scholarly journals Lost opportunities in Congenital Chagas disease: retrospective study in a high complexity hospital of La Plata city

2018 ◽  
Vol 73 ◽  
pp. 319
Author(s):  
D. Santonato ◽  
G. de la Parra ◽  
M. Lares ◽  
F. Argüello ◽  
P. Vizcarra ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Chagas Disease ◽  
High Complexity ◽  
La Plata ◽  
La Plata City

scholarly journals Adverse Events Associated with Nifurtimox Treatment for Chagas Disease in Children and Adults

2020 ◽  
Author(s):  
A. J. Berenstein ◽  
N. Falk ◽  
G. Moscatelli ◽  
S. Moroni ◽  
N. González ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Adverse Events ◽  
Chagas Disease ◽  
Adverse Drug Reactions ◽  
Drug Tolerance ◽  
Drug Reactions ◽  
Safety Concerns ◽  
Scarce Data

BACKGROUND: Nifurtimox (NF) is one of the only two drugs currently available for Chagas disease (ChD) treatment. However, there is scarce data on NF safety, and many physicians defer or refuse NF treatment because of concerns about drug tolerance. METHODS: Retrospective study of adverse drug reactions (ADRs) associated with NF treatment of ChD. Children received NF doses of 10-15 mg/kg/day for 60-90 days, and adults 8-10 mg/kg/day for 30 days. Results: 215 children (median age: 2.6yrs, range 0-17) and 105 adults (median age: 34yrs, range 18-57) were enrolled. Overall, 127/320 (39.7%) patients developed ADRs, with an incidence of 64/105 in adults, and 63/215 in children (OR = 3.7, 95%CI [2.2;6.3]). We observed 215 ADRs, 131 in adults (median: 2 events/patient (IQR25-75= 1-3) and 84 in children (median: 1 event/patient (IQR25-75= 1-1.5) (PAdjusted < 0.001). ADRs were mainly mild and moderate. Severe ADRs were infrequent (1.2% in children and 0.9% in adults). Nutritional, central nervous and digestive systems were the most frequently affected, without differences between both groups. Treatment was discontinued in 31/320 (9.7%) patients without differences between groups. However, ADR-related discontinuations occurred more frequently in adults than in children (OR = 5.5, 95%CI = [1.5;24]). CONCLUSIONS: Our study supports the safety of NF for ChD treatment. Delaying NF treatment due to safety concerns does not seem to be supported by the evidence.

scholarly journals Flooding risks and housing markets: a spatial hedonic analysis for La Plata City

2016 ◽  
Vol 21 (4) ◽  
pp. 464-489 ◽  
Author(s):  
Mariano Javier Rabassa ◽  
Juan Ignacio Zoloa
Keyword(s):  
Housing Markets ◽  
Hedonic Price ◽  
La Plata ◽  
Hedonic Price Models ◽  
Flooding Event ◽  
Hydraulic Infrastructure ◽  
Real Estate Prices ◽  
Spatial Hedonic Price Models ◽  
The City ◽  
La Plata City

AbstractOn 2 April 2013 a major flood struck the City of La Plata, Argentina, killing 89 people and displacing thousands of others. That event, the worst flood the city has suffered in the past 100 years, prompted plans for a new hydraulic infrastructure. Although such an investment is necessary, little is known about its benefits. This paper intends to shed some light on this issue by estimating the willingness to pay to avoid the risk of experiencing a flooding event. For this purpose, we have taken thousands of real estate prices in the La Plata Metropolitan Area and combined them with a high-resolution flood risks map to estimate spatial hedonic price models. The results show significant price discounting for properties in flood-prone areas.

scholarly journals Surgical treatment of relapsed megaesophagus

2020 ◽  
Vol 47 ◽  
Author(s):  
LUIGI CARLO DA SILVA COSTA ◽  
JOÃO GABRIEL ROMERO BRAGA ◽  
VALDIR TERCIOTI JUNIOR ◽  
JOÃO DE SOUZA COELHO NETO ◽  
JOSÉ ANTÔNIO POSSATTO FERRER ◽  
...  
Keyword(s):  
Weight Loss ◽  
Retrospective Study ◽  
Surgical Treatment ◽  
Postoperative Complications ◽  
Chagas Disease ◽  
Surgical Procedures ◽  
Postoperative Period ◽  
Outpatient Clinic ◽  
Surgical Result ◽  
Stage 1

