy K. Hart ◽  
Stephen J. Wood ◽  
Ronald Wetzel

Alzheimer's disease is characterized post-mortem in part by abnormal extracellular neuritic plaques found in brain tissue. There appears to be a correlation between the severity of Alzheimer's dementia in vivo and the number of plaques found in particular areas of the brain. These plaques are known to be the deposition sites of fibrils of the protein β-amyloid. It is thought that if the assembly of these plaques could be inhibited, the severity of the disease would be decreased. The peptide fragment Aβ, a precursor of the p-amyloid protein, has a 40 amino acid sequence, and has been shown to be toxic to neuronal cells in culture after an aging process of several days. This toxicity corresponds to the kinetics of in vitro amyloid fibril formation. In this study, we report the biochemical and ultrastructural effects of pH and the inhibitory agent hexadecyl-N-methylpiperidinium (HMP) bromide, one of a class of ionic micellar detergents known to be capable of solubilizing hydrophobic peptides, on the in vitro assembly of the peptide fragment Aβ.


1949 ◽  
Vol 12 (4) ◽  
pp. 586-596 ◽  
Author(s):  
Mitchell Zweig ◽  
Karl A. Meyer ◽  
Frederick Steigmann
Keyword(s):  

2003 ◽  
Vol 32 (2) ◽  
pp. 193-204 ◽  
Author(s):  
B. Wróblewska ◽  
M. Karamać

2012 ◽  
Vol 35 (7) ◽  
pp. 1113-1119 ◽  
Author(s):  
Kai-feng LI ◽  
Yong-kang LUO ◽  
Qi-chao FENG ◽  
Lei YAO

2010 ◽  
Vol 15 (4) ◽  
pp. 282-286 ◽  
Author(s):  
So-Jeong Jeon ◽  
Ji-Hye Lee ◽  
Kyung-Bin Song

Marine Drugs ◽  
2021 ◽  
Vol 19 (7) ◽  
pp. 377
Author(s):  
Bomi Ryu ◽  
Kyung-Hoon Shin ◽  
Se-Kwon Kim

Fish muscle, which accounts for 15%–25% of the total protein in fish, is a desirable protein source. Their hydrolysate is in high demand nutritionally as a functional food and thus has high potential added value. The hydrolysate contains physiologically active amino acids and various essential nutrients, the contents of which depend on the source of protein, protease, hydrolysis method, hydrolysis conditions, and degree of hydrolysis. Therefore, it can be utilized for various industrial applications including use in nutraceuticals and pharmaceuticals to help improve the health of humans. This review discusses muscle protein hydrolysates generated from the muscles of various fish species, as well as their amino acid composition, and highlights their functional properties and bioactivity. In addition, the role of the amino acid profile in regulating the biological and physiological activities, nutrition, and bitter taste of hydrolysates is discussed.


2021 ◽  
pp. 2100139
Author(s):  
Ivan Cruz‐Chamorro ◽  
Nuria Álvarez‐Sánchez ◽  
Ana Isabel Álvarez‐Ríos ◽  
Guillermo Santos‐Sánchez ◽  
Justo Pedroche ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document