Pulmonary tuberculosis: An analysis of isolation practices and clinical risk factors in a tertiary hospital

We aimed to evaluate sociodemographic, epidemiological, and clinical risk factors for pulmonary tuberculosis (PTB) in children presenting with severe acute malnutrition (SAM) and pneumonia. Children aged 0 to 59 months with SAM and radiologic pneumonia from April 2011 to July 2012 were studied in Bangladesh. Children with confirmed PTB (by culture and/or X-pert MTB/RIF) (cases = 27) and without PTB (controls = 81; randomly selected from 378 children) were compared. The cases more often had the history of contact with active PTB patient ( P < .01) and exposure to cigarette smoke ( P = .04) compared with the controls. In logistic regression analysis, after adjusting for potential confounders, the cases were independently associated with working mother ( P = .05) and positive tuberculin skin test (TST; P = .02). Thus, pneumonia in SAM children is a common presentation of PTB and further highlights the importance of the use of simple TST and/or history of contact with active TB patients in diagnosing PTB in such children, especially in resource-limited settings.

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In-Hospital Mortality Of Pulmonary Tuberculosis With Acute Respiratory Failure And Related Clinical Risk Factors

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases ◽

10.1016/j.jctube.2021.100236 ◽

2021 ◽

pp. 100236

Author(s):

Mia Elhidsi ◽

Menaldi Rasmin ◽

Prasenohadi

Keyword(s):

Risk Factors ◽

Respiratory Failure ◽

Pulmonary Tuberculosis ◽

Hospital Mortality ◽

Acute Respiratory Failure ◽

Clinical Risk Factors ◽

Clinical Risk

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Clinico-radiological variability of pulmonary tuberculosis in young patients as compared to elder patients prior to RNTCP and after 18 years RNTCP

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20182299 ◽

2018 ◽

Vol 6 (6) ◽

pp. 2116

Author(s):

Jawahar L. Joshi ◽

Sunita Devi ◽

Vinay Mohan ◽

Ritu P. Kaur ◽

Ramandeep Kaur

Keyword(s):

Risk Factors ◽

Pulmonary Tuberculosis ◽

Young Patients ◽

Clinical Risk Factors ◽

Clinical Risk ◽

Elder Patients ◽

Group A ◽

Group B ◽

Demographic Risk ◽

Demographic Risk Factors

Background: Tuberculosis, a chronic disease causing high morbidity and mortality with multiple host related and socio-demographic risk factors. Incidence is 3-4 times among in diabetics. HIV is considered to be a most powerful risk factor other being malnutrition, Tubercular contacts, smoking habits and alcoholism. Many ecological and societal threats increase a vulnerability to infection and succession of the disease. Objective was to study and compare various clinico-radiological presentations and clinical risk factors for pulmonary tuberculosis in the young (<50yrs) and elderly (>50yrs) patients.Methods: Total 300 pulmonary tuberculosis patients each admitted in hospital during 1999 (group ‘A’) and 2016 (group ‘B’) respectively were included in our study. Socio-demographic risk factors and presence of any existing co morbidities and clinical as well radiological presentation data were evaluated.Results: Majority patients in both group ‘A’ and ‘B’ were males (67% and 61.3%), younger (71.3% and 63.3%) patients. Elder patients had more smokers in both groups (48.8% and 33.6%). COPD trends seems to be receding in group ‘B’ as compared to group ‘A’ in younger (6.3% vs. 8.9%) as well elder (13.6% vs. 29.1%) but on the contrary lifestyle disease trends like DM increased in group ‘B’ than group ‘A’ patients more in elder subgroup (30% vs. 9.3%). HIV infected was more in younger 2.1 % (elder 0.9%) group ‘B’ patients. Haemoptysis (17.8% and 18.6% vs. 13.7% and 9.1%) and cough (~87% vs. ~85%) were almost similar but fever (~90% vs. ~65%) was seen significantly higher in the young patients. Radiologically bilateral upper lobe cavitations (15%-30%) was a higher in group A patients as compared to negligible less than ~3% cavitations in group B, on the contrary infiltrations (15%-32%) was more in group B.Conclusions: Young adults are more likely to have fever while haemoptysis cough and advanced lung field involvement is more common in elderly. Elderly patients had a higher number of co-morbidities like COPD and DM. The present study reveals that various demographic, socioeconomic and clinical risk factors have a potential role in causation/augmentation of pulmonary tuberculosis hence life style modification, prevention and timely management of these risk factors could be helpful to reduce the burden of disease.

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438 Predictive impact of clinical risk factors and the inducibility of ventricular fibrillation in patients with an asymptomatic Brugada-type ECG

EP Europace ◽

10.1016/s1099-5129(05)80290-9 ◽

2005 ◽

Vol 7 ◽

pp. 98-98

Keyword(s):

Risk Factors ◽

Ventricular Fibrillation ◽

Clinical Risk Factors ◽

Clinical Risk

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The impact of standard clinical risk factors on determination of optimal mammographic density cutpoints

10.26226/morressier.5ade45fdd462b8029238e7dc ◽

2018 ◽

Author(s):

Sian Iles

Keyword(s):

Risk Factors ◽

Mammographic Density ◽

Clinical Risk Factors ◽

Clinical Risk ◽

The Impact

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Faculty Opinions recommendation of Molecular and clinical risk factors for recurrence of skull base chordomas: gain on chromosome 2p, expression of brachyury, and lack of irradiation negatively correlate with patient prognosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718084150.793526065 ◽

2016 ◽

Author(s):

Carlos Bagley

Keyword(s):

Risk Factors ◽

Skull Base ◽

Clinical Risk Factors ◽

Clinical Risk ◽

Risk Factors For Recurrence ◽

Skull Base Chordomas ◽

Patient Prognosis

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Long-Term Follow-Up of Patients With Isolated Side Branch Coronary Artery Disease

Angiology ◽

10.1177/00033197211028024 ◽

2021 ◽

pp. 000331972110280

Author(s):

Sukru Arslan ◽

Ahmet Yildiz ◽

Okay Abaci ◽

Urfan Jafarov ◽

Servet Batit ◽

...

Keyword(s):

Risk Factors ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Vessel Diameter ◽

Side Branch ◽

Clinical Risk Factors ◽

Clinical Risk ◽

Artery Disease

The data with respect to stable coronary artery disease (SCAD) are mainly confined to main vessel disease. However, there is a lack of information and long-term outcomes regarding isolated side branch disease. This study aimed to evaluate long-term major adverse cardiac and cerebrovascular events (MACCEs) in patients with isolated side branch coronary artery disease (CAD). A total of 437 patients with isolated side branch SCAD were included. After a median follow-up of 38 months, the overall MACCE and all-cause mortality rates were 14.6% and 5.9%, respectively. Among angiographic features, 68.2% of patients had diagonal artery and 82.2% had ostial lesions. In 28.8% of patients, the vessel diameter was ≥2.75 mm. According to the American College of Cardiology lesion classification, 84.2% of patients had either class B or C lesions. Age, ostial lesions, glycated hemoglobin A1c, and neutrophil levels were independent predictors of MACCE. On the other hand, side branch location, vessel diameter, and lesion complexity did not affect outcomes. Clinical risk factors seem to have a greater impact on MACCE rather than lesion morphology. Therefore, the treatment of clinical risk factors is of paramount importance in these patients.

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