scholarly journals Population immunity for measles, rubella, mumps, and varicella among adults in Khanh Hoa province, Socialist Republic of Vietnam

2020 ◽  
Vol 101 ◽  
pp. 258
Author(s):  
M. Hachiya ◽  
T.H. Do ◽  
K.M. Huynh ◽  
Q.M. Vien ◽  
T.T. Hoang ◽  
...  
2020 ◽  
Author(s):  
Thai Hung Do ◽  
Kim Mai Huynh ◽  
Quang Mai Vien ◽  
Tien Thanh Hoang ◽  
Bao Trieu Nguyen ◽  
...  

Abstract Objective: Measles, rubella, mumps, and varicella are currently endemic in Vietnam, but population immunity to the four diseases among the general population has not been well investigated. This study measured specific immunoglobulin (Ig)G in 362 randomly selected adults between 20 and 70 years old, using residual serum samples to evaluate age-specific immunity to the four diseases in Khanh Hoa province.Results: Age-specific anti-measles IgG prevalence was lowest, at 89.3% (95% confidence interval 71.8–97.7%) at 20–24 years old, below the herd immunity threshold of 95% to prevent epidemics. About 71.4–90.3% of women of child-bearing age (20–49 years old) were seropositive for rubella, indicating that a certain proportion of babies are at risk of congenital rubella syndrome. A large proportion of young adults (20–29 years) are susceptible to mumps and varicella, with population immunity of 71.4–78.1% to mumps and 48.8–53.6% to varicella. Population-based seroprevalence surveys of both children and adults are needed to evaluate population immunity and improve current immunization programs by expanding the target ages for immunization and introducing new vaccines.


2020 ◽  
Vol 53 (1) ◽  
pp. 80-99
Author(s):  
Olesia Rozovyk

This article, based on archival documents, reveals resettlement processes in the Ukrainian Soviet Socialist Republic in 1932–34, which were conditioned by the repressive policy of the Soviet power. The process of resettlement into those regions of the Soviet Ukraine where the population died from hunger most, and which was approved by the authorities, is described in detail. It is noted that about 90,000 people moved from the northern oblasts of the Ukrainian SSR to the southern part of the republic. About 127,000 people arrived in Soviet Ukraine from the Byelorussian Soviet Socialist Republic (BSSR) and the western oblasts of the Russian Soviet Federative Socialist Republic (RSFSR). The material conditions of their residence and the reasons for the return of settlers to their previous places of inhabitance are described. I conclude that the resettlement policy of the authorities during 1932–34 changed the social and national composition of the eastern and southern oblasts of Ukraine.


Author(s):  
Ilkhomjon M. Saidov ◽  

The article is devoted to the participation of natives of the Uzbek Soviet Socialist Republic in the Baltic operation of 1944. The author states that Soviet historiography did not sufficiently address the problem of participation of individual peoples of the Soviet Union in the Great Patriotic War, and therefore their feat remained undervalued for a long time. More specifically, according to the author, 40–42% of the working age population of the Uzbek Soviet Socialist Republic fought on the fronts of the Great Patriotic War. Such figure was typical only for a limited number of countries participating in the anti-fascist coalition. Analyzing the participation of Soviet Uzbekistan citizens in the battles for the Baltic States, the author shows that the 51st and 71st guards rifle divisions, which included many natives of the Uzbek Soviet Socialist Republic, were particularly distinguished. Their heroic deeds were noted by the soviet leadership – a number of Uzbek guards were awarded the title of Hero of the Soviet Union. In addition, Uzbekistanis fought as part of partisan detachments – both in the Baltic States, Belarus, Ukraine, the Western regions of the Russian Soviet Federative Socialist Republic and Moldova. Many Uzbek partisans were awarded the medal “Partisan of the Patriotic War” of I and II degrees.


2018 ◽  
Vol 13 (1-2) ◽  
pp. 135-143
Author(s):  
Irina V. Rudneva

The article examines the issue of how, under the conditions of growing nationalism in the Socialist Republic of Croatia in the late 1960s, Miloš Žanko, one of the Croatian leaders, bravely opposed the political trends, which threatened both the region and his country. In the newspapers and magazines, at the Party congresses, he entered into harsh polemics with Croatian nationalists, who were exposing their insidious schemes and defending the idea of brotherhood and unity. However, Žanko did not anticipate how deeply nationalist ideology was rooted and how strong it was in Croatia, at what a high level of the establishment this ideology was supported, and what price the person who was daring to oppose it would have to pay.


BMC Medicine ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
C. N. Mburu ◽  
◽  
J. Ojal ◽  
R. Chebet ◽  
D. Akech ◽  
...  

Abstract Background The COVID-19 pandemic has disrupted routine measles immunisation and supplementary immunisation activities (SIAs) in most countries including Kenya. We assessed the risk of measles outbreaks during the pandemic in Kenya as a case study for the African Region. Methods Combining measles serological data, local contact patterns, and vaccination coverage into a cohort model, we predicted the age-adjusted population immunity in Kenya and estimated the probability of outbreaks when contact-reducing COVID-19 interventions are lifted. We considered various scenarios for reduced measles vaccination coverage from April 2020. Results In February 2020, when a scheduled SIA was postponed, population immunity was close to the herd immunity threshold and the probability of a large outbreak was 34% (8–54). As the COVID-19 contact restrictions are nearly fully eased, from December 2020, the probability of a large measles outbreak will increase to 38% (19–54), 46% (30–59), and 54% (43–64) assuming a 15%, 50%, and 100% reduction in measles vaccination coverage. By December 2021, this risk increases further to 43% (25–56), 54% (43–63), and 67% (59–72) for the same coverage scenarios respectively. However, the increased risk of a measles outbreak following the lifting of all restrictions can be overcome by conducting a SIA with ≥ 95% coverage in under-fives. Conclusion While contact restrictions sufficient for SAR-CoV-2 control temporarily reduce measles transmissibility and the risk of an outbreak from a measles immunity gap, this risk rises rapidly once these restrictions are lifted. Implementing delayed SIAs will be critical for prevention of measles outbreaks given the roll-back of contact restrictions in Kenya.


