Theoretical assessment of the impact of noise on heuristic parameter inference methods for surface-confined non-catalytic voltammetry experiments

2021 ◽  
pp. 115927
Author(s):  
Henry O. Lloyd-Laney ◽  
Martin J. Robinson ◽  
Alison Parkin ◽  
David J. Gavaghan
Keyword(s):  
Parameter Inference ◽  
Inference Methods ◽  
The Impact ◽  
Theoretical Assessment

scholarly journals Theoretical Assessment of the Impact of Climatic Factors in a Vibrio Cholerae Model

2018 ◽  
Vol 66 (4) ◽  
pp. 279-291 ◽  
Author(s):  
G. Kolaye ◽  
I. Damakoa ◽  
S. Bowong ◽  
R. Houe ◽  
D. Békollè
Keyword(s):  
Vibrio Cholerae ◽  
Climatic Factors ◽  
The Impact ◽  
Theoretical Assessment

scholarly journals Genome-scale data resolve ancestral rock-inhabiting lifestyle in Dothideomycetes (Ascomycota)

IMA Fungus ◽  
2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Claudio G. Ametrano ◽  
Felix Grewe ◽  
Pedro W. Crous ◽  
Stephen B. Goodwin ◽  
Chen Liang ◽  
...  
Keyword(s):  
Character State ◽  
Ancestral Character State ◽  
Wide Range ◽  
Tree Inference ◽  
Ancestral Character State Reconstruction ◽  
Inference Methods ◽  
Genome Scale ◽  
The Impact ◽  
Rock Inhabiting Fungi ◽  
Scale Data

Abstract Dothideomycetes is the most diverse fungal class in Ascomycota and includes species with a wide range of lifestyles. Previous multilocus studies have investigated the taxonomic and evolutionary relationships of these taxa but often failed to resolve early diverging nodes and frequently generated inconsistent placements of some clades. Here, we use a phylogenomic approach to resolve relationships in Dothideomycetes, focusing on two genera of melanized, extremotolerant rock-inhabiting fungi, Lichenothelia and Saxomyces, that have been suggested to be early diverging lineages. We assembled phylogenomic datasets from newly sequenced (4) and previously available genomes (238) of 242 taxa. We explored the influence of tree inference methods, supermatrix vs. coalescent-based species tree, and the impact of varying amounts of genomic data. Overall, our phylogenetic reconstructions provide consistent and well-supported topologies for Dothideomycetes, recovering Lichenothelia and Saxomyces among the earliest diverging lineages in the class. In addition, many of the major lineages within Dothideomycetes are recovered as monophyletic, and the phylogenomic approach implemented strongly supports their relationships. Ancestral character state reconstruction suggest that the rock-inhabiting lifestyle is ancestral within the class.

scholarly journals On the impact of model selection on predictor identification and parameter inference

2016 ◽  
Vol 32 (2) ◽  
pp. 667-690 ◽  
Author(s):  
Ruth M. Pfeiffer ◽  
Andrew Redd ◽  
Raymond J. Carroll
Keyword(s):  
Model Selection ◽  
Parameter Inference ◽  
The Impact

scholarly journals Theoretical assessment of the response of an explosive charge to the impact of a tungsten subprojectile

2020 ◽  
pp. 17-28
Author(s):  
Waldemar Trzciński
Keyword(s):  
Explosive Charge ◽  
High Speed ◽  
Projectile Impact ◽  
The Impact ◽  
Theoretical Assessment

The criteria for initiation of detonation in an explosive encased in a metal envelope following impact by a projectile are discussed in the paper. Methods for estimating the pressure in the explosive after impact by a high-speed projectile are presented. The methods and criteria were used to investigate the response of explosives encased in steel shells after tungsten projectile impact. Based on the results obtained, the ability of AHEAD ammunition to destroy missiles and artillery shells was assessed.

scholarly journals The impact of experimental design choices on parameter inference for models of growing cell colonies

2018 ◽  
Vol 5 (8) ◽  
pp. 180384 ◽  
Author(s):  
Andrew Parker ◽  
Matthew J. Simpson ◽  
Ruth E. Baker
Keyword(s):  
Experimental Design ◽  
Cell Tracking ◽  
Colony Growth ◽  
Motile Cell ◽  
Cell Populations ◽  
Model Parameters ◽  
Parameter Inference ◽  
Growing Cell ◽  
The Impact ◽  
Cell Colony

