Normative values of the DASH questionnaire in healthy individuals over 50 years of age

Author(s):  
A. Gkotsi ◽  
C. Bourdon ◽  
C. Robert ◽  
F. Schuind
Author(s):  
Edoardo Nicolò Aiello ◽  
Chiara Gramegna ◽  
Antonella Esposito ◽  
Valentina Gazzaniga ◽  
Stefano Zago ◽  
...  

Abstract Background The availability of fine-grained, culture-specific psychometric outcomes can favor the interpretation of scores of the Montreal Cognitive Assessment (MoCA), the most frequently used instrument to screen for mild cognitive dysfunctions in both instrumental and non-instrumental domains. This study thus aimed at providing: (i) updated, region-specific norms for the Italian MoCA, by also (ii) comparing them to pre-existing ones with higher geographical coverage; (iii) information on sensitivity and discriminative capability at the item level. Methods Five hundred and seventy nine healthy individuals from Northern Italy (208 males, 371 females; age: 63.4 ± 15, 21–96; education: 11.3 ± 4.6, 1–25) were administered the MoCA. Item Response Theory (IRT) was adopted to assess item difficulty and discrimination. Normative values were derived by means of the Equivalent Scores (ESs) method, applied to the MoCA and its sub-scales. Average ESs were also computed. Agreement with previous ESs classification was assessed via Cohen’s k. Results Age and education significantly predicted all MoCA measures except for Orientation, which was related to age only. No sex differences were detected when tested along with age and education. Substantial disagreements with previous ESs classifications were detected. Several items proved to be scarcely sensitive, especially the place item from Orientation and the letter detection task. Memory items showed high discriminative capability, along with certain items assessing executive functions and orientation. Discussion Item-level information herewith provided for the Italian MoCA can help interpret its scores by Italian practitioners. Italian practitioners should consider an adaptive use of region-specific norms for the MoCA.


2019 ◽  
pp. 269-284 ◽  
Author(s):  
Nicholas Murry ◽  
Karla Kubitz ◽  
Claire-Marie Roberts ◽  
Melissa Hunfalvay ◽  
Takumi Bolte ◽  
...  

Objective The purpose of this study was to examine the reliability of oculomotor metrics in healthy individuals, to determine the normative values through cluster analysis, and to compare oculomotor metrics by age groups in a suite of digitized eye tracking tests. Design Experimental cross sectional Participants A large sample of 2993 participants completed RightEye tests. Results These tests demonstrated acceptable or higher reliability on 85% of the eye movement metrics and the clustering analysis distinguished 5 distinct age groups. Furthermore, group differences were found between age clusters. Conclusions Overall, the findings represent the reliability of a computerized oculomotor measure and the importance to consider individual and group characteristics for clinical applications as well as applied settings.


2019 ◽  
Vol 97 (2) ◽  
pp. 107-111 ◽  
Author(s):  
Jacquie Baker ◽  
Kurt Kimpinski

In evaluating autonomic dysfunction, the autonomic reflex screen (ARS) is an established set of standardized tests to evaluate the presence and severity of autonomic dysfunction. Our laboratory previously reported normative data on 121 healthy individuals; however, the sample size in older individuals was reduced compared with other age groups. Therefore, the objective of the current study was to provide updated normative values representative of young, middle-aged, and older individuals from Southwestern Ontario. Two hundred and fifty-two healthy individuals completed quantitative sudomotor axon reflex testing, heart rate responses to deep breathing (HRDB), and Valsalva maneuver using standard protocols of the ARS. All 4 sweat sites demonstrated a significant effect of sex (p < 0.001). In addition, the proximal leg, distal leg, and foot were all significantly affected by age (p < 0.001). Cardiovagal parameters, measured via HRDB and Valsalva ratio revealed a significant regression with age (p < 0.001). These results show similar trends with previously reported normative data sets. All normative data as a function of age and sex, where appropriate, are expressed as percentiles (2.5th, 5th, 95th, 97.5th). The current study provides updated normative data describing autonomic functioning in healthy individuals obtained from the sudomotor and cardiovagal components of the ARS.


