A cross-sectional study on the effect of dendritic cell therapy on the survival of patients with advanced stage epithelial ovarian cancer

Cytotherapy ◽  
2018 ◽  
Vol 20 (5) ◽  
pp. S100-S101
Author(s):  
M.P. Evangelista ◽  
M.J. De Vera ◽  
G. Aligui ◽  
R.O. Campos
Author(s):  
Risma Maharani ◽  
Syahrul Rauf ◽  
Rina Masadah

Objective: To determine the expression of Phosphatase Regenerating Liver-3 (PRL-3) and E-Cadherin in the epithelial ovarian cancer on various stages and differentiation grades. Method: This was a cross-sectional study design conducted at Obstetrics and Gynecology Department of several teaching hospitals, Faculty of Medicine Universitas Hasanuddin from January to June 2015. The expression of PRL-3 and E-cadherin was assessed immunohistochemically in 40 patients with epithelial ovarian cancer including 15 patients in early stage and 25 patients in advanced stage. We used the Fisher’s exact test with the significance of p0.05). The significant difference was found in the expression of E-cadherin whereas the high expression was shown at early stage than advanced stage (p0.05). This study also pointed out no correlation between the expression of PRL-3 and E-cadherin in epithelial ovarian cancer (p>0.05). Conclusion: PRL-3 overexpression does not decrease E-cadherin expression in epithelial ovarian cancer. Keywords: E-cadherin, epithelial ovarian cancer, PRL-3


Author(s):  
Hariyono Winarto ◽  
Ken Indra

Objective: Studies regarding omentectomy on epithelialovarian cancer are scarce with conflicting results; this study isaimed to investigate the prevalence of occult metastases inpatients with epithelial ovarian cancer of the omentum.Methods: A cross-sectional study design was used by evaluating themedical records of surgically staged ovarian cancer patients in Dr.Cipto Mangunkusumo Hospital, Jakarta, Indonesia during the periodof January 2009 to December 2015.Results: A total of 51 subjects were involved in this study. One(2%) of 51 subjects was found to have occult metastases in theomentum. The prevalence of metastases of early stage epithelialovarian cancer in 2009-2015 is 33.3% (17 out of 51 subjects),whereas the omental involvement is found only in 2% subjects(1 out of 51).Conclusion: The prevalence of occult metastases of early stageepithelial ovarian cancer in Dr. Cipto Mangunkusumo Hospital,Jakarta, Indonesia, from 2009-2015 in 2% (1/51 subjects).[Indones J Obstet Gynecol 2018; 6-2: 119-122]Keywords: cancer, epithelial, metastases, omentum, ovarian cancer,ovary, prevalence


2020 ◽  
Vol 9 (1) ◽  
pp. 125
Author(s):  
Teguh Prakosa ◽  
Ambar Mudigdo ◽  
Bambang Purwanto ◽  
Brian Wasita ◽  
Risya Cilmiaty ◽  
...  

2018 ◽  
Vol 6 (3) ◽  
pp. 121-124
Author(s):  
Seyedeh Razieh Hashemi ◽  
Mohammad Hossein Khosravi ◽  
Mohammad Ali Hosseini ◽  
Rezvan Ashkesh ◽  
Afsaneh Lalooei

Introduction: Involving approximately 4% of malignancies in women, ovarian cancer remains one of the most fatal cancers. However, it is important to consider conditions which are not primary ovarian diseases, but mimic their behaviors. In the present study, the epidemiological characteristics of extra-ovarian conditions mimicking ovarian masses are evaluated. Methods: This cross-sectional study was conducted on patients with a primary diagnosis of ovarian mass who underwent surgery by gynecologists between January 2012 and March 2016. The surgeon’s primary diagnosis and the final histopathology assessment report were evaluated for each patient. In cases where the final histopathology report was not in the spectrum of gynecologic pathology, possible reasons for incompatibility were investigated. Results: Ultimately, 1876 patients with a mean age of 48.26±15.4 years underwent analysis. Among these patients, 27 (1.4%) had masses of a non-gynecologic origin. The final diagnoses were divided into four main categories: masses with a gastrointestinal origin (55.5%), infectious (18.5%), those with a retroperitoneal origin (18.5%), and embryologic-origin masses (7.4%). Conclusion: The results suggest that extra-ovarian diseases should be considered in differential diagnoses of patients with a primary diagnosis of ovarian cancer. Furthermore, it was found that metastases from gastrointestinal tract tumors and infectious diseases are the most common pathologies among extra-ovarian conditions.


2020 ◽  
Vol 29 (4) ◽  
pp. 582
Author(s):  
EmmanuelObiora Izuka ◽  
ObinnaChinedu Nwafor ◽  
JosephTochukwu Enebe ◽  
IfeanyichukwuJude Ofor ◽  
ChineloElizabeth Obiora-Izuka ◽  
...  

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