ID: 3524531 DIAGNOSTIC PERFORMANCE OF THE CRITERIA FOR RISK STRATIFICATION OF CHOLEDOCHOLITHIASIS OF THE 2019 GUIDELINES OF THE AMERICAN GASTROINTESTINAL ENDOSCOPY SOCIETY, IN A GENERAL HOSPITAL LOCATED IN THE SOUTH OF MEXICO CITY

2021 ◽  
Vol 93 (6) ◽  
pp. AB131
Author(s):  
Miguel A. Lopez y Lopez ◽  
Francisco Rafael Valencia Alvarez ◽  
Luis E. Cárdenas Lailson ◽  
Ignacio del Rio Suárez ◽  
Roberto Delano-Alonso ◽  
...  
PEDIATRICS ◽  
1968 ◽  
Vol 41 (3) ◽  
pp. 664-666
Author(s):  
Héctor Márquez-Monter ◽  
Alessandra Carnevale-López ◽  
Susana Kofman-Alfaro

A survey of sex chromatin was carried out in 3,000 newborn children at the General Hospital of Mexico City; 1,484 were males and 1,516 were females. In the male group 4 infants (0.26%) had positive chromatin and were considered to have a possible XXY or XXYY constitution. In the female group 3 infants (0.19%) did not show sex chromatin and were possible carriers of an XO complement. No correlation was found between the maternal age and number of pregnancies and the discrepant children. A comparison was made between the results obtained in this study and similar studies carried out in other countries. Fourteen instances of congenital abnormalities were found in this study; Down's syndrome was the most frequent (1/750-0.13%).


2021 ◽  
Vol 16 (2) ◽  
Author(s):  
Rafael Gutiérrez‑García ◽  
Juan C. De La Cerda‑Angeles ◽  
Ariana Cabrera‑Licona ◽  
Ivan Delgado‑Enciso ◽  
Nicolas Mervitch‑Sigal ◽  
...  

2021 ◽  
Vol 11 ◽  
Author(s):  
Xuehua Xi ◽  
Ying Wang ◽  
Luying Gao ◽  
Yuxin Jiang ◽  
Zhiyong Liang ◽  
...  

BackgroundThe incidence and mortality of thyroid cancer, including thyroid nodules > 4 cm, have been increasing in recent years. The current evaluation methods are based mostly on studies of patients with thyroid nodules < 4 cm. The aim of the current study was to establish a risk stratification model to predict risk of malignancy in thyroid nodules > 4 cm.MethodsA total of 279 thyroid nodules > 4 cm in 267 patients were retrospectively analyzed. Nodules were randomly assigned to a training dataset (n = 140) and a validation dataset (n = 139). Multivariable logistic regression analysis was applied to establish a nomogram. The risk stratification of thyroid nodules > 4 cm was established according to the nomogram. The diagnostic performance of the model was evaluated and compared with the American College Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS), Kwak TI-RADS and 2015 ATA guidelines using the area under the receiver operating characteristic curve (AUC).ResultsThe analysis included 279 nodules (267 patients, 50.6 ± 13.2 years): 229 were benign and 50 were malignant. Multivariate regression revealed microcalcification, solid mass, ill-defined border and hypoechogenicity as independent risk factors. Based on the four factors, a risk stratified clinical model was developed for evaluating nodules > 4 cm, which includes three categories: high risk (risk value = 0.8-0.9, with more than 3 factors), intermediate risk (risk value = 0.3-0.7, with 2 factors or microcalcification) and low risk (risk value = 0.1-0.2, with 1 factor except microcalcification). In the validation dataset, the malignancy rate of thyroid nodules > 4 cm that were classified as high risk was 88.9%; as intermediate risk, 35.7%; and as low risk, 6.9%. The new model showed greater AUC than ACR TI-RADS (0.897 vs. 0.855, p = 0.040), but similar sensitivity (61.9% vs. 57.1%, p = 0.480) and specificity (91.5% vs. 93.2%, p = 0.680).ConclusionMicrocalcification, solid mass, ill-defined border and hypoechogenicity on ultrasound may be signs of malignancy in thyroid nodules > 4 cm. A risk stratification model for nodules > 4 cm may show better diagnostic performance than ACR TI-RADS, which may lead to better preoperative decision-making.


2014 ◽  
Vol 05 (13) ◽  
pp. 1290-1298 ◽  
Author(s):  
Rey Gutiérrez Tolentino ◽  
Salvador Vegay León ◽  
Beatriz Schettino Bermúdez ◽  
Guadalupe Prado Flores ◽  
María de Lourdes Ramírez Vega ◽  
...  

Author(s):  
Sue Brownill ◽  
Oscar Natividad Puig

This chapter draws on debates about the need for theory to ‘see from the South’ (Watson, 2009) to critically reflect on the increasingly global nature of co-creation both as a focus for research and for initiatives from governments around the world. It explores whether current understandings of co-creation narratives, which have tended to come from the Global North, can adequately characterise and understand the experience from the South, and the resulting need to decolonise knowledge and conduct research into the diverse ways in which co-creation can be constituted. It goes on to illustrate these debates by exploring the differing contexts for co-creation created by state-civil society relations in the project’s participating countries. These show that, while distinct contrasts emerge, it is important to move beyond dichotomies of north and south to explore the spaces of participation and resistance that are created within different contexts and how these are navigated by projects and communities engaged in co-creation. The chapter draws on material from interviews with local stakeholders and academics involved in the Co-Creation project and project conferences in Rio, Mexico City and Berlin.


2020 ◽  
Vol 9 (1) ◽  
pp. 236 ◽  
Author(s):  
Simone Schenke ◽  
Rigobert Klett ◽  
Philipp Seifert ◽  
Michael C. Kreissl ◽  
Rainer Görges ◽  
...  

Due to the widespread use of ultrasound, small thyroid nodules (TNs) ≤ 10 mm are common findings. Standardized approaches for the risk stratification of TNs with Thyroid Imaging Reporting and Data Systems (TIRADS) were evaluated for the clinical routine. With TIRADS, the risk of malignancy in TNs is calculated by scoring the number or combination of suspicious ultrasound features, leading to recommendations for further diagnostic steps. However, there are only scarce data on the performance of TIRADS for small TNs. The aim was to compare three different TIRADS for risk stratification of small TNs in routine clinical practice. We conducted a retrospective cohort analysis of TNs ≤ 10 mm and their available histology. Nodules were classified according to three different TIRADS. In the study, 140 patients (n = 113 female) with 145 thyroid nodules (n = 76 malignant) were included. Most of the malignant nodules were papillary carcinoma (97%), and the remaining 3% were medullary carcinoma. For all tested TIRADS, the prevalence of malignancy rose with increasing category levels. The highest negative predictive value was found for ACR TI-RADS and the highest positive predictive value for Kwak-TIRADS. All tested variants of TIRADS showed comparable diagnostic performance for the risk stratification of small TNs. TIRADS seems to be a promising tool to reliably assess the risk of malignancy of small TNs.


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