scholarly journals Anxiety, depression, loneliness and social network in the elderly: Longitudinal associations from The Irish Longitudinal Study on Ageing (TILDA)

2019 ◽  
Vol 246 ◽  
pp. 82-88 ◽  
Author(s):  
Joan Domènech-Abella ◽  
Jordi Mundó ◽  
Josep Maria Haro ◽  
Maria Rubio-Valera
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Adriene M. Beltz ◽  
Amy M. Loviska ◽  
Alexander Weigard

AbstractTo what extent does gender expression vary day-to-day? Are daily changes related to psychological adjustment in the same way for all individuals? A person-specific approach was used to answer these questions in a 75-day intensive longitudinal study. Fifty-seven cisgender adults (27 women) provided over 4000 reports of daily masculinity and femininity and of three indices of internalizing problems. Results revealed: (a) substantial daily fluctuations in gender expression, especially in women; (b) sample-level links between daily increases in femininity or reductions in masculinity and heightened anxiety, depression, and self-reproach for men, but no apparent links for women; and (c) person-specific links between gender expression and psychological adjustment, such that some women reported internalizing problems with reduced masculinity (average male pattern) and some men reported problems with heightened masculinity (opposite the average male pattern). Findings highlight how intensive longitudinal research can illuminate the uniqueness of gender-related daily experiences, and their implications for the wellbeing of individuals.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lars Lind ◽  
Johan Sundström ◽  
Johan Ärnlöv ◽  
Ulf Risérus ◽  
Erik Lampa

AbstractThe impact of most, but not all, cardiovascular risk factors decline by age. We investigated how the metabolic syndrome (MetS) was related to cardiovascular disease (CVD) during 40 years follow-up in the Uppsala Longitudinal Study of Adult Men (ULSAM, 2,123 men all aged 50 at baseline with reinvestigations at age 60, 70, 77 and 82). The strength of MetS as a risk factor of incident combined end-point of three outcomes (CVD) declined with ageing, as well as for myocardial infarction, ischemic stroke and heart failure when analysed separately. For CVD, the risk ratio declined from 2.77 (95% CI 1.90–4.05) at age 50 to 1.30 (95% CI 1.05–1.60) at age 82. In conclusion, the strength of MetS as a risk factor of incident CVD declined with age. Since MetS was significantly related to incident CVD also at old age, our findings suggest that the occurrence of MetS in the elderly should not be regarded as innocent. However, since our data were derived in an observational study, any impact of MetS in the elderly needs to be verified in a randomized clinical intervention trial.


2011 ◽  
Vol 140 (5) ◽  
pp. 835-841 ◽  
Author(s):  
L. H. MORTENSEN ◽  
A. B. MAIER ◽  
P. E. SLAGBOM ◽  
G. PAWELEC ◽  
E. DERHOVANESSIAN ◽  
...  

SUMMARYHuman cytomegalovirus (CMV) is a common herpesvirus establishing lifelong persisting infection, which has been implicated in immunosenescence and mortality in the elderly. Little is known about how and when susceptibility to CMV infection is determined. We measured CMV seroprevalence in two genetically informative cohorts. From the Leiden Longevity Study (LLS) we selected long-lived sib-pairs (n=844) and their middle-aged offspring and the offspring's partners (n=1452). From the Longitudinal Study of Aging Danish Twins (LSADT) 604 (302 pairs) same-sex monozygotic (MZ) and dizygotic (DZ) twins aged 73–94 years were included (n=302 pairs). Offspring of the long-lived LLS participants had significantly lower seroprevalence of CMV compared to their partners (offspring: 42%vs. partners: 51%,P=0·003). Of 372 offspring living with a CMV-positive partner, only 58% were infected. The corresponding number for partners was 71% (P<0·001). In the LSADT, MZ and DZ twins had high and similar CMV-positive concordance rates (MZ: 90%vs. DZ: 88%,P=0·51) suggesting that shared family environment accounts for the similarity within twin pairs. Our findings suggest that susceptibility to CMV infection – even under continuous within-partnership exposure – appears to be more strongly influenced by early-life environment than by genetic factors and adult environment.


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