Monopolar electrocautery tip vs plasma ablation in tonsillotomy: A randomized case-control study comparing outcomes in pediatric population

2021 ◽  
Vol 143 ◽  
pp. 110655
Author(s):  
Elie Bou Sanayeh ◽  
Samar Idriss ◽  
Youssef Farchakh ◽  
Charlie Hanna ◽  
Souheil Hallit ◽  
...  
Therapies ◽  
2020 ◽  
Vol 75 (5) ◽  
pp. 471-480
Author(s):  
Dominique Hillaire-Buys ◽  
Mégane Mousset ◽  
Marion Allouchery ◽  
Brahim Azzouz ◽  
Marina Babin ◽  
...  

2021 ◽  
Author(s):  
Hussein Naji ◽  
Aafia Mohammed Farooq Gheewale ◽  
Ebtesam Safi

Abstract BackgroundGastrostomy has become a common surgical procedure within the pediatric population with feeding difficulties and nutritional issues. In the aims of improving clinical outcomes, this research targets to compare the rate of complications of two different laparoscopic techniques of a gastrostomy button placement in a pediatric population: A combination of modified U-stitches and seldinger technique laparoscopic gastrostomy (MLG) versus the standard laparoscopic gastrostomy (LG).MethodsEighty-nine children were recruited for this retrospective case control study that assesses the surgical outcomes of a novel MLG, being the cases to the standard LG in children which are the controls. The main outcome measure is the rate of postoperative complications encompassing dislodgement of gastrostomy button, leak around button, local infection, and development of granulation tissue post-surgery which is compared between the two population groups.ResultsThe p-value of the study was shown to be 0.03 proving a statistical significance between the complication rates. ConclusionAs a result, the modified U-stitches laparoscopic gastrostomy has a lower rate of complications in comparison to the standard laparoscopic gastrostomy making it a better technique for gastrostomy placement in children.


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Chen Shen ◽  
Hui Qi ◽  
Lin Sun ◽  
Jing Xiao ◽  
Qing-qin Yin ◽  
...  

Background. IL-6 is a proinflammatory cytokine that plays a critical role in host defense against tuberculosis (TB). Genetic polymorphisms of IL-6 and its receptor IL-6R had been discussed in adult TB recently. However, their role in pediatric TB is still unclear. Due to the obvious differences in TB pathophysiology in children, which may also reflect differences in genetic background, further association studies in pediatric populations are needed.Methods. A case-control study was carried out in a Chinese pediatric population including 353 TB patients and 400 healthy controls. Tag-SNPs of IL-6 and IL-6R genes were selected by Haploview software, genotyped using MassArray, and analyzed statistically.Results. One polymorphism, rs2229238, in the 3’UTR region of IL-6R was observed to be associated with increased resistance to TB (adjustedP= 0.03). The rs2229238 T allele contributed to a reduced risk to TB in recessive heritable model (OR, 0.53; 95% CI, 0.35–0.78).Conclusions. By tag-SNP genotyping based case-control study, we identified a genetic polymorphism in the IL-6R 3’UTR that regulates host resistance to pediatric TB in a Chinese population.


2016 ◽  
Vol 26 (8) ◽  
pp. 831-837 ◽  
Author(s):  
Amanda Whippey ◽  
Gregory Kostandoff ◽  
Heung K. Ma ◽  
Ji Cheng ◽  
Lehana Thabane ◽  
...  

2021 ◽  
Author(s):  
Yolande Saab ◽  
Mirna Naccache ◽  
Rony Zeenny ◽  
Shereen Nabhani-Gebara ◽  
Lydia Sholy

Abstract Cancer is the most common cause of disease-related deaths in childhood. Many sociodemographic, socioeconomic, environmental and genetic risk factors have been associated with a childhood cancer risk. However, few to no such studies have been conducted in the Middle East including Lebanon. This is a population-based case-control study that was conducted in the Lebanese pediatric population. Data was collected through face- to-face interviews, using a questionnaire, with parents of children with cancer in Lebanese pediatric cancer centers over a two-year period. In total, the sample consisted of 322 participants. Results showed that there are several sociodemographic, socioeconomic, environmental factors, in addition to consanguinity between parents, level of education and occupation of the parents , area of residence of the child (location and proximity to high-voltage electrical networks, garbage disposal areas, industrial factories and high-ways) as well as sibling history of cancer are risk factors for childhood cancers in Lebanon. Conclusion: This study informs policy makers on the risk factors in order to find solution as well as policies to decrease and mitigate these risks.


2018 ◽  
Vol 108 ◽  
pp. 113-119 ◽  
Author(s):  
Maria Antonietta Collu ◽  
Eduard Esteller ◽  
Fiorella Lipari ◽  
Raul Haspert ◽  
Demetrio Mulas ◽  
...  

2020 ◽  
Vol 11 ◽  
Author(s):  
Maria-Grazia Lazzaroni ◽  
Laura Andreoli ◽  
Francesca Crisafulli ◽  
Francesco Tamborini ◽  
Irene Debeni ◽  
...  

Objective: The long-term outcome of children born to SLE mothers still represents a controversial topic in literature, with some studies reporting a possible increased prevalence of different neurologic and psychiatric diseases (NPD), including neurodevelopmental disorders (ND), and in particular learning disorders (LD). Different risk factors have been advocated, such as the in utero exposure to auto-antibodies and drugs, particularly Azathioprine (AZA).Methods: A case-control study was designed to compare pregnancies treated with AZA (cases) with those not treated with AZA (controls). All the pregnancies had been prospectively followed in two Italian centers. The match was based upon renal involvement, antiphospholipid (aPL) status, maternal age at pregnancy (±5 years) and child’s age at the time of the study (±2 years). SLE mothers were interviewed by a telephone survey, particularly focused on the presence of a certified NPD in their children ≥6 years of age.Results: Twenty-seven cases and 65 controls were similar in terms of demographic, immunological and clinical features, except for a higher rate of SLE flares during pregnancy in cases (22.2% vs. 10.8%, p:0.191). The 92 children had a mean age of 14.0 years at the time of the survey; 11 had at least one NPD (12.0%). The frequency of each single NPD was similar to that of the general pediatric population and no association was found with either the in utero exposure to AZA, or other specific factors (auto-antibodies, disease activity, obstetric complications, prematurity).Conclusion: The long-term neuropsychiatric outcome of the children born to SLE mothers did not show neither an increased frequency of NPD as compared to the general pediatric population nor a specific pattern of NPD. The in utero exposure to AZA was not associated with the development of NPD in this case-control study of prospectively-followed pregnancies. NPD are complex conditions and large prospective studies are needed to capture the wide range of variables that may contribute to their development in the offspring of SLE women.


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