2018 ◽  
Vol 61 ◽  
pp. e435
Author(s):  
Y. Palad ◽  
A. Leaver ◽  
M. McKay ◽  
J. Baldwin ◽  
F.R. Lunar ◽  
...  

2021 ◽  
Vol 20 (5) ◽  
pp. 65-72
Author(s):  
Irina V. Borodulina ◽  
Irina V. Borodulina ◽  
Ekaterina I. Chesnikova

The use of instrumental diagnosis methods is a way to form an individual strategy of rehabilitation treatment and effectiveness monitoring. However, there is a lack of methods for objective assessment of the muscle groups’ functional state in both patients with dorsopathy and healthy individuals, as well as incorrect use of existing diagnostic tools due to the lack of the regulatory framework. The subjects had no complaints on low back pain, and there was no history of pain episodes associated with spinal pathology. All the volunteers were comparable in height and weight before being included in the study. The study was conducted in accordance with the terms of the Helsinki Declaration, all subjects signed an informed consent before the start of diagnostic activities. Aim. To determine the normative values of the strength of the flexor muscle group (FM) and extensor muscles (EM) of the lumbosacral spine and to establish the ratio of the obtained results to the automatic hardware norm. Material and methods. The present clinical study included 22 healthy volunteers aged 23 to 61 years (the average age was 38.4±12.8 years), including 14 women (63.6%) and 8 men (36.4%). Results and discussion. The results obtained demonstrate that the real normative indicators for MS and MR in healthy individuals can vary in the range from the hardware norm value calculated automatically by the device to a value of 20% lower. Exceeding this parameter is not a pathological deviation. When assessing the muscle strength, a decrease in this indicator is of physiological and clinical significance, since it reflects the dysfunction of this area and is a predictor of the pain syndrome chronicity. Conclusion. The standard values findings allow us to assess correctly the initial clinical condition and use this instrumental method with biofeedback for patients with degenerative spinal lesion and non-specific pain in the lumbosacral region and patients who have undergone spinal surgery to develop individual rehabilitation programs. As a further prospect for the use of diagnostic systems with biofeedback, it is suggested that the examination plan should include the determination of the ratio of the FM strength to the EM strength, as well as the strength of the muscles involved in the lateral slopes of the trunk.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Uttanoor Sreedevi ◽  
Gopala Krishna Alaparthi ◽  
Shyam krishnan ◽  
Kalyana Chakravarthy Bairapareddy ◽  
R. Anand ◽  
...  

Background. Due to increase in the life expectancy and changes related to aging, it is important to assess ADL (activities of daily living) in older adults. However, there is no standardized protocol available to assess ADLs. Considering the limitations of the available tools, a new protocol named Londrina ADL protocol was developed for which normative values are unavailable in different ethnic groups. Objective. To develop the normative value and reference equation for the Londrina ADL protocol on the basis of anthropometric and demographic variables in healthy individuals in the age group of 40–60 years among the Indian population. Methods. This cross-sectional study was conducted with 282 healthy individuals of both the genders between the age group of 40 and 60 and they were divided into 2 groups: 40–49 and 50–60. Each subject was made to perform the Londrina ADL protocol twice with a 30 min interval between the two protocols. The protocol is composed of 5 activities and the best out of the 2 performances were recorded. Results. The mean time taken among 40–49 years by females is 3.50 ± 0.50 min and by males is 3.73 ± 0.43 min. The mean time taken among 50–60 years by females is 4.25 ± 0.20 min and by males is 4.36 ± 0.18 min. The reference equation to predict reference values for the Londrina ADL protocol was as follows: equation (1): Londrina ADL predicted = 1.205 + (0.054 × age (years)) + (0.001 × height (cm)); equation (2): Londrina ADL predicted = 1.374 + (0.054 × age (years)) + (−0.003 × BMI). Conclusion. The reference equation for the time to complete the Londrina ADL protocol was based on age and BMI as independent variables and can be useful for predicting the performance of healthy individuals.


