P3-179: Association between vitamin D concentration and dementia: A population-based cross-sectional study among elderly people in Southern Germany

2013 ◽  
Vol 9 ◽  
pp. P619-P619
Author(s):  
Christine von Arnim ◽  
Florian Herbolsheimer ◽  
Matthias Riepe ◽  
Thorsten Nikolaus ◽  
Michael Denkinger ◽  
...  
Keyword(s):  
Vitamin D ◽  
Elderly People ◽  
Population Based ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Southern Germany

scholarly journals Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014: a population-based cross-sectional study

2019 ◽  
Vol 59 (7) ◽  
pp. 3037-3044
Author(s):  
Eva Summerhays ◽  
Mats Eliasson ◽  
Robert Lundqvist ◽  
Stefan Söderberg ◽  
Tanja Zeller ◽  
...  
Keyword(s):  
Vitamin D ◽  
Time Trends ◽  
Time Trend ◽  
Population Based ◽  
Cross Sectional Study ◽  
Northern Sweden ◽  
Sectional Study ◽  
Cross Sectional ◽  
Potential Health ◽  
Entire Study

Abstract Purpose Vitamin D, produced through cutaneous photosynthesis or ingested via foods or supplements, has generated considerable research interest due to its potential health effects. However, epidemiological data on the time trends of vitamin D status are sparse, especially from northern Europe. We examined the time trend of vitamin D concentrations in northern Sweden between 1986 and 2014. Methods We used data on 11,129 men and women (aged 25–74 years) from seven population-based surveys (the Northern Sweden MONICA study), recruited between 1986 and 2014. Serum vitamin D (25-hydroxyvitamin D) status was measured using a one-step immunoassay (Abbott Architect). Multivariable linear regression models, adjusted for age, sex, and a number of other variables, were used to estimate the time trend of vitamin D concentrations. Results The mean value of vitamin D in the entire study population was 19.9 ng/mL [standard deviation (SD) 7.9], with lower values in men (19.4 ng/mL; SD 7.5) than in women (20.5 ng/mL; SD 8.2). Using the survey in 1986 as reference category, the multivariable-adjusted mean difference [95% confidence interval (CI)] in ng/mL was 2.7 (2.2, 3.3) in 1990, 3.2 (2.7, 3.7) in 1994, 1.6 (1.0, 2.1) in 1999, − 2.0 (− 2.5, − 1.4) in 2004, 1.0 (0.4, 1.5) in 2009, and 3.1 (2.5, 3.6) in 2014. Conclusion In this large cross-sectional study, we observed no clear upward or downward trend of vitamin D concentrations in northern Sweden between 1986 and 2014.

scholarly journals Bacteriuria and vitamin D deficiency: a cross sectional study of 385 nursing home residents

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Rebeka Arnljots ◽  
Egill Snaebjörnsson Arnljots ◽  
Jörgen Thorn ◽  
Marie Elm ◽  
Michael Moore ◽  
...  
Keyword(s):  
Vitamin D ◽  
Nursing Homes ◽  
Vitamin D Deficiency ◽  
Elderly People ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Blood Samples ◽  
The Mean ◽  
Urine Specimens

Abstract Background Up to half of elderly people at nursing homes have asymptomatic bacteriuria, and concentrations of 25-hydroxyvitamin D (25OHD) are generally low. Vitamin D is a modulator of the immune system and involved in protection of the epithelium in the urinary tract as well. The objective was to determine a possible association between bacteriuria and vitamin D deficiency among elderly people at nursing homes. Methods Cross-sectional study: Voided urine specimens and blood samples for cultivation and analysis of 25OHD were collected from elderly people at nursing homes in Sweden. Exclusion criteria were: urinary catheter, ongoing antibiotic treatment, incontinence or dementia too severe to provide a voided urine specimen or leave a blood sample, unwillingness to participate or terminal illness. Urine cultures and serum 25OHD concentrations were outcome measures and the association of bacteriuria with vitamin D deficiency was determined by logistic regression. Results Twenty-two nursing homes participated and 385 of 901elderly people provided voided urine specimens and blood samples. The mean age was 87 (SD 6.7), 69% women, 19% received vitamin D supplement, 13% had diabetes mellitus, and 54% were diagnosed with dementia. There was significant growth of potentially pathogenic bacteria in 32% (123/385) of voided urine specimens. Escherichia coli were present in 83% of positive urine cultures. The mean concentration of 25OHD in serum was 35 nmol/L (SD 21). Thirty-seven per cent (143/385) had 25OHD < 25 nmol/L, and 3.1% (12/385) 25OHD < 12.5 nmol/L. No association between bacteriuria and 25OHD < 25 nmol/L, OR 1.4 (0.86–2.3; p = 0.18) adjusted for age, gender, diabetes mellitus and dementia was found. However, if using 25OHD < 12.5 nmol/L as a cut-off for vitamin D deficiency the adjusted odds-ratio was 4.4 (1.1–17; p = 0.031). Conclusions Bacteriuria and vitamin D deficiency was common. No association between bacteriuria and 25OHD < 25 nmol/L was found. If using 25OHD < 12.5 nmol/L as cut-off for vitamin D deficiency there was an association. However, this has to be interpreted with caution as causality cannot be evaluated as well as only few residents had 25OHD < 12.5 nmol/L.

scholarly journals Implementation of an intervention to reduce population-based screening for vitamin D deficiency: a cross-sectional study

CMAJ Open ◽  
2017 ◽  
Vol 5 (1) ◽  
pp. E36-E39 ◽  
Author(s):  
Christopher Naugler ◽  
Brenda Hemmelgarn ◽  
Hude Quan ◽  
Fiona Clement ◽  
Tolulope Sajobi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Population Based ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Prevalence and Determinants of Vitamin D Deficiency in 9595 Mongolian Schoolchildren: A Cross-Sectional Study

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4175
Author(s):  
Jorick Bater ◽  
Sabri Bromage ◽  
Tuyatsetseg Jambal ◽  
Enkhjargal Tsendjav ◽  
Enkhsaikhan Lkhagvasuren ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Parental Education ◽  
Northeast Asia ◽  
Female Gender ◽  
Population Based ◽  
Cross Sectional Study ◽  
Capital City ◽  
Sectional Study ◽  
Cross Sectional

Population-based data relating to vitamin D status of children in Northeast Asia are lacking. We conducted a cross-sectional study to determine the prevalence and determinants of vitamin D deficiency in 9595 schoolchildren aged 6–13 years in Ulaanbaatar (UB), the capital city of Mongolia. Risk factors for vitamin D deficiency were collected by questionnaire, and serum 25-hydroxyvitamin D (25[OH]D) concentrations were measured using an enzyme-linked fluorescent assay, standardized and categorized as deficient (25[OH]D <10 ng/mL) or not. Odds ratios for associations between independent variables and risk of vitamin D deficiency were calculated using multivariate analysis with adjustment for potential confounders. The prevalence of vitamins D deficiency was 40.6% (95% CI 39.7% to 41.6%). It was independently associated with female gender (adjusted odds ratio [aOR] for girls vs. boys 1.23, 95% CI 1.11–1.35), month of sampling (aORs for December–February vs. June–November 5.28 [4.53–6.15], March–May vs. June–November 14.85 [12.46–17.74]), lower levels of parental education (P for trend <0.001), lower frequency of egg consumption (P for trend <0.001), active tuberculosis (aOR 1.40 [1.03–1.94]), household smoking (aOR 1.13 [1.02 to1.25]), and shorter time outdoors (P for trend <0.001). We report a very high prevalence of vitamin D deficiency among Mongolian schoolchildren, which requires addressing as a public health priority.

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