To better understand development, repair and disease progression, it is useful to quantify the behaviour of proliferative and motile cell populations as they grow and expand to fill their local environment. Inferring parameters associated with mechanistic models of cell colony growth using quantitative data collected from carefully designed experiments provides a natural means to elucidate the relative contributions of various processes to the growth of the colony. In this work, we explore how experimental design impacts our ability to infer parameters for simple models of the growth of proliferative and motile cell populations. We adopt a Bayesian approach, which allows us to characterize the uncertainty associated with estimates of the model parameters. Our results suggest that experimental designs that incorporate initial spatial heterogeneities in cell positions facilitate parameter inference without the requirement of cell tracking, while designs that involve uniform initial placement of cells require cell tracking for accurate parameter inference. As cell tracking is an experimental bottleneck in many studies of this type, our recommendations for experimental design provide for significant potential time and cost savings in the analysis of cell colony growth.

Theoretical Assessment of the Impact of Cooling and Recovery Systems on Energy Efficiency of Compressor Units Based on Long Stroke Piston Stages

2020 ◽  
pp. 35-44
Author(s):  
V.L. Yusha ◽  
S.S. Busarov ◽  
G.I. Chernov
Keyword(s):  
Rankine Cycle ◽  
Thermal Mode ◽  
Gas Temperature ◽  
Working Process ◽  
External Cooling ◽  
Discharge Temperature ◽  
Discharge Pressure ◽  
Long Stroke ◽  
The Impact ◽  
Theoretical Assessment

At present, piston and membrane compressor units in the range of medium and high pressure (3.0–10.0 MPa and more) and low productivity (0.001–0.03 m3/s) retain their competitiveness. Their technical characteristics can be improved in many ways, for example, by using long stroke stages. In one such stage, the gas pressure can be increased from 0.1 to 3.0–11.0 MPa without exceeding temperature limits. One of the research directions of such stages is to determine the most efficient thermal mode of operation of the stage. A ‘quasi-isothermal’ working process of compression with intensive external cooling of the cylinder and a ‘quasi-adiabatic’ working process of compression without intensive external cooling of the cylinder are considered as possible options. The article presents the results of a theoretical assessment of the effectiveness of the use of cooling and recovery systems in compressor units based on long-stroke piston stages. The possibility of providing a mode where the discharge gas temperature differs from the gas temperature at suction by 40–80 K is shown. This should be considered a good achievement for the 30–100 ratio of the discharge pressure to the suction pressure. A theoretical possibility of increasing the discharge temperature up to 500–900 K is shown, which makes it possible to effectively apply the heat recovery system of compressed gases based on the Rankine cycle.

scholarly journals Digital Media and Democracy: A Systematic Review of Causal and Correlational Evidence Worldwide

2021 ◽  
Author(s):  
Philipp Lorenz-Spreen ◽  
Lisa Oswald ◽  
Stephan Lewandowsky ◽  
Ralph Hertwig
Keyword(s):  
Systematic Review ◽  
Digital Media ◽  
Political System ◽  
Political Trust ◽  
Emerging Democracies ◽  
Several Variables ◽  
Inference Methods ◽  
Established Democracies ◽  
The Impact ◽  
Political Variables

One of today's most controversial and consequential questions is whether the rapid, worldwide uptake of digital media is causally related to a decline in democracy. We conducted a systematic review of causal and correlational evidence (N=498 articles) on the link between digital media and different political variables, such as trust, polarization or news consumption. We further focused on the subset of articles that employed causal inference methods. Across methods, the articles report associations between digital media use and most political variables. Some associations, such as increases in political participation and information consumption, are likely to be beneficial for democracy and were often observed in the Global South and emerging democracies. Other consistently reported associations, such as declining political trust, advantages for populists, and growing polarization, are likely to be detrimental to democracy and were more pronounced in established democracies. We conclude that while the impact of digital media on democracy depends on the specific political variable and the political system in question, several variables show clear directions of associations. We believe that the evidence calls for further research efforts and vigilance by governments and civil societies to better understand and actively design the intimate interplay of digital media and democracy.

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