Author(s):  
Michaela Plath ◽  
Matthias Sand ◽  
Philippe A. Federspil ◽  
Peter K. Plinkert ◽  
Ingo Baumann ◽  
...  

Abstract Purpose The study aimed to determine normative values for the Tonsillectomy Outcome Inventory 14 (TOI-14) in a healthy middle-European cohort. We also compared these generated values with TOI-14 scores from a patient population with recurrent tonsillitis (RT) and explored the factorial structure of the TOI-14. Methods We systematically studied the responses of healthy individuals (reference cohort) and patients with RT (clinical cohort) to the TOI-14 survey. The reference cohort contained 1000 participants, who were recruited using the Respondi panel for market and social science research. This subsample was quoted to the population distribution of the German Microcensus and selected from a non-probability panel. Tonsillitis patients were assessed before and 6 and 12 months after tonsillectomy. Data were analysed using principal component and exploratory factor analyses. Results The PCA revealed three TOI-14 domains (physiological, psychological and socio-economic), which explained 73% of the total variance. The reference cohort perceived a good quality of life (QOL) with a TOI-14 total score of 11.8 (physiological: 8.0, psychological: 5.8, and socio-economic subscale score: 13.9). TOI-14 scores were higher in the patient cohort, indicating that the TOI-14 discriminates between patients with RT and healthy individuals with no RT. Age and female gender significantly influenced the total TOI-14 score, especially in the psychological (age) and socio-economic (gender) subscales. Conclusion We have developed a set of normative values that, together with the TOI-14, can determine the disease burden indicating tonsillectomy.


2015 ◽  
Vol 64 (2) ◽  
pp. 137-140
Author(s):  
V. Umamaheswara Reddy ◽  
Kishor V. Hegde ◽  
Amit Agrawal ◽  
Rama Mohan Pathapati ◽  
Mithilesh Arumulla

2018 ◽  
Vol 76 (3) ◽  
pp. 163-169 ◽  
Author(s):  
Alfredo Damasceno ◽  
Juliana Machado Santiago dos Santos Amaral ◽  
Amilton Antunes Barreira ◽  
Jefferson Becker ◽  
Dagoberto Callegaro ◽  
...  

ABSTRACT Objective Cognitive dysfunction is common in multiple sclerosis. The Brief Repeatable Battery of Neuropsychological Tests (BRB–N) was developed to assess cognitive functions most–frequently impaired in multiple sclerosis. However, normative values are lacking in Brazil. Therefore, we aimed to provide continuous and discrete normative values for the BRB–N in a Brazilian population sample. Methods We recruited 285 healthy individuals from the community at 10 Brazilian sites and applied the BRB–N version A in 237 participants and version B in 48 participants. Continuous norms were calculated with multiple–regression analysis. Results Mean raw scores and the 5th percentile for each neuropsychological measure are provided, stratified by age and educational level. Healthy participants' raw scores were converted to scaled scores, which were regressed on age, sex and education, yielding equations that can be used to calculate predicted scores. Conclusion Our normative data allow a more widespread use of the BRB–N in clinical practice and research.


Author(s):  
B. J. Panessa-Warren ◽  
J. B. Warren ◽  
H. W. Kraner

Our previous studies have demonstrated that abnormally high amounts of calcium (Ca) and zinc (Zn) can be accumulated in human retina-choroid under pathological conditions and that barium (Ba), which was not detected in the eyes of healthy individuals, is deposited in the retina pigment epithelium (RPE), and to a lesser extent in the sensory retina and iris. In an attempt to understand how these cations can be accumulated in the vertebrate eye, a morphological and microanalytical study of the uptake and loss of specific cations (K, Ca,Ba,Zn) was undertaken with incubated Rana catesbiana isolated retina and RPE preparations. Large frogs (650-800 gms) were dark adapted, guillotined and their eyes enucleated in deep ruby light. The eyes were hemisected behind the ora serrata and the anterior portion of the eye removed. The eyecup was bisected along the plane of the optic disc and the two segments of retina peeled away from the RPE and incubated.


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