Dermoscopy of black skin: A cross-sectional study of clinical and dermoscopic features of melanocytic lesions in individuals with type V/VI skin compared to those with type I/II skin

2015 ◽  
Vol 73 (1) ◽  
pp. 114-119 ◽  
Author(s):  
Bruna Tuma ◽  
Sergio Yamada ◽  
Álvaro Nagib Atallah ◽  
Fernanda Mendes Araujo ◽  
Sergio Henrique Hirata
Rheumatology ◽  
2020 ◽  
Vol 59 (9) ◽  
pp. 2616-2624
Author(s):  
Svenja Henning ◽  
Wietske M Lambers ◽  
Berber Doornbos-van der Meer ◽  
Wayel H Abdulahad ◽  
Frans G M Kroese ◽  
...  

Abstract Objectives Incomplete SLE (iSLE) patients display symptoms typical for SLE but have insufficient criteria to fulfil the diagnosis. Biomarkers are needed to identify iSLE patients that will progress to SLE. IFN type I activation, B-cell-activating factor (BAFF) and B-cell subset distortions play an important role in the pathogenesis of SLE. The aim of this cross-sectional study was to investigate whether B-cell subsets are altered in iSLE patients, and whether these alterations correlate with IFN scores and BAFF levels. Methods iSLE patients (n = 34), SLE patients (n = 41) with quiescent disease (SLEDAI ≤4) and healthy controls (n = 22) were included. Proportions of B-cell subsets were measured with flow cytometry, IFN scores with RT-PCR and BAFF levels with ELISA. Results Proportions of age-associated B-cells were elevated in iSLE patients compared with healthy controls and correlated with IgG levels. In iSLE patients, IFN scores and BAFF levels were significantly increased compared with healthy controls. Also, IFN scores correlated with proportions of switched memory B-cells, plasma cells and IgG levels, and correlated negatively with complement levels in iSLE patients. Conclusion In this cross-sectional study, distortions in B-cell subsets were observed in iSLE patients and were correlated with IFN scores and IgG levels. Since these factors play an important role in the pathogenesis of SLE, iSLE patients with these distortions, high IFN scores, and high levels of IgG and BAFF may be at risk for progression to SLE.


2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Andre Luiz Ferreira Costa ◽  
Aline Kataki Paixão ◽  
Bianca Costa Gonçalves ◽  
Celso Massahiro Ogawa ◽  
Thiago Martinelli ◽  
...  

This study aimed to investigate the olfactory fossa according to the Keros classification using cone beam computed tomography. This cross-sectional study analysed cone beam computed tomography images selected from a database belonging to a radiology centre. The scans of 174 healthy patients were analysed by using the Xoran software. Gender, age, and side were correlated with the Keros classification. The mean age of the 174 patients was 45.3 years. The most prevalent Keros classification was type II (65.52%), followed by type III (20.69%) and type I (13.79%). No significant differences were found between Keros classification and the variables age, right side (pvalue = 0.4620), and left side (pvalue = 0.5709). There were also no significant differences between gender and the variables right side (pvalue = 0.1421) and left side (pvalue = 0.2136). Based on these results, we suggest that cone beam computed tomography can be recommended for analysis of the anterior skull base. Keros type II was the most prevalent type in our sample.


2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Samanta Daiana De Rossi ◽  
José Alexandre Mendonça ◽  
Penelope Ester Palominos ◽  
Charles Lubianca Kohem ◽  
Tania Ferreira Cestari ◽  
...  

Abstract Background Nail psoriasis occurs frequently in patients with psoriatic disease, it can lead to functional impairment, pain, discomfort, decreased quality of life and can also be a predictor for the development of arthritis. Early recognition of this condition can provide early and effective treatment and prevent structural impairment. This study aims to identify nail ultrasonographic characteristics in three groups: psoriasis (PsO), psoriatic arthritis (PsA) and controls patients, to determine if the ultrasonography (US) can identify early signs of nail psoriatic impairment or local inflammation. We conducted nail US to determine nail matrix resistance index (NMRI), nail bed resistance index (NBRI), and power Doppler (PD) and grayscale (GS) parameters in these 3 groups. Methods Single-center, cross-sectional study. GS, PD, and spectral doppler images of bilateral 2nd and 3rd fingernails were acquired from 35 PsO, 31 PsA, and 35 controls patients. An US equipment with an 18 MHz linear transducer for GS and 8.0 MHz for PD was used. PD, NMRI, NBRI, nail plate thickness (NPT), nail bed thickness (NBT), nail matrix thickness (NMT), and morphostructural characteristics of the trilaminar structure (TS) were evaluated in saved images, blind. Results Mean NMRI and NBRI did not differ between groups. Linear regression analysis detected no relationships between PsO or PsA and NMRI or NBRI. Nail PD grade did not differ between groups. Type I and IV TS changes were more frequent in PsO; types II and III changes were more frequent in PsA (p < 0.001). NPT was greater in PsA and PsO groups than controls: PsA 0.73 ± 0.14 mm, PsO 0.72 ± 0.15 mm, Controls 0.67 ± 0.10 mm (p = 0.001). Conclusion Echographic TS characteristics of the nail plate and NPT evaluated by GS are useful and can distinguish PsO and PsA nails from controls. NMRI, NBRI, and US nail microcirculation parameters could not distinguish psoriatic nails. Trial registration 72762317.4.0000.5327 (Certificate of Presentation of Ethical Appreciation – CAAE - Plataforma Brasil) Avaiable in https://plataformabrasil.saude.gov.br/login.jsf.


