Matrix effect-free on-line pass-through cleanup procedure for the fast determination of local anesthetic drug by LC-MS/MS

2019 ◽  
Vol 1130-1131 ◽  
pp. 121831 ◽  
Author(s):  
Li-Ming Zhao ◽  
Lu Gan ◽  
Yun Zhang
Keyword(s):  
Local Anesthetic ◽  
Matrix Effect ◽  
Anesthetic Drug ◽  
Fast Determination ◽  
Cleanup Procedure ◽  
On Line ◽  
Pass Through ◽  
Local Anesthetic Drug

Fast determination of fipronil and its metabolites in seafood using PRiME pass-through cleanup followed by isotope dilution UHPLC-MS/MS

2018 ◽  
Vol 10 (15) ◽  
pp. 1673-1679 ◽  
Author(s):  
Yun Zhang ◽  
Yong-Gang Zhao ◽  
He-Li Cheng ◽  
Nadeem Muhammad ◽  
Wei-Sheng Chen ◽  
...  
Keyword(s):  
Isotope Dilution ◽  
Fast Determination ◽  
Cleanup Procedure ◽  
Pass Through

A simple and effective method based on the PRiME pass-through cleanup procedure followed by UHPLC-MS/MS was developed for analyzing fipronil and its metabolites in seafoods.

Multiply-functionalized graphene oxide on-line pass-through cleanup for the fast determination of aconitum alkaloids in human plasma by LC-MS/MS

2019 ◽  
Vol 11 (25) ◽  
pp. 3144-3149 ◽  
Author(s):  
Shi-Wei He ◽  
Yun Zhang ◽  
Yong-Gang Zhao ◽  
Ming-Li Ye ◽  
Yan Zhu
Keyword(s):  
Ionic Liquid ◽  
Graphene Oxide ◽  
Human Plasma ◽  
Functionalized Graphene ◽  
Functionalized Graphene Oxide ◽  
Fast Determination ◽  
Aconitum Alkaloids ◽  
On Line ◽  
Pass Through

A novel ionic liquid coupled with nano-titania coated modified magnetic GO composites (IL-Ti-Mag-GO) has been synthesized.

scholarly journals Fluorimetric Method for the Determination of Histidine in Random Human Urine Based on Zone Fluidics

Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1665
Author(s):  
Antonios Alevridis ◽  
Apostolia Tsiasioti ◽  
Constantinos K. Zacharis ◽  
Paraskevas D. Tzanavaras
Keyword(s):  
Matrix Effect ◽  
Human Urine ◽  
Basic Medium ◽  
Medium Ph ◽  
Line Flow ◽  
On Line ◽  
Adult Volunteers ◽  
Fluorescent Derivative ◽  
Better Than

In the present study, the determination of histidine (HIS) by an on-line flow method based on the concept of zone fluidics is reported. HIS reacts fast with o-phthalaldehyde at a mildly basic medium (pH 7.5) and in the absence of additional nucleophilic compounds to yield a highly fluorescent derivative (λex/λem = 360/440 nm). The flow procedure was optimized and validated, paying special attention to its selectivity and sensitivity. The LOD was 31 nmol·L−1, while the within-day and day-to-day precisions were better than 1.0% and 5.0%, respectively (n = 6). Random urine samples from adult volunteers (n = 7) were successfully analyzed without matrix effect (<1%). Endogenous HIS content ranged between 116 and 1527 μmol·L−1 with percentage recoveries in the range of 87.6%–95.4%.

Accidental intoxication of the fetus with local anesthetic drug during caudal anesthesia

1965 ◽  
Vol 92 (7) ◽  
pp. 922-924 ◽  
Author(s):  
Mieczyslaw Finster ◽  
Paul J. Poppers ◽  
John C. Sinclair ◽  
Hisayo O. Morishima ◽  
Salha S. Daniel
Keyword(s):  
Local Anesthetic ◽  
Anesthetic Drug ◽  
Caudal Anesthesia ◽  
Local Anesthetic Drug

The Use of Dye Surrogates to Illustrate Local Anesthetic Drug Sequestration by Lipid Emulsion

2012 ◽  
Vol 37 (2) ◽  
pp. 183-187 ◽  
Author(s):  
Aikaterini Papadopoulou ◽  
Johann W. Willers ◽  
Theophilus L. Samuels ◽  
David R. Uncles
Keyword(s):  
Local Anesthetic ◽  
Lipid Emulsion ◽  
Anesthetic Drug ◽  
Drug Sequestration ◽  
Local Anesthetic Drug
Sign in / Sign up

Export Citation Format

Share Document