ABSTRACT Objective: to analyze the surgical treatment of patients with recurrent megaesophagus followed at the esophageal-stomach-duodenal outpatient clinic of the Hospital de Clínicas - UNICAMP. Methods: a retrospective study, from 2011 to 2017, with 26 patients with Chagas or idiopathic megaesophagus, surgically treated, and who recurred with dysphagia. Clinical, endoscopic and radiographic aspects were assessed and correlated with the performed surgical procedures. Results: 50% had dysphagia for liquids, 69% regurgitation, 65.3% heartburn, 69.2% weight loss and 69.2% had Chagas disease. In addition, 38.4% had megaesophagus stage 1 and 2 and 61.5% stage 3 and 4. Regarding the reoperations, 53% of them underwent Heller-Pinotti surgery by laparoscopy, Serra-Dória in 30.7% and esophageal mucosectomy in 7.9%. In 72% of the reoperations there were no postoperative complications, and 80% of the patients had a good outcome, with reduction or elimination of dysphagia. Among the reoperated patients undergoing the laparoscopic Heller-Pinotti technique, three reported little improvement of dysphagia in the postoperative period and among those who underwent Serra-Dória surgery, 100% had no dysphagia. It was observed that, when the time between the first procedure and the reoperation was longer, the better the surgical result was, with statistical significant decreased dysphagia (p=0.0013, p<0.05). Conclusions: there was a preference to perform laparoscopic re-miotomy and, as a second option, Serra-Dória surgery, for patients with recurrent megaesophagus. Esophagectomy or esophageal mucosectomy were reserved for more severe patients.

scholarly journals Composition of the intestinal nematofauna of Anurogryllus muticus and Neocurtilla claraziana (Orthoptera) from pastures of La Plata city, Buenos Aires, Argentina

Caldasia ◽  
2020 ◽  
Vol 43 (1) ◽  
pp. 205-207
Author(s):  
José Matías Rusconi ◽  
María Fernanda Achinelly
Keyword(s):  
Buenos Aires ◽  
Entomopathogenic Nematode ◽  
Nematode Species ◽  
Parasitic Nematodes ◽  
La Plata ◽  
First Time ◽  
Prevalent Species ◽  
La Plata City ◽  
Orthopteran Species

The present study analyzes the intestinal nematofauna of the orthopteran species Anurogryllus muticus and Neocurtilla claraziana as part of a survey work conducted in pastures from the region of La Plata to isolate entomopathogenic nematode species. Eleven nematode species belonging to the families Thelastomatidae, Travassosinematidae, Cephalobidae, Rhabditidae, and Plectidae are reported. Parasitism percentages from 0.31 to 22.71 % were observed being Blatticola cristovata and Cephalobellus magalhaesi the most prevalent species. Cephalobium nitidum, Cruznema tripartitum, and Plectus parietinus are reported for the first time from Argentina. The findings of the study contribute to a better understanding of the biodiversity status of insect parasitic nematodes of the region.

scholarly journals Hand hygiene in high-complexity sectors as an integrating element in the combat of Sars-CoV-2

2020 ◽  
Vol 73 (suppl 2) ◽  
Author(s):  
Danielle Galdino de Paula ◽  
Marianna Ramos Francisco ◽  
Juliana Dias Freitas ◽  
Renata Christine Quintella Levachof ◽  
Bianca de Oliveira Fonseca ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Hand Hygiene ◽  
Health Professionals ◽  
Previous Analysis ◽  
Diagnostic Assessment ◽  
Medical Team ◽  
High Complexity ◽  
Hygiene Practices ◽  
Nursing Team ◽  
The Moment