2014 ◽  
Vol 111 (2) ◽  
pp. S81
Author(s):  
Igor Nestrasil ◽  
Petr Bednarik ◽  
Brianna Yund ◽  
Kathleen Delaney ◽  
Victor Kovac ◽  
...  

2007 ◽  
Vol 23 (3) ◽  
pp. 365-371 ◽  
Author(s):  
Marina F. Caskey ◽  
Daniel J. Morgan ◽  
Aurelia F. Porto ◽  
Silvana P. Giozza ◽  
Andre L. Muniz ◽  
...  

2007 ◽  
Vol 7 (1) ◽  
Author(s):  
Paulo N Rocha ◽  
Ana Paula Rehem ◽  
Juliana F Santana ◽  
Neviton Castro ◽  
Andre L Muniz ◽  
...  

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Mei Yao ◽  
Yu Xia ◽  
Yijie Feng ◽  
Ying Ma ◽  
Yi Hong ◽  
...  

Abstract Background Spinal muscular atrophy (SMA) is a rare neurogenetic disease which involves multisystem dysfunctions such as respiratory, digestive, and motor disorders. Anxiety, depression and other psychological disorders often accompany severe chronic physical diseases. The aim of this study was to investigate the prevalence of anxiety and depression along with their influencing factors among school-age patients with SMA. Methods We conducted a cross-sectional study on school-age SMA patients in China. Patients aged 8–18 years with a genetic diagnosis of 5qSMA were invited to answer a questionnaire composed of sociodemographic and clinical questions, then to complete the Screen for Child Anxiety-Related Emotional Disorders and Depression Self-Rating Scale for depression and anxiety level evaluation. At the end of the questionnaire, further questions assessed the subjective anxiety and subjective depression of patients’ caregivers and their expectations for their child’s future. Results Complete data were available for 155 patients. The sample included 45.8% boys and 54.2% girls; 65.2% were type II, 27.1% were type III, and the remainder were type I SMA. Rates of anxiety and depression in these school-age SMA patients were 40.0% and 25.2%, respectively. Gender, age, and disease type were not associated with anxiety or depression, but respiratory system dysfunction, digestive system dysfunction, skeletal deformity, rehabilitation exercise, academic delay, specialized support from school, household income level, caregivers’ subjective anxiety, and caregivers’ expectations were significantly related to both anxiety and depression. Conclusions There was a high prevalence of anxiety and depression in school-age SMA patients in China. Professional psychological care maybe included in the standard of care. These results also call for possible targets for intervention such as reducing complications, improving drug accessibility, retaining normal schooling, strengthening school support, and enhancing the ability of the caregivers of SMA patients to assist in the diagnosis and treatment of the disease, so improving the mental health of SMA patients.


2021 ◽  
Vol 15 (10) ◽  
pp. 2663-2665
Author(s):  
Beenish Fatima Alam ◽  
Madiha Anwar ◽  
Kawish Syed ◽  
Tabassum Ahsan ◽  
Sikandar Javed Bajwa ◽  
...  

Aim: To determine the correlation between lip print, fingerprint form and blood groups that can be used for the identification of an individual among gender. Method: This cross-sectional study was conducted among 719 female and male participants with ages between 17-34 years from Bahria University Medical and Dental College. Patterns for lip and finger prints were collected along with the blood groups. SPSS v23 was used for statistical analysis. Frequency and percentages of the qualitative variables was calculated. The association of the variables was analyzed using Chi-square. Results: A total of 719 subjects, there were 327 males (45.5%) and 392 females (54.5%). Type I lip pattern was prevalent in 31.8% males followed by Type I’ in 27.6% females. The loop type of the finger print was observed in 165(50.5%) of males and 162(41.3%) females. The most common type of blood group was A+ in 27.2% in males while in females it was O+ in 29.8%. Conclusion: Individual parameters such as lip and finger prints along with blood groups can play an important role in personal identification of individual. In our study A+ blood group along with arch pattern of finger prints and Type I lip were most common patterns in males while in females Type I’lip pattern along with blood group 0+ and Loop pattern were common Keywords: Lip prints, Finger Prints, Cheiloscopy, Blood Groups, Forensic


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