Resistance to fluoroquinolones and treatment failure/short-term relapse of community-acquired urinary tract infections caused by Escherichia coli

2008 ◽  
Vol 57 (3) ◽  
pp. 179-184 ◽  
Author(s):  
Carlo Gagliotti ◽  
Rossella Buttazzi ◽  
Stefano Sforza ◽  
Maria Luisa Moro
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Treatment Failure ◽  
Urinary Tract Infections ◽  
Short Term ◽  
Tract Infections

scholarly journals High Rate of Per Oral Mecillinam Treatment Failure in Community-Acquired Urinary Tract Infections Caused by ESBL-Producing Escherichia coli

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e85889 ◽  
Author(s):  
Arne Søraas ◽  
Arnfinn Sundsfjord ◽  
Silje Bakken Jørgensen ◽  
Knut Liestøl ◽  
Pål A. Jenum
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Treatment Failure ◽  
Urinary Tract Infections ◽  
High Rate ◽  
Tract Infections ◽  
Per Oral

scholarly journals Microbial risk factors for treatment failure of pivmecillinam in community‐acquired urinary tract infections caused by ESBL‐producing Escherichia coli

Apmis ◽  
2020 ◽  
Vol 128 (3) ◽  
pp. 232-241 ◽  
Author(s):  
Heidi Syre ◽  
Marit Andrea Klokkhammer Hetland ◽  
Eva Bernhoff ◽  
Marianne Bollestad ◽  
Nils Grude ◽  
...  
Keyword(s):  
Risk Factors ◽  
Escherichia Coli ◽  
Urinary Tract ◽  
Treatment Failure ◽  
Urinary Tract Infections ◽  
Microbial Risk ◽  
Tract Infections

Treatment duration of pivmecillinam in men, non-pregnant and pregnant women for community-acquired urinary tract infections caused by Escherichia coli: a retrospective Danish cohort study

2019 ◽  
Vol 74 (9) ◽  
pp. 2767-2773 ◽  
Author(s):  
Jonas Bredtoft Boel ◽  
Filip Jansåker ◽  
Frederik Boëtius Hertz ◽  
Katrine Hartung Hansen ◽  
Sara Thønnings ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Cohort Study ◽  
Urinary Tract ◽  
Treatment Failure ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Treatment Duration ◽  
E Coli ◽  
Tract Infections ◽  
Risk Of Treatment

Abstract Objectives To evaluate the importance of treatment duration for therapeutic efficacy of pivmecillinam for community-acquired urinary tract infections (UTIs) caused by Escherichia coli. Methods A retrospective cohort study was conducted between 1 January 2010 and 30 September 2016 in adults with community-acquired E. coli bacteriuria, treated empirically with pivmecillinam. Regimens of 3, 5 and 7 days were compared using clinical treatment failure (i.e. redemption of a new antibiotic or hospitalization due to UTI) within 14 and 30 days as outcome. HR and risk difference with 95% CI were estimated for treatment failure. Results were stratified by age (18–50, 51–70, >70 years) and sex. Results Of the 21864 cases of E. coli UTI that were analysed, 2524 (11.5%) were in men. In 954 cases (4.4%) E. coli produced ESBL and 125 (13.1%) of the cases were in men. The 3 day regimen increased the risk of treatment failure for all groups. The risk differences between the 3 and 5 day regimens were <10% for women, but >10% for men. Comparing the 7 day and 5 day regimens, only women aged >50 years demonstrated an increased risk of treatment failure within 14 days with the 5 day regimen, but not within 30 days. Conclusions With the current data, where data on clinical classification of the E. coli UTI were missing, a 5 day treatment with pivmecillinam at 400 mg three times daily seems to be the rational recommendation for lower UTI in men, pregnant women and women >50 years old. A 3 day regimen seems sufficient for non-pregnant women <50 years old.

scholarly journals Emerging Escherichia coli O25b/ST131 Clone Predicts Treatment Failure in Urinary Tract Infections

2014 ◽  
Vol 60 (4) ◽  
pp. 523-527 ◽  
Author(s):  
F. Can ◽  
O. K. Azap ◽  
C. Seref ◽  
P. Ispir ◽  
H. Arslan ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Treatment Failure ◽  
Urinary Tract Infections ◽  
Tract Infections ◽  
St131 Clone

scholarly journals Treatment Failure in Urinary Tract Infections: A Warning Witness for Virulent Multi-Drug Resistant ESBL- Producing Escherichia coli

2020 ◽  
Vol Volume 13 ◽  
pp. 1839-1850
Author(s):  
Zahra Naziri ◽  
Abdollah Derakhshandeh ◽  
Arash Soltani Borchaloee ◽  
Meisam Poormaleknia ◽  
Negar Azimzadeh
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Treatment Failure ◽  
Urinary Tract Infections ◽  
Drug Resistant ◽  
Tract Infections

Molecular Analysis of Uropathogenic E.coli Isolates from Urinary Tract Infