Analysis of hydration water around human serum albumin using near-infrared spectroscopy

2019 ◽  
Vol 138 ◽  
pp. 927-932 ◽  
Author(s):  
Qin Dong ◽  
Chen Yu ◽  
Lian Li ◽  
Lei Nie ◽  
Hui Zhang ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Hydration Water

Highly precise characterization of the hydration state upon thermal denaturation of human serum albumin using a 65 GHz dielectric sensor

2020 ◽  
Vol 22 (35) ◽  
pp. 19468-19479 ◽  
Author(s):  
Keiichiro Shiraga ◽  
Mako Urabe ◽  
Takeshi Matsui ◽  
Shojiro Kikuchi ◽  
Yuichi Ogawa
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Thermal Denaturation ◽  
Hydration Water ◽  
Biological Functions ◽  
Dielectric Sensor ◽  
Hydration State ◽  
Precise Characterization

The biological functions of proteins depend on harmonization with hydration water surrounding them.

Detection of the Communication Site by Indocyanine Green Adsorbed to Human Serum Albumin Fluorescence During Surgery for a Pleuroperitoneal Communication

2021 ◽  
Author(s):  
Daisuke Kimura ◽  
Ikuo Fukuda ◽  
Takeshi Fujita ◽  
Reiichi Murakami ◽  
Norio Nakamura ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Indocyanine Green ◽  
Human Serum ◽  
Near Infrared ◽  
Thoracoscopic Surgery ◽  
Good Method ◽  
Pleuroperitoneal Communication ◽  
Fluorescence Images ◽  
One Year

Abstract A pleuroperitoneal communication is a serious complication for patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Video-assisted thoracoscopic surgery is performed using indocyanine green adsorbed to human serum albumin fluorescence to identify the communication because human serum albumin reinforces fluorescence images. A patient diagnosed with a pleuroperitoneal communication was referred to our department and underwent surgery. To detect the communication, a dialysate mixture that contained indocyanine green and human serum albumin was injected from the CAPD catheter. Real-time fluorescence images were able to clearly show a bleb-like lesion with a near-infrared spectroscopy camera, and the site was repaired. The patient had no recurrence at one-year follow-up. This method might be good method for pleuroperitoneal communication surgery.

Human serum albumin (HSA) coated liposomal indocyanine green for in vivo tumor imaging

RSC Advances ◽  
2016 ◽  
Vol 6 (18) ◽  
pp. 15220-15225 ◽  
Author(s):  
Siqin Chen ◽  
Gongjie Yu ◽  
Bo Zhang ◽  
Yinsong Wang ◽  
Ning Zhang ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Indocyanine Green ◽  
Human Serum ◽  
Near Infrared ◽  
Tumor Imaging ◽  
Fluorescent Nanoprobe

In this study, a near-infrared (NIR) fluorescent nanoprobe based on indocyanine green (ICG) was synthesized.

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