Sensitive bowel syndrome better than irritable bowel syndrome

2018 ◽  
Vol 41 (4) ◽  
pp. 292
Author(s):  
Juan J. Sebastián Domingo
Keyword(s):  
Irritable Bowel Syndrome ◽  
Irritable Bowel ◽  
Better Than

scholarly journals Comparison of Electroacupuncture and Moxibustion for Relieving Visceral Hypersensitivity in Rats with Constipation-Predominant Irritable Bowel Syndrome

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Ji-Meng Zhao ◽  
Liu Chen ◽  
Ci-Li Zhou ◽  
Yin Shi ◽  
Yu-Wei Li ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Visceral Hypersensitivity ◽  
Receptor Expression ◽  
Blue Staining ◽  
Toluidine Blue Staining ◽  
Treatment Groups ◽  
Analgesic Effects ◽  
Colorectal Distention ◽  
Irritable Bowel ◽  
Better Than

Aim. To compare whether there is different effect between electroacupuncture (EA) and moxibustion (Mox) on visceral hypersensitivity (their analgesic effects) in constipation-predominant irritable bowel syndrome (C-IBS).Methods. EA at 1 mA and 3 mA and Mox at 43°C and 46°C were applied to the Shangjuxu (ST37, bilateral) acupoint in rats with C-IBS and normal rats. An abdominal withdrawal reflex (AWR) score was used to assess visceral hypersensitivity. Toluidine blue staining was used to assess mast cell (MC) activity in colon of rats. Immunochemistry was used to measure 5-HT and 5-HT4 receptor expression in the colon.Results. AWR scores in all EA (1 mA and 3 mA) and Mox (43°C and 46°C) treatment groups after colorectal distention (CRD) stimulation pressure of 20, 40, 60, and 80 mmHg were significantly lower than those of the model (MC) group (Pall < 0.01). The MC counts and degranulation rates in the colon of all EA and Mox treatment groups and the MC group were significantly higher than those of the NC group (Pall < 0.01). MC degranulation rates in the colon of all EA and Mox treatment groups were lower than those of the MC group (Pall < 0.05). 5-HT expression in colon of all EA and Mox treatment groups was significantly lower than that of the MC group (Pall < 0.01), and 5-HT4R expression in colon of both EA groups was significantly higher than that of the MC group (Pboth < 0.01).Conclusion. EA and Mox treatments may both ameliorate visceral hypersensitivity at different degree in rats with C-IBS, and EA treatment was better than Mox.

scholarly journals Effect of acupuncture combined with Astragalus injection on peripheral blood inflammatory factors in children with diarrhea-predominant irritable bowel syndrome

2019 ◽  
Vol 17 ◽  
pp. 205873921985368 ◽  
Author(s):  
Huimin Xue ◽  
Shan Shao
Keyword(s):  
Irritable Bowel Syndrome ◽  
Acupuncture Therapy ◽  
Peripheral Blood ◽  
Inflammatory Factors ◽  
Control Group ◽  
Therapeutic Effects ◽  
Study Group ◽  
Calcitonin Gene ◽  
Irritable Bowel ◽  
Better Than

The objective of this article is to explore the clinical efficacy of acupuncture therapy of Traditional Chinese Medicine (TCM) combined with Astragalus injection in the treatment of children with diarrhea-predominant irritable bowel syndrome (IBS), and its effects on 5-hydroxytryptamine (5-HT), neuropeptide Y (NPY), and calcitonin gene-related peptide (CGRP) in peripheral blood. A total of 116 children with diarrhea-predominant IBS admitted to our hospital from January 2017 to January 2018 were randomly divided into two groups. The control group was treated with Astragalus injection, while the research group was treated with acupuncture therapy of TCM combined with Astragalus injection. The therapeutic effects, the concentrations of CGRP, NPY, and 5-HT in peripheral blood were compared between the two groups. The therapeutic efficacy of the study group was better than that of the control group ( P < 0.05). The concentrations of CGRP, NPY, and 5-HT in the peripheral blood of the study group were less than those of the control group ( P < 0.05). Acupuncture therapy of TCM combined with Astragalus injection has a satisfactory effect in the treatment of children with diarrhea-predominant IBS, which is worthy of more publicity and application in the clinic.

scholarly journals Acupuncture for Diarrhoea-Predominant Irritable Bowel Syndrome: A Network Meta-Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Lingping Zhu ◽  
Yunhui Ma ◽  
Shasha Ye ◽  
Zhiqun Shu
Keyword(s):  
Irritable Bowel Syndrome ◽  
Side Effects ◽  
Data Extraction ◽  
Meta Analysis ◽  
Sham Acupuncture ◽  
Cochrane Library ◽  
Highly Qualified ◽  
Pinaverium Bromide ◽  
Irritable Bowel ◽  
Better Than

Background. The objective of this study was to compare the efficacy and side effects of acupuncture, sham acupuncture, and drugs in the treatment of diarrhoea-predominant irritable bowel syndrome. Methods. Randomized controlled trials (RCTs) assessing the effects of acupuncture and drugs were comprehensively retrieved from electronic databases (such as PubMed, Cochrane Library, Embase, CNKI, Wanfang Database, VIP Database, and CBM) up to December 2017. Additional references were obtained from review articles. With document quality evaluations and data extraction, Network Meta-Analysis was performed using a random-effects model under a frequentist framework. Results. A total of 29 studies (n = 9369) were included; 19 were high-quality studies, and 10 were low-quality studies. NMA showed the following: (1) the ranking of treatments in terms of efficacy in diarrhoea-predominant irritable bowel syndrome is acupuncture, sham acupuncture, pinaverium bromide, alosetron = eluxadoline, ramosetron, and rifaximin; (2) the ranking of treatments in terms of severity of side effects in diarrhoea-predominant irritable bowel syndrome is rifaximin, alosetron, ramosetron = pinaverium bromide, sham acupuncture, and acupuncture; and (3) the treatment of diarrhoea-predominant irritable bowel syndrome includes common acupoints such as ST25, ST36, ST37, SP6, GV20, and EX-HN3. Conclusion. Acupuncture may improve diarrhoea-predominant irritable bowel syndrome better than drugs and has the fewest side effects. Sham acupuncture may have curative effect except for placebo effect. In the future, it is necessary to perform highly qualified research to prove this result. Pinaverium bromide also has good curative effects with fewer side effects than other drugs.

scholarly journals The fecal mycobiome in patients with Irritable Bowel Syndrome

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
A. Das ◽  
E. O’Herlihy ◽  
F. Shanahan ◽  
P. W. O’Toole ◽  
I. B. Jeffery
Keyword(s):  
Irritable Bowel Syndrome ◽  
Dietary Habits ◽  
Bile Acid Malabsorption ◽  
Operational Taxonomic Units ◽  
Control Subjects ◽  
Diagnostic Potential ◽  
Unknown Species ◽  
Irritable Bowel ◽  
And Control ◽  
Better Than

AbstractAlterations of the gut microbiota have been reported in various gastrointestinal disorders, but knowledge of the mycobiome is limited. We investigated the gut mycobiome of 80 patients with Irritable Bowel Syndrome (IBS) in comparison with 64 control subjects. The fungal-specific internal transcribed spacer 1 (ITS-1) amplicon was sequenced, and mycobiome zero-radius operational taxonomic units (zOTUs) were defined representing known and unknown species and strains. The fungal community was sparse and individual-specific in all (both IBS and control) subjects. Although beta-diversity differed significantly between IBS and controls, no difference was found among clinical subtypes of IBS or in comparison with the mycobiome of subjects with bile acid malabsorption (BAM), a condition which may overlap with IBS with diarrhoea. The mycobiome alterations co-varied significantly with the bacteriome and metabolome but were not linked with dietary habits. As a putative biomarker of IBS, the predictive power of the fecal mycobiome in machine learning models was significantly better than random but insufficient for clinical diagnosis. The mycobiome presents limited therapeutic and diagnostic potential for IBS, despite co-variation with bacterial components which do offer such potential.

Motor and sensory function of the rectum in different types of irritable bowel syndrome

2001 ◽  
Vol 120 (5) ◽  
pp. A399-A399
Author(s):  
J STEENS ◽  
P SCHAAR ◽  
C LAMERS ◽  
A MASCLEE
Keyword(s):  
Irritable Bowel Syndrome ◽  
Sensory Function ◽  
Different Types ◽  
Irritable Bowel
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