scholarly journals Persistent candidemia despite appropriate fungal therapy: First case of Candida auris from the United Arab Emirates

2018 ◽  
Vol 70 ◽  
pp. 36-37 ◽  
Author(s):  
Adnan Alatoom ◽  
Mohammad Sartawi ◽  
Karen Lawlor ◽  
Laila AbdelWareth ◽  
Jens Thomsen ◽  
...  
Keyword(s):  
United Arab Emirates ◽  
Candida Auris ◽  
First Case ◽  
Persistent Candidemia

Policy Review: Dubai Health Authority’s COVID-19 Rapid Response

2020 ◽  
Vol 5 (Special) ◽  
Keyword(s):  
United Arab Emirates ◽  
Well Being ◽  
Healthcare Services ◽  
Rapid Response ◽  
Policy Implications ◽  
World Health ◽  
Healthcare Sector ◽  
Services Delivery ◽  
First Case ◽  
The World

Dubai Health Authority (DHA) is the entity regulating the healthcare sector in the Emirate of Dubai, ensuring high quality and safe healthcare services delivery to the population. The World Health Organization (WHO) declared COVID-19 a pandemic on the 11th of March 2020, indicating to the world that further infection spread is very likely, and alerting countries that they should be ready for possible widespread community transmission. The first case of COVID-19 in the United Arab Emirates was confirmed on 29th of January 2020; since then, the number of cases has continued to grow exponentially. As of 8th of July 2020 (end of the day), 53,045 cases of coronavirus have been confirmed with a death toll of 327 cases. The UAE has conducted over 3,720,000 COVID-19 tests among UAE citizens and residents over the past four months, in line with the government’s plans to strengthen virus screening to contain the spread of COVID-19. There were vital UAE policies, laws, regulations, and decrees that have been announced for immediate implementation to limit the spread of COVID- 19, to prevent panic and to ensure the overall food, nutrition, and well-being are provided. The UAE is amongst the World’s Top 10 for COVID-19 Treatment Efficiency and in the World’s Top 20 for the implementation of COVID-19 Safety measures. The UAE’s mission is to work towards resuming life after COVID-19 and enter into the recovery phases. This policy research paper will discuss the Dubai Health Authority’s rapid response initiatives towards combating the control and spread of COVID-19 and future policy implications and recommendations. The underlying factors and policy options will be discussed in terms of governance, finance, and delivery.

scholarly journals Emergence of Candida auris in Brazil in a COVID-19 Intensive Care Unit

2021 ◽  
Vol 7 (3) ◽  
pp. 220
Author(s):  
João N. de Almeida ◽  
Elaine C. Francisco ◽  
Ferry Hagen ◽  
Igor Brandão ◽  
Felicidade M. Pereira ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Antifungal Susceptibility ◽  
Candida Auris ◽  
Minimal Inhibitory Concentrations ◽  
First Case ◽  
Asian Clade ◽  
Travel Restrictions ◽  
Clade C ◽  
The City

In December 2020, Candida auris emerged in Brazil in the city of Salvador. The first two C. auris colonized patients were in the same COVID-19 intensive care unit. Antifungal susceptibility testing showed low minimal inhibitory concentrations of 1 µg/mL, 2 µg/mL, 0.03 µg/L, and 0.06 µg/mL for amphotericin B, fluconazole, voriconazole, and anidulafungin, respectively. Microsatellite typing revealed that the strains are clonal and belong to the South Asian clade C. auris. The travel restrictions during the COVID-19 pandemic and the absence of travel history among the colonized patients lead to the hypothesis that this species was introduced several months before the recognition of the first case and/or emerged locally in the coastline Salvador area.

scholarly journals Progeroid Syndrome of De Barsy With Hypocalcemic Seizures

2012 ◽  
Vol 32 (2) ◽  
pp. 175-177
Author(s):  
J Cheriathu ◽  
IE D'souza ◽  
LJ John ◽  
R El Bahtimi
Keyword(s):  
Clinical Features ◽  
United Arab Emirates ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Cutis Laxa ◽  
Cerebral Malformation ◽  
Malformation Syndrome ◽  
Intrauterine Growth ◽  
Corneal Clouding ◽  
First Case

De Barsy et al first reported a rare cutaneo-oculo-cerebral malformation-syndrome now commonly referred as ‘progerioid syndrome of de Barsy’. It is the constellation of progeria-like appearance, cutis laxa, intrauterine growth retardation, corneal clouding and hypotonia. We report a case of Debarsy syndrome in a neonate presented at birth with typical clinical features with hypocalcemic seizures. There are no previous reports among Afghani origin and also first case reported from United Arab Emirates, there have been no reported cases of hypocalcemic seizures. J Nepal Paediatr Soc 2012;32(2):175-177 doi: http://dx.doi.org/10.3126/jnps.v32i2.5993

scholarly journals First Case of COVID-19 Positive Candida auris Fungemia in Turkey

2021 ◽  
Vol 55 (4) ◽  
pp. 648-655
Author(s):  
Yasemin Bölükbaşı ◽  
Gonca Erköse Genç ◽  
Günseli Orhun ◽  
Mert Ahmet Kuşkucu ◽  
Atahan Çağatay ◽  
...  
Keyword(s):  
Candida Auris ◽  
First Case

scholarly journals 680. Month Long Fungemia due to Candida auris Endocarditis

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S443-S443
Author(s):  
Haseeba khan ◽  
Christy Varughese ◽  
Hemil Gonzalez
Keyword(s):  
Fungal Infections ◽  
Antifungal Susceptibility ◽  
Acute Care Hospital ◽  
Sigmoid Resection ◽  
Blood Cultures ◽  
Multi Drug Resistance ◽  
Care Hospital ◽  
Candida Auris ◽  
Candida Spp ◽  
First Case

Abstract Background Candida auris (C. auris) is a multidrug resistant Candida species, reported to cause persistent fungemia along with a multitude of invasive fungal infections. We report the first case of C. auris fungemia due to endocarditis. Methods 61 year old man with a history of diverticulitis that required sigmoid resection and was complicated by abdominal abscesses due to multi drug resistant organisms warranting heavy antibiosis. Prolonged hospitalisation for that surgery was followed by a stay at a long term acute care hospital. He was readmitted at an outside hospital with sepsis where blood cultures grew C.auris. Upon evaluation, was found to have aortic valve endocarditis. Per patient’s preference, surgery was initially deferred. Despite escalation of therapy with a combination of antifungals, he remained fungemic for five weeks with repeat blood cultures showing changing antifungal susceptibility patterns. Patient eventually underwent surgical intervention at our facility, with valve cultures being positive for C.auris. After the surgery he was treated with 6 weeks of intravenous combination antifungal therapy. Results C.auris’s pathogenicity stems from multiple mechanisms with multi drug resistance being most pertinent. What adds to the complexity of the management is the absence of C.auris specific minimum inhibitory concentration breakpoints. Therefore treatment is based on Center for Disease Control’s (CDC) proposed breakpoints that have been extrapolated from other Candida spp. It is further complicated by lack of C.auris specific data showing essential agreement among different commercially available antifungal susceptibility testing (AFST). Heteroresistance of the microbial population is an issue that must be considered in such protracted fungemia. Conclusion Invasive infections due to Candida auris presents as a diagnostic and therapeutic challenge to clinicians. Disclosures All Authors: No reported disclosures

First case of Candida auris isolated from the bloodstream of a Mexican patient with serious gastrointestinal complications from severe endometriosis

Infection ◽  
2020 ◽  
Author(s):  
J. Jacobo Ayala-Gaytán ◽  
Alexandra M. Montoya ◽  
Michel F. Martínez-Resendez ◽  
Claudia E. Guajardo-Lara ◽  
Rogelio de J. Treviño-Rangel ◽  
...  
Keyword(s):  
Candida Auris ◽  
Gastrointestinal Complications ◽  
First Case ◽  
Mexican Patient

scholarly journals Acute Thrombocytopenia, Leucopenia, and Multiorgan Dysfunction: The First Case of SFTS Bunyavirus outside China?

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Srdjan Denic ◽  
Joumana Janbeih ◽  
Suresh Nair ◽  
Walter Conca ◽  
Waheed Uz Zaman Tariq ◽  
...  
Keyword(s):  
Virus Infection ◽  
United Arab Emirates ◽  
North Korea ◽  
Disease Onset ◽  
Clinical Manifestations ◽  
Central China ◽  
New Disease ◽  
Multiorgan Dysfunction ◽  
First Case

We report a 57-year-old man with acute thrombocytopenia, leucopenia, and multiorgan dysfunction. Patient was from North Korea and was temporarily working in Dubai, United Arab Emirates, when he fell ill in March 2009. At the same time and unknown to us, many patients with similar clinical manifestations were admitted to hospitals in China. The Chinese cases—identified between March and July 2009—were recently reported to have been infected with a tick-born strain of bunyavirus, a new disease. The virus infection was documented in patients from central China and the region that shares the border with North Korea. The clinical manifestations, the time of disease onset, and geographical link of the patient with the region in which the disease is endemic suggest that the patient had SFTS bunyavirus infection.

scholarly journals The vaccination against COVID-19 in Morocco: a success story in progress

2021 ◽  
Keyword(s):  
United States ◽  
South Africa ◽  
Developing Countries ◽  
United Arab Emirates ◽  
The United States ◽  
Success Story ◽  
The United Kingdom ◽  
First Case ◽  
The World ◽  
Novel Coronavirus

Coronavirus disease 2019 is a respiratory sickness that may spread between persons. It is caused by a novel coronavirus that produces an outbreak in Wuhan, China and spread all over the world to become a pandemic. From the appearance of the first case of the new coronavirus in Morocco, Moroccan authorities has spared no effort to promote the health of Moroccans, ahead of that of the country’s economy. On 22 January 2021, 2 million doses, of AstraZeneca COVID-19 vaccine were delivered to Morocco, with a view to vaccinating 1 million Moroccans in a first phase. On 28 January, the campaign started and the King of Morocco was the 1st Moroccan to be vaccinated against the coronavirus. On 27 February 2021, Morocco has received 1 million doses from the Chinese laboratory Sinopharm and 6 million doses of the AstraZeneca vaccine allowing Morocco to vaccinate several audiences and the general public over the age of 60, and the most vulnerable. Thereafter, the COVID-19 vaccine doses administered per 100 people in 31 March 2021 were 115.89 in Israel, 84.01 in the United Arab Emirates, 52.53 in the United Kingdom, 44.93 in the United States, 45.04 in Bahrain, 21.66 in Morocco, 16.44 in Germany, 8.32 in China, 4.72 in India, and 0.44 in South Africa. Also, the population fully vaccinated against COVID-19 in 01 April 2021 were 55.51% in Israel, 22.12% in the United Arab Emirates, 20.08% in Chile, 16.77% in USA, 15.25% in Serbia, 15.14%in Bahrain, 10.21% in Morocco, 8.94% in Hungary, 8.23% in Turkey, 7.29% in UK, 3.07% in Russia, 2.39% in Brazil, 1.70% in Uruguay, 0.70% in India, and 0.45% in South Africa. This allows Morocco to figure in the top 10 countries fully vaccinated against COVID-19 despite the lack of resources and belonging to developing countries. Finally, our study gives an example to other countries to benefit from the Moroccan experience. Nevertheless, vaccination is only one element of a comprehensive COVID-19 strategy, it must be accompanied by measures to reduce circulating infection and keep them low.

scholarly journals Candida auris emergence in the Himalayan foothills: First case report from Uttarakhand, India

2020 ◽  
Author(s):  
Suneeta Meena ◽  
Ranjana Rohilla ◽  
Neelam Kaistha ◽  
Arpana Singh ◽  
Pratima Gupta
Keyword(s):  
Case Report ◽  
Tertiary Care ◽  
Multidrug Resistant ◽  
Whipple Procedure ◽  
Care Hospital ◽  
Candida Auris ◽  
Flight Mass Spectrometry ◽  
First Case ◽  
The Matrix ◽  
Head Of The Pancreas

Background and Purpose: Candida auris is a rapidly emerging fungus, which is considered globally a cause of concern for public health. This report describes the first case of C. auris fungemia from a tertiary care hospital in the hilly state of Uttarakhand in India. Case report: The patient was a 37-year-old female who underwent a Whipple procedure for the carcinoma of the head of the pancreas. She developed fever 12 days after the operation while recovering from surgery in the hospital. Blood culture yielded C. auris which was identified by the matrix-assisted laser desorption/ionization-time of flight mass spectrometry (Bruker Daltonics, Germany). The patient was successfully treated with caspofungin. Conclusion: In conclusion, C. auris is potentially multidrug resistant, resulting in nosocomial outbreaks and sporadic infections which can be potentially prevented when identified early by implementing contact precautionsBackground and Purpose: Candida auris is a rapidly emerging fungus, which is considered globally a cause of concern for public health. This report describes the first case of C. auris fungemia from a tertiary care hospital in the hilly state of Uttarakhand in India. Case report: The patient was a 37-year-old female who underwent a Whipple procedure for the carcinoma of the head of the pancreas. She developed fever 12 days after the operation while recovering from surgery in the hospital. Blood culture yielded C. auris which was identified by the matrix-assisted laser desorption/ionization-time of flight mass spectrometry (Bruker Daltonics, Germany). The patient was successfully treated with caspofungin. Conclusion: In conclusion, C. auris is potentially multidrug resistant, resulting in nosocomial outbreaks and sporadic infections which can be potentially prevented when identified early by implementing contact precautions.

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