ABSTRACT Objective: to perform a situational diagnosis of the behavior of health professionals concerning hand hygiene practices in highly-complex sectors. Methods: this quantitative and retrospective study was based on reports (2016 and 2017) of Adult and Pediatric ICUs of a Federal hospital in Rio de Janeiro. Results: one thousand two hundred fifty-eight opportunities for hand hygiene were analysed. The chance of professionals sanitizing hands in Pediatric ICUs is 41.61% higher than in Adult ICUs. Concerning proper hand hygiene, the medical team had a 39.44% lower chance than the nursing team. Others had a 30.62% lower chance when compared to the nursing team. The moment “after contact with the patient” presented 4.5275 times the chance in relation “before contact with the patient”. Conclusion: in front of hand hygiene recommendations to control COVID-19, diagnostic assessment and previous analysis of the behavior of professionals proved to be positive.

scholarly journals Itinerarios Urbanos Rockeros en la Ciudad de La Plata, Buenos Aires, Argentina

ILUMINURAS ◽  
2020 ◽  
Vol 21 (54) ◽  
Author(s):  
Josefina Cingolani
Keyword(s):  
Urban Space ◽  
Buenos Aires ◽  
Doctoral Thesis ◽  
La Plata ◽  
Data Production ◽  
The City ◽  
La Plata City ◽  
Methodological Strategy ◽  
The Way

Resumen: Este artículo recoge los resultados de una tesis doctoral realizada en el período 2013-2018, en donde se analiza la configuración del circuito de rock de la ciudad de La Plata. Retomando algunos resultados, aquí analizaremos los itinerarios de un conjunto de músicos/as integrantes del circuito, enfocándonos en sus trayectorias, en los trayectos que realizan en el espacio urbano y en las lógicas que organizan sus andares. Sostenemos como hipótesis que son las trayectorias de los actores las que modulan los trayectos que realizan, así como son esos recorridos espaciales los que poseen un carácter performativo sobre sus biografías. La estrategia metodológica será de tipo cualitativa, utilizando diversas herramientas de producción de datos, en donde se destaca la técnica de sombreo (Jirón, 2012). Asimismo, este artículo también brinda una reflexión sobre herramientas metodológicas para estudiar prácticas artísticas en la ciudad y su reciprocidad: el modo en que la ciudad condiciona las prácticas, las formas en que estas prácticas producen ciudad.Palabras Clave: Circuito. Rock. Trayectorias. Itinerarios Urbanos. Sombreo URBAN ROCKER ITINERARIES IN LA PLATA CITY, BUENOS AIRES, ARGENTINA. This article collects the results of a doctoral thesis carried out in the period 2013-2018, where the configuration of the circuit of rock in La Plata city. Returning to some results, here we will analyze the itineraries of a group of musicians who are members of the circuit, focusing on their trajectories, the journeys they make in the urban space and the logics that organize their gait. We hypothesize that it’s the trajectories of the actors that modulate the paths they make, as well as those spatial paths that have a performative character about their biographies. The methodological strategy will be qualitative, using various data production tools, where the shadow (Jirón, 2012) stands out as a technique.Likewise, this article also provides a reflection on methodological tools to study artistic practices in the city and their reciprocity: the way the city conditions practices, the ways in which these practices produce city.Keywords: Circuit. Rock. Trajectories. Urban Itineraries. Shadow

Sources, distribution and variability of airborne trace metals in La Plata City area, Argentina

2001 ◽  
Vol 111 (1) ◽  
pp. 149-158 ◽  
Author(s):  
C Bilos ◽  
J.C Colombo ◽  
C.N Skorupka ◽  
M.J Rodriguez Presa
Keyword(s):  
Trace Metals ◽  
City Area ◽  
La Plata ◽  
La Plata City

Secular changes in body size and body composition in schoolchildren from La Plata City (Argentina)

2014 ◽  
Vol 71 (3) ◽  
pp. 287-301 ◽  
Author(s):  
Luis Manuel Guimarey ◽  
Luis Eduardo Castro ◽  
María Fernanda Torres ◽  
María Florencia Cesani ◽  
María Antonia Luis ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Size ◽  
Secular Changes ◽  
La Plata ◽  
La Plata City
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