Antimicrobial resistance of bacterial isolates from respiratory care wards in Taiwan: a horizontal surveillance study comparison of the characteristics of nosocomial infection and antimicrobial-resistant bacteria in adult Intensive Care Units and two respiratory care facilities for mechanically ventilated patients at a tertiary care centre in Taiwan

2011 ◽  
Vol 37 (1) ◽  
pp. 10-15 ◽  
Author(s):  
Keh-Sen Liu ◽  
Yao-Tung Wang ◽  
Yi-Chyi Lai ◽  
Su-Fang Yu ◽  
Shu-Ju Huang ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Resistant Bacteria ◽  
Respiratory Care ◽  
Care Centre ◽  
Bacterial Isolates ◽  
Tertiary Care Centre ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Care Facilities ◽  
Ventilated Patients

Critical Care Nurses’ Knowledge of Sedation and Its Management in Mechanically Ventilated Patients at a Tertiary Care Hospital in Pakistan

2020 ◽  
Vol 14 (1) ◽  
pp. 7-18
Author(s):  
Samuel Masih ◽  
Khairunnisa Aziz Dhamani ◽  
Sadia Farhan Khan
Keyword(s):  
Critical Care ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Critical Care Nurses ◽  
Good Knowledge ◽  
Care Hospital ◽  
Poor Knowledge ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Ventilated Patients

BackgroundSedation assessment and management is an essential part of critical care nursing. The patients are at significant risks of undersedation and oversedation. Critical care nurses must possess sufficient knowledge about sedation assessment and its management.AimThis study aimed to determine critical care nurses’ knowledge of sedation and its management in mechanically ventilated patients in Pakistan.MethodologyA cross-sectional descriptive study was conducted. The participants were recruited from three critical care units of a tertiary care hospital using a consecutive sampling technique. Data were collected using a self-administered questionnaire.FindingsIn total, 91 critical care nurses participated in this study. Most of them had less than 2 years of experience as registered nurses and as intensive care unit nurses. The majority of them had insufficient knowledge (poor knowledge 18.7% and fair knowledge 63.7%), whereas only 17.6% had good knowledge of sedation and its management. The average correct response rate for general knowledge of sedation management practices was 71.3%. Almost half of the participants (51.6%) had poor knowledge of assessing undersedation and oversedation. Overall, 67% of nurses had good knowledge of managing sedative drugs.ConclusionThe majority of critical nurses lacked sufficient knowledge related to sedation and its management in mechanically ventilated patients. This poses risks to patients’ safety and quality of care.

scholarly journals Dynamics of SARS-CoV2 Infection and Multi-Drug Resistant Bacteria Superinfection in Patients With Assisted Mechanical Ventilation

2021 ◽  
Vol 11 ◽  
Author(s):  
Annarita Mazzariol ◽  
Anna Benini ◽  
Ilaria Unali ◽  
Riccardo Nocini ◽  
Marcello Smania ◽  
...  
Keyword(s):  
Fungal Infections ◽  
Fungal Growth ◽  
Carbapenem Resistance ◽  
Resistant Bacteria ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Assisted Mechanical Ventilation ◽  
Bacteria And Fungi ◽  
A Prospective Study ◽  
Ventilated Patients

ObjectiveTo investigate the presence of bacteria and fungi in bronchial aspirate (BA) samples from 43 mechanically ventilated patients with severe COVID-19 disease.MethodsDetection of SARS-CoV-2 was performed using Allplex 2019-nCoV assay kits. Isolation and characterisation of bacteria and fungi were carried out in BA specimens treated with 1X dithiothreitol 1% for 30 min at room temperature, using standard culture procedures.ResultsBacterial and/or fungal superinfection was detected in 25 out of 43 mechanically ventilated patients, generally after 7 days of hospitalisation in an intensive care unit (ICU). Microbial colonisation (colony forming units (CFU) <1000 colonies/ml) in BA samples was observed in 11 out of 43 patients, whereas only 7 patients did not show any signs of bacterial or fungal growth. Pseudomonas aeruginosa was identified in 17 patients. Interestingly, 11 out of these 17 isolates also showed carbapenem resistance. The molecular analysis demonstrated that resistance to carbapenems was primarily related to OprD mutation or deletion. Klebsiella pneumoniae was the second most isolated pathogen found in 13 samples, of which 8 were carbapenemase-producer strains.ConclusionThese data demonstrate the detection of bacterial superinfection and antimicrobial resistance in severe SARS-CoV-2-infected patients and suggest that bacteria may play an important role in COVID-19 evolution. A prospective study is needed to verify the incidence of bacterial and fungal infections and their influence on the health outcomes of COVID-19 patients.

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