This article provides a review of the literature on coronary heart disease, namely stable angina pectoris – one of the forms of chronic coronary heart disease. The role of CHD in mortality and disability of the population is considered. The literature review describes the etiology, risk factors, classification, pathogenetic nature of the disease, diagnostic methods, and also addresses issues of treatment and medical and labor expertise that are relevant today. The importance of subjective and objective methods of examination along with highly informative laboratory and instrumental methods currently being introduced is noted. A fundamental step towards eliminating risk factors is lifestyle modification. Of particular relevance is the issue of drug treatment of stable angina pectoris, the main purpose of which is to reduce the symptoms of angina pectoris and prevent cardiovascular complications. The article presents data from clinical studies examining the effectiveness of modern antianginal, antithrombotic, lipid-lowering therapy. The data on the possibility of using the valsartan and sacubitril complex in order to reduce the risk of hospitalization and death in the presence of symptomatic CHF (LVEF ≤ 35%) are presented.
Serum Fas/FasL levels in dependence on clinical presentations of coronary disease and their relationship with risk factors
