scholarly journals High-resolution imaging in Barrett's esophagus: a novel, low-cost endoscopic microscope

2008 ◽  
Vol 68 (4) ◽  
pp. 737-744 ◽  
Author(s):  
Timothy J. Muldoon ◽  
Sharmila Anandasabapathy ◽  
Dipen Maru ◽  
Rebecca Richards-Kortum
Keyword(s):  
High Resolution ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Low Cost ◽  
High Resolution Imaging ◽  
Resolution Imaging

Design and Validation of a Low-Cost Microscope for Diagnostics in the Developing World

2009 ◽  
Vol 17 (6) ◽  
pp. 16-19 ◽  
Author(s):  
B. Cline ◽  
R. Luo ◽  
K. Kuhlmann
Keyword(s):  
High Resolution ◽  
Infectious Diseases ◽  
Developing World ◽  
Low Cost ◽  
High Resolution Imaging ◽  
Microscope Examination ◽  
Resource Limited Settings ◽  
Resource Limited ◽  
Resolution Imaging

Many infectious diseases prevalent in the developing world, including malaria and tuberculosis, are difficult to diagnose on the basis of symptoms alone but can be accurately detected using microscope examination. Currently the expense, size, and fragility of optical microscopes impede their widespread use in resource-limited settings. Addressing these obstacles facing microscopy in the developing world is a pressing need; over 800,000 people, primarily children in Africa, die annually of malaria, and more than 1,500,000 people die annually of tuberculosis [1][2]. The aim of this study is to design and validate a microscope for use in the developing world that combines high-resolution imaging, extreme affordability, and long-term durability.

scholarly journals A low-cost microwell device for high-resolution imaging of neurite outgrowth in 3D

2018 ◽  
Vol 15 (3) ◽  
pp. 035001
Author(s):  
Yuan Ren ◽  
Michael J Mlodzianoski ◽  
Aih Cheun Lee ◽  
Fang Huang ◽  
Daniel M Suter
Keyword(s):  
High Resolution ◽  
Neurite Outgrowth ◽  
Low Cost ◽  
High Resolution Imaging ◽  
Resolution Imaging

scholarly journals Ultra-High Resolution Imaging Method for Distributed Small Satellite Spotlight MIMO-SAR Based on Sub-Aperture Image Fusion

Sensors ◽  
2021 ◽  
Vol 21 (5) ◽  
pp. 1609
Author(s):  
Fang Zhou ◽  
Jun Yang ◽  
Lu Jia ◽  
Xingming Yang ◽  
Mengdao Xing
Keyword(s):  
High Resolution ◽  
Low Cost ◽  
Multiple Input Multiple Output ◽  
Imaging Method ◽  
High Resolution Imaging ◽  
Small Satellite ◽  
Fusion Algorithm ◽  
Large Bandwidth ◽  
Input Multiple Output ◽  
Resolution Imaging

Small satellite synthetic aperture radar (SAR) has become a new development direction of spaceborne SAR due to its advantages of flexible launch, short development cycle, and low cost. However, there are fewer researches on distributed small satellite multiple input multiple output (MIMO) SAR. This paper proposes an ultra-high resolution imaging method for the distributed small satellite spotlight MIMO-SAR, which applies the sub-aperture division technique and the sub-aperture image coherent fusion algorithm to MIMO-SAR. After deblurring the sub-aperture signal, the large bandwidth signal is obtained by using an improved time domain bandwidth synthesis (TBS) method, and then the ultra-high resolution image is obtained by using a sub-aperture image coherent fusion algorithm. Simulation results validate the feasibility and effectiveness of the proposed approach.

scholarly journals Low-cost, high-resolution imaging for detecting cervical precancer in medically-underserved areas of Texas

2019 ◽  
Vol 154 (3) ◽  
pp. 558-564 ◽  
Author(s):  
Sonia G. Parra ◽  
Ana M. Rodriguez ◽  
Katelin D. Cherry ◽  
Richard A. Schwarz ◽  
Rose M. Gowen ◽  
...  
Keyword(s):  
High Resolution ◽  
Low Cost ◽  
Medically Underserved ◽  
High Resolution Imaging ◽  
Medically Underserved Areas ◽  
Resolution Imaging ◽  
Cervical Precancer

Alternative approaches to ultra-high resolution imaging

1991 ◽  
Vol 49 ◽  
pp. 650-651
Author(s):  
J.M. Cowley
Keyword(s):  
High Resolution ◽  
High Voltage ◽  
High Resolution Electron Microscopy ◽  
Crystal Defects ◽  
High Resolution Imaging ◽  
General Applicability ◽  
Resolution Electron ◽  
Radiation Resistant ◽  
Resolution Imaging ◽  
Alternative Approaches