2019 ◽  
Vol 113 (11) ◽  
pp. 678-684 ◽  
Author(s):  
I-Ching Sam ◽  
Magelda Montoya ◽  
Chong Long Chua ◽  
Yoke Fun Chan ◽  
Andrew Pastor ◽  
...  

Abstract Background Zika virus (ZIKV) is believed to be endemic in Southeast Asia. However, there have been few Zika cases reported to date in Malaysia, which could be due to high pre-existing levels of population immunity. Methods To determine Zika virus (ZIKV) seroprevalence in Kuala Lumpur, Malaysia, 1085 serum samples from 2012, 2014–2015 and 2017 were screened for anti-ZIKV antibodies using a ZIKV NS1 blockade-of-binding assay. Reactive samples were confirmed using neutralization assays against ZIKV and the four dengue virus (DENV) serotypes. A sample was possible ZIKV seropositive with a ZIKV 50% neutralization (NT50) titre ≥20. A sample was probable ZIKV seropositive if, in addition, all DENV NT50 titres were <20 or the ZIKV NT50 titre was >4-fold greater than the highest DENV NT50 titre. Results We found low rates of possible ZIKV seropositivity (3.3% [95% confidence interval {CI} 2.4 to 4.6]) and probable ZIKV seropositivity (0.6% [95% CI 0.3 to 1.4]). Possible ZIKV seropositivity was independently associated with increasing age (odds ratio [OR] 1.04 [95% CI 1.02 to 1.06], p<0.0001) and male gender (OR 3.5 [95% CI 1.5 to 8.6], p=0.005). Conclusions The low ZIKV seroprevalence rate, a proxy for population immunity, does not explain the low incidence of Zika in dengue-hyperendemic Kuala Lumpur. Other factors, such as the possible protective effects of pre-existing flavivirus antibodies or reduced transmission by local mosquito vectors, should be explored. Kuala Lumpur is at high risk of a large-scale Zika epidemic.


Author(s):  
Silva Guljaš ◽  
Zvonimir Bosnić ◽  
Tamer Salha ◽  
Monika Berecki ◽  
Zdravka Krivdić Dupan ◽  
...  

Lack of knowledge and mistrust towards vaccines represent a challenge in achieving the vaccination coverage required for population immunity. The aim of this study is to examine the opinion that specific demographic groups have about COVID-19 vaccination, in order to detect potential fears and reasons for negative attitudes towards vaccination, and to gain knowledge on how to prepare strategies to eliminate possible misinformation that could affect vaccine hesitancy. The data collection approach was based on online questionnaire surveys, divided into three groups of questions that followed the main postulates of the health belief theory—a theory that helps understanding a behaviour of the public in some concrete surrounding in receiving preventive measures. Ordinary least squares regression analyses were used to examine the influence of individual factors on refusing the vaccine, and to provide information on the perception of participants on the danger of COVID-19 infection, and on potential barriers that could retard the vaccine utility. There was an equal proportion of participants (total number 276) who planned on receiving the COVID-19 vaccine (37%), and of those who did not (36.3%). The rest (26.7%) of participants were still indecisive. Our results indicated that attitudes on whether to receive the vaccine, on how serious consequences might be if getting the infection, as well as a suspicious towards the vaccine efficacy and the fear of the vaccine potential side effects, may depend on participants’ age (<40 vs. >40 years) and on whether they are healthcare workers or not. The barriers that make participants‘ unsure about of receiving the vaccine, such as a distrust in the vaccine efficacy and safety, may vary in different socio-demographic groups and depending on which is the point of time in the course of the pandemic development, as well as on the vaccine availability and experience in using certain vaccine formulas. There is a pressing need for health services to continuously provide information to the general population, and to address the root causes of mistrust through improved communication, using a wide range of policies, interventions and technologies.


Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 394
Author(s):  
Tatyana Ilyicheva ◽  
Vasily Marchenko ◽  
Olga Pyankova ◽  
Anastasia Moiseeva ◽  
Tran Thi Nhai ◽  
...  

To cause a pandemic, an influenza virus has to overcome two main barriers. First, the virus has to be antigenically new to humans. Second, the virus has to be directly transmitted from humans to humans. Thus, if the avian influenza virus is able to pass the second barrier, it could cause a pandemic, since there is no immunity to avian influenza in the human population. To determine whether the adaptation process is ongoing, analyses of human sera could be conducted in populations inhabiting regions where pandemic virus variant emergence is highly possible. This study aimed to analyze the sera of Vietnamese residents using hemagglutinin inhibition reaction (HI) and microneutralization (MN) with A/H5Nx (clade 2.3.4.4) influenza viruses isolated in Vietnam and the Russian Federation in 2017–2018. In this study, we used sera from 295 residents of the Socialist Republic of Vietnam collected from three groups: 52 samples were collected from households in Nam Dinh province, where poultry deaths have been reported (2017); 96 (2017) and 147 (2018) samples were collected from patients with somatic but not infectious diseases in Hanoi. In all, 65 serum samples were positive for HI, at least to one H5 virus used in the study. In MN, 47 serum samples neutralizing one or two viruses at dilutions of 1/40 or higher were identified. We postulate that the rapidly evolving A/H5Nx (clade 2.3.4.4) influenza virus is possibly gradually adapting to the human host, insofar as healthy individuals have antibodies to a wide spectrum of variants of that subtype.


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