scholarly journals Impact of comorbid anxiety disorders and obsessive–compulsive disorder on 24-month clinical outcomes of bipolar I disorder

2014 ◽  
Vol 166 ◽  
pp. 243-248 ◽  
Author(s):  
Sung-Wan Kim ◽  
Lesley Berk ◽  
Jayashri Kulkarni ◽  
Seetal Dodd ◽  
Anthony de Castella ◽  
...  
CNS Spectrums ◽  
2007 ◽  
Vol 12 (12) ◽  
pp. 913-919 ◽  
Author(s):  
Antonio Ciapparelli ◽  
Rosemma Paggini ◽  
Donatella Marazziti ◽  
Claudia Carmassi ◽  
Maria Bianchi ◽  
...  

ABSTRACTIntroductionComorbid anxiety disorders are frequently encountered in psychoses and mainly assessed during the hospitalization.MethodsComorbidity was investigated in 98 patients with schizophrenia, schizoaffective, or bipolar disorder, previously hospitalized for psychotic symptoms. Assessments, including Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Brief Psychiatric Rating Scale, and Clinical Global Impressions Scale, were performed during hospitalization (t0) and subsequently in a phase of remission (t1). Comorbidity was assessed at t1 only.ResultsOne or more comorbid anxiety diagnoses were made in 46 (46.9%) patients. Of these, 15 (32.6%) received multiple anxiety diagnoses, while 31 (67.4%) single anxiety diagnoses. Schizophrenic patients had a rate of social anxiety disorder (SAD) higher (P<.05) than the others. Patients assessed with panic disorder or with obsessive-compulsive disorder at t1 showed significantly greater severity of illness at t0; patients with SAD demonstrated greater severity at t1. No significant differences in the rates of individual anxiety disorders were found in patients treated with typical or atypical antipsychotics or with both.ConclusionAnxiety disorders, particularly obsessive-compulsive disorder, panic disorder and SAD, seem to be frequently comorbid in remitted psychotic patients; SAD would be more prevalent in schizophrenia and might negatively impact the course of the illness.


2014 ◽  
Author(s):  
David MB Christmas ◽  
Ian Crombie ◽  
Sam Eljamel ◽  
Naomi Fineberg ◽  
Bob MacVicar ◽  
...  

2019 ◽  
Vol 55 (8) ◽  
pp. 989-1000 ◽  
Author(s):  
Karin C. P. Remmerswaal ◽  
Neeltje M. Batelaan ◽  
Adriaan W. Hoogendoorn ◽  
Nic J. A. van der Wee ◽  
Patricia van Oppen ◽  
...  

Abstract Objective Patients with obsessive compulsive disorder (OCD) have high disease burden. It is important to restore quality of life (QoL) in treatment, so that patients become able to live a fulfilling life. Little is known about the longitudinal course of QoL in patients with OCD, its association with remission from OCD, and about factors that contribute to an unfavourable course of QoL in remitting patients. Methods Study on the 4-year course of QoL of patients with chronic (n = 144), intermittent (n = 22), and remitting OCD (n = 73) using longitudinal data of the Netherlands Obsessive Compulsive Disorder Association (NOCDA; complete data: n = 239; imputed data n = 382). The EuroQol five-dimensional questionnaire (EQ-5D) utility score was used to assess QoL. In patients with remitting OCD, we examined patient characteristics that contributed to an unfavourable course of QoL, including sociodemographics, OCD characteristics, psychiatric comorbidity, and personality traits. Results Course of QoL was associated with course of OCD. QoL improved in those who remitted from OCD; however, even in these patients, QoL remained significantly below the population norms. The correlation between QoL and severity of OCD was only moderate: r = − 0.40 indicating that other factors besides OCD severity contribute to QoL. In remitters, more severe anxiety and depression symptoms were related to a lower QoL. Results were similar in complete and imputed data sets. Conclusions Remission from OCD is associated with improvement of QoL, but comorbid anxiety and depression symptoms hamper the improvement of QoL. QoL could be improved by reducing OCD symptoms in patients with OCD and by treating comorbid anxiety and depression symptoms in remitting patients.


2010 ◽  
Vol 38 (6) ◽  
pp. 759-760
Author(s):  
William Eysenck ◽  
Michael W. Eysenck

In his theory of anxiety disorders, Eysenck (1997) argued that focus on one's own behavior is associated with social phobia, whereas focus on future-oriented threat cognitions is associated with obsessive-compulsive disorder. These foci occur in part because social phobics tend to be introverted and obsessive-compulsives either perceive themselves as having onerous responsibilities or actually do have them (e.g., women with infants). These assumptions have empirical support (Eysenck). We can use the theory to predict cross-cultural differences in anxiety disorders. Social phobia should be more common in introverted cultures. We correlated lifetime incidence of social phobia (data: Wittchen & Fehm, 2001) with extraversion (data: Steel & Ones, 2002) across several countries, obtaining the predicted negative correlation (-0.35). We will expand the database to establish definitively the strength of this association. We will also explore the prediction that people in individualistic countries (emphasizing personal responsibility) have a higher incidence of obsessive-compulsive disorder than those in collectivistic countries, a prediction receiving preliminary support (e.g., Essau, Sakano, Ishikawa, & Sasagawa, 2004).


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