By extrapolation of past experience, it would seem that the future of ultra-high resolution electron microscopy rests with the advances of electron optical engineering that are improving the instrumental stability of high voltage microscopes to achieve the theoretical resolutions of 1Å or better at 1MeV or higher energies. While these high voltage instruments will undoubtedly produce valuable results on chosen specimens, their general applicability has been questioned on the basis of the excessive radiation damage effects which may significantly modify the detailed structures of crystal defects within even the most radiation resistant materials in a period of a few seconds. Other considerations such as those of cost and convenience of use add to the inducement to consider seriously the possibilities for alternative approaches to the achievement of comparable resolutions.

Principle and practice of high-resolution imaging with a field-emission TEM

1992 ◽  
Vol 50 (1) ◽  
pp. 138-139
Author(s):  
Max T. Otten ◽  
Wim M.J. Coene
Keyword(s):  
High Resolution ◽  
Field Emission ◽  
Incidence Angle ◽  
Temporal Coherence ◽  
Energy Spread ◽  
High Resolution Imaging ◽  
Major Improvement ◽  
High Resolution Images ◽  
Resolution Imaging

High-resolution imaging with a LaB6 instrument is limited by the spatial and temporal coherence, with little contrast remaining beyond the point resolution. A Field Emission Gun (FEG) reduces the incidence angle by a factor 5 to 10 and the energy spread by 2 to 3. Since the incidence angle is the dominant limitation for LaB6 the FEG provides a major improvement in contrast transfer, reducing the information limit to roughly one half of the point resolution. The strong improvement, predicted from high-resolution theory, can be seen readily in diffractograms (Fig. 1) and high-resolution images (Fig. 2). Even if the information in the image is limited deliberately to the point resolution by using an objective aperture, the improved contrast transfer close to the point resolution (Fig. 1) is already worthwhile.

Imaging of ferroelectric domain walls by electron holography

1992 ◽  
Vol 50 (1) ◽  
pp. 246-247
Author(s):  
Xiao Zhang
Keyword(s):  
Magnetic Field ◽  
High Resolution ◽  
Domain Walls ◽  
Ferroelectric Domain ◽  
Object Wave ◽  
Electron Holography ◽  
High Resolution Imaging ◽  
Quantitative Measurements ◽  
Resolution Imaging ◽  
Electron Microscopes

Electron holography has recently been available to modern electron microscopy labs with the development of field emission electron microscopes. The unique advantage of recording both amplitude and phase of the object wave makes electron holography a effective tool to study electron optical phase objects. The visibility of the phase shifts of the object wave makes it possible to directly image the distributions of an electric or a magnetic field at high resolution. This work presents preliminary results of first high resolution imaging of ferroelectric domain walls by electron holography in BaTiO3 and quantitative measurements of electrostatic field distribution across domain walls.

The method of replication affects metal film granularity and resolution

1989 ◽  
Vol 47 ◽  
pp. 708-709
Author(s):  
George C. Ruben
Keyword(s):  
Electron Beam ◽  
High Resolution ◽  
Film Thickness ◽  
Single Molecule ◽  
Metal Film ◽  
Vertical Surface ◽  
High Resolution Imaging ◽  
Controllable Factors ◽  
Resolution Imaging

Single molecule resolution in electron beam sensitive, uncoated, noncrystalline materials has been impossible except in thin Pt-C replicas ≤ 150Å) which are resistant to the electron beam destruction. Previously the granularity of metal film replicas limited their resolution to ≥ 20Å. This paper demonstrates that Pt-C film granularity and resolution are a function of the method of replication and other controllable factors. Low angle 20° rotary , 45° unidirectional and vertical 9.7±1 Å Pt-C films deposited on mica under the same conditions were compared in Fig. 1. Vertical replication had a 5A granularity (Fig. 1c), the highest resolution (table), and coated the whole surface. 45° replication had a 9Å granulartiy (Fig. 1b), a slightly poorer resolution (table) and did not coat the whole surface. 20° rotary replication was unsuitable for high resolution imaging with 20-25Å granularity (Fig. 1a) and resolution 2-3 times poorer (table). Resolution is defined here as the greatest distance for which the metal coat on two opposing faces just grow together, that is, two times the apparent film thickness on a single vertical surface.

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