Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation

Atherosclerosis is a pro-oxidative and pro-inflammatory disease state, which is the underlying cause of most cardiovascular events, estimated to affect 5.2% of the Australian population. Diet, and specifically vitamin C, through its antioxidant properties can play a role in impeding the development and progression of atherosclerosis. This systematic review conducted comprehensive searches in Medline, Emcare, Scopus, PubMed, and Cochrane using key search terms for vitamin C, plasma vitamin C, supplementation, and cardiovascular disease (CVD). The results demonstrated that vitamin C supplementation resulted in a significant increase in vitamin C levels in populations with or without CVD, except for one study on the CVD population. It was also seen that the healthy population baseline and post-intervention vitamin C levels were high compared to the CVD population. However, further research is indicated for CVD population groups with varying baseline vitamin C levels, such as low baseline vitamin C, within a more representative elderly cohort in order to formulate and update vitamin C repletion guidelines.

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Effect of vitamin E intake from food and supplement sources on plasma α- and γ-tocopherol concentrations in a healthy Irish adult population

British Journal Of Nutrition ◽

10.1017/s0007114514002438 ◽

2014 ◽

Vol 112 (9) ◽

pp. 1575-1585 ◽

Cited By ~ 20

Author(s):

Yang Zhao ◽

Frank J. Monahan ◽

Breige A. McNulty ◽

Mike J. Gibney ◽

Eileen R. Gibney

Keyword(s):

Vitamin E ◽

Adult Population ◽

Plasma Concentrations ◽

Fats And Oils ◽

Food Sources ◽

Dietary Vitamin ◽

Plasma Vitamin ◽

Institute Of Medicine ◽

Nutrition Survey ◽

Plasma Vitamin E

Vitamin E is believed to play a preventive role in diseases associated with oxidative stress. The aims of the present study were to quantify vitamin E intake levels and plasma concentrations and to assess dietary vitamin E adequacy in Irish adults. Intake data from the National Adult Nutrition Survey were used; plasma samples were obtained from a representative cohort of survey participants. Plasma α- and γ-tocopherol concentrations were measured by HPLC. The main sources of vitamin E in the diet were ‘butter, spreadable fats and oils’ and ‘vegetables and vegetable dishes’. When vitamin E intake from supplements was taken into account, supplements were found to be the main contributor, making a contribution of 29·2 % to vitamin E intake in the total population. Supplement consumers had significantly higher plasma α-tocopherol concentrations and lower plasma γ-tocopherol concentrations when compared with non-consumers. Consumers of ‘vitamin E’ supplements had significantly higher vitamin E intake levels and plasma α-tocopherol concentrations compared with consumers of other types of supplements, such as multivitamin and fish oil. Comparison with the Institute of Medicine Estimated Average Requirement of 12 mg/d indicated that when vitamin E intake from food and supplement sources was taken into account, 100 % of the study participants achieved the recommended intake levels. When vitamin E intake from food sources was taken into account, only 68·4 % of the females were found to achieve the recommended intake levels compared with 99·2 % of the males. The results of the present study show that dietary vitamin E intake has a significant effect on plasma α- and γ-tocopherol concentrations. Furthermore, they show that the consumption of supplements is a major contributor to overall intake and has a significant effect on plasma vitamin E concentrations in the Irish population.

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Feeding concentrate pellets enriched by natural vitamin E keeps the plasma vitamin E above the critical level in calves post-weaning

Livestock Science ◽

10.1016/j.livsci.2021.104672 ◽

2021 ◽

pp. 104672

Author(s):

Saman Lashkari ◽

Søren K. Jensen ◽

Christina B. Hansen ◽

Kenneth Krogh ◽

Per Theilgaard ◽

...

Keyword(s):

Vitamin E ◽

Critical Level ◽

Plasma Vitamin ◽

Natural Vitamin ◽

Plasma Vitamin E

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Study on oxidative stress and antioxidant level in patients of acute myocardial infarction before and after regular treatment

Bangladesh Medical Research Council Bulletin ◽

10.3329/bmrcb.v40i2.25226 ◽

2015 ◽

Vol 40 (2) ◽

pp. 79-84 ◽

Cited By ~ 10

Author(s):

T Bashar ◽

N Akhter

Keyword(s):

Oxidative Stress ◽

Risk Factors ◽

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Vitamin E ◽

Plasma Vitamin ◽

Regular Treatment ◽

Before And After ◽

The Difference ◽

Plasma Vitamin E

In acute myocardial infarction (AMI), lack of oxygen delivery to myocardium leads to generation of reactive oxygen species (ROS) which play an important role in the pathogenesis of AMI. Endogenous anti-oxidants protect the myocardial tissues from the deleterious effect of free radical mediate injury. The study evaluates the extent of oxidative stress and antioxidant status against ROS in AMI patients and amelioration of oxidative stress after regular treatment and also assesses the association between oxidative stress and risk factors for atherosclerosis like dyslipidemia and diabetes mellitus (DM).The study was conducted on 72 AMI patients and age and sex matched 18 healthy controls. Patients were assigned to four groups, AMI without dyslipidemia or DM, with dyslipidemia, with DM and with both dyslipidemia and DM. Plasma malondialdehyde (MDA) and GSH content and vitamin E levels were determined on admission into hospital and on the 5th day of treatment. Plasma MDA level increased significantly (p<0.001) and erythrocyte GSH and plasma vitamin E levels were decreased (p<0.001) in all the groups of patients as compared to control. On the 5th day of regular treatment MDA level reduced (p<0.001) and GSH and vitamin E levels increased (p<0.001) in patients. The plasma MDA level was significantly higher (p<0.001) in patients with both dyslipidemia and DM or with only DM in comparison to patients without dyslipidemia and DM. The difference in the GSH level between patients with risk factors and without risk factors was not significant. It may be conclude that an imbalance exists between oxidant and antioxidant molecules in AMI patients which shift towards oxidative side and regular treatment restores this balance. There may be some association between oxidative stress in AMI and risk factors like dyslipidemia and diabetes mellitus.Bangladesh Med Res Counc Bull 2014; 40 (2): 79-84

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Plasma vitamin E and beta-carotene concentrations during radiochemotherapy preceding bone marrow transplantation

American Journal of Clinical Nutrition ◽

10.1093/ajcn/51.2.216 ◽

1990 ◽

Vol 51 (2) ◽

pp. 216-219 ◽

Cited By ~ 55

Author(s):

M R Clemens ◽

C Ladner ◽

G Ehninger ◽

H Einsele ◽

W Renn ◽

...

Keyword(s):

Bone Marrow ◽

Vitamin E ◽

Bone Marrow Transplantation ◽

Marrow Transplantation ◽

Beta Carotene ◽

Plasma Vitamin ◽

Plasma Vitamin E

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The early anaemia of the premature infant: is there a place for vitamin E supplementation?

British Journal Of Nutrition ◽

10.1079/bjn19860090 ◽

1986 ◽

Vol 56 (1) ◽

pp. 105-114 ◽

Cited By ~ 7

Author(s):

S. P. Conway ◽

I Rawson ◽

P. R. F. Dear ◽

S. E. Shires ◽

J. Kelleher

Keyword(s):

Vitamin E ◽

Premature Infant ◽

Premature Baby ◽

Oral Feeding ◽

Plasma Vitamin ◽

Double Blind ◽

Plasma Vitamin E ◽

Sufficient Vitamin ◽

Vitamin E Supplementation

1. The efficacy of oral vitamin E supplementation in preventing the early anaemia of the premature infant was assessed in a 10-week double-blind trial. Forty-two babies received either a placebo or 5 or 15 mg supplementary vitamin E/d with oral feeding. No infant received less than the recommended vitamin E:polyunsaturated fatty acid (E:PUFA) value of 0.6. No iron supplement was given.2. Weekly full blood counts were taken, and plasma vitamin E assay and in vitro haemolysis tests performed on blood sampled on day 1, and also at 6 and 10 weeks of age. All blood withdrawn and transfused and all feeds were documented.3. Thirty-six (86%) of the babies had a plasma vitamin E level at birth below the accepted adult norm, i.e. < 5200 μg/l. At 6 weeks of age thirty-three (79%) and at 10 weeks thirty-five (83%) of the babies had levels within the normal adult range. No baby showed either clinical or haematological evidence of a vitamin E deficiency state during the trial.4. It is concluded that in the absence of Fe supplementation and observing the minimum recommended E:PUFA value, contemporary feeding practices allow for the absorption of sufficient vitamin E by the premature baby to prevent the development of an early haemolytic anaemia.5. No significant relation was found between plasma vitamin E levels and the degree of peroxide haemolysis.

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