Deciphering biochemical basis of Qingkailing injection-induced anaphylaxis in a rat model by time-dependent metabolomic profiling based on metabolite polarity-oriented analysis

2018 ◽  
Vol 225 ◽  
pp. 287-296 ◽  
Author(s):  
Xiaoyan Gao ◽  
Lingling Qin ◽  
Zhixin Zhang ◽  
Huizhen Zhao ◽  
Wenjuan Zhou ◽  
...  
Keyword(s):  
Rat Model ◽  
Time Dependent ◽  
Biochemical Basis ◽  
Metabolomic Profiling ◽  
Qingkailing Injection

Time-dependent changes in inflammatory markers in a rat model of colitis by leisure sport activity

2013 ◽  
Vol 51 (05) ◽  
Author(s):  
Z Szalai ◽  
K Kupai ◽  
A Magyariné Berkó ◽  
A Pósa ◽  
R Szabó ◽  
...  
Keyword(s):  
Rat Model ◽  
Inflammatory Markers ◽  
Sport Activity ◽  
Time Dependent

Metabolomic profiling of urine-derived extracellular vesicles from rat model of drug-induced acute kidney injury

2021 ◽  
Vol 546 ◽  
pp. 103-110
Author(s):  
Masayoshi Saito ◽  
Satoshi Horie ◽  
Hidenori Yasuhara ◽  
Akane Kashimura ◽  
Eiji Sugiyama ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Extracellular Vesicles ◽  
Rat Model ◽  
Kidney Injury ◽  
Drug Induced ◽  
Metabolomic Profiling

Rat model of pulmonary arteriovenous malformations after right superior cavopulmonary anastomosis

2002 ◽  
Vol 283 (5) ◽  
pp. H2151-H2156 ◽  
Author(s):  
Sandra L. Starnes ◽  
Brian W. Duncan ◽  
Charles H. Fraga ◽  
Shailesh Y. Desai ◽  
Thomas K. Jones ◽  
...  
Keyword(s):  
Von Willebrand Factor ◽  
Rat Model ◽  
Microvessel Density ◽  
Arteriovenous Malformations ◽  
Pulmonary Angiography ◽  
Time Dependent ◽  
Pulmonary Arteriovenous Malformations ◽  
Cavopulmonary Anastomosis ◽  
Von Willebrand ◽  
Willebrand Factor

We developed a rat model of pulmonary arteriovenous malformations after cavopulmonary anastomosis. We sought to determine whether this model reproduces the angiographic and histologic features seen in the human condition. Eight Sprague-Dawley rats underwent a right superior cavopulmonary anastomosis with the use of microsurgical techniques. Between 2 and 13 mo, pulmonary angiography was performed, the animals were euthanized, and the lungs were removed. Microscopic sections of the lung were stained with an endothelial-specific antibody (von Willebrand factor). Microvessel density was determined by counting vessels staining positively for von Willebrand factor, and the shunted and nonshunted (control) lungs were compared for each animal. Pulmonary angiography revealed time-dependent development of arteriovenous malformations. Microvessel density demonstrated a time-dependent increase in the shunted lung compared with the control lung (simple linear regression of the ratio of the microvessel density of the shunted lung divided by the microvessel density of the control lung on time; R 2 = 0.79, P = 0.003). This animal model reproduces the same angiographic and microscopic features of pulmonary arteriovenous malformations that develop in humans after cavopulmonary anastomosis. This appears to be a valid model that may be used to further study etiologic mechanisms for this phenomenon.

scholarly journals 1034 TIME-DEPENDENT CHANGES IN BLADDER FUNCTION AND PLANTAR SENSITIVITY IN A RAT MODEL OF FIBROMYALGIA INDUCED BY HYDROCHLORIC ACID INJECTION INTO THE GLUTEUS

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Akira Furuta ◽  
Yasuyuki Suzuki ◽  
Yusuke Koike ◽  
Takehito Naruoka ◽  
Nozomu Furuta ◽  
...  
Keyword(s):  
Hydrochloric Acid ◽  
Rat Model ◽  
Time Dependent ◽  
Bladder Function ◽  
Acid Injection

Metabolomic profiling of the autosomal dominant polycystic kidney disease rat model

2011 ◽  
Vol 15 (5) ◽  
pp. 676-687 ◽  
Author(s):  
Takafumi Toyohara ◽  
Takehiro Suzuki ◽  
Yasutoshi Akiyama ◽  
Daisuke Yoshihara ◽  
Yoichi Takeuchi ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Rat Model ◽  
Autosomal Dominant ◽  
Polycystic Kidney ◽  
Metabolomic Profiling ◽  
Autosomal Dominant Polycystic Kidney

The effects of Labisia pumila on postmenopausal osteoporotic rat model: Dose and time-dependent micro-CT analysis

2014 ◽  
Vol 22 (4) ◽  
pp. 503-518 ◽  
Author(s):  
Nadia Mohd Effendy ◽  
Mohd Fadhli Khamis ◽  
Ima Nirwana Soelaiman ◽  
Ahmad Nazrun Shuid
Keyword(s):  
Rat Model ◽  
Time Dependent ◽  
Micro Ct ◽  
Ct Analysis ◽  
Labisia Pumila

Time-dependent effect of oligomeric amyloid-β (1–42)-induced hippocampal neurodegeneration in rat model of Alzheimer’s disease

2018 ◽  
Vol 41 (2) ◽  
pp. 139-150 ◽  
Author(s):  
Chennakesavan Karthick ◽  
Saravanan Nithiyanandan ◽  
Musthafa Mohamed Essa ◽  
Gilles J Guillemin ◽  
Swaminathan K Jayachandran ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Rat Model ◽  
Amyloid Β ◽  
Time Dependent ◽  
Dependent Effect ◽  
Model Of Alzheimer’S Disease ◽  
Time Dependent Effect ◽  
Hippocampal Neurodegeneration

scholarly journals Time-dependent metabolomic profiling of Ketamine drug action reveals hippocampal pathway alterations and biomarker candidates

2014 ◽  
Vol 4 (11) ◽  
pp. e481-e481 ◽  
Author(s):  
K Weckmann ◽  
C Labermaier ◽  
J M Asara ◽  
M B Müller ◽  
C W Turck
Keyword(s):  
Drug Action ◽  
Time Dependent ◽  
Metabolomic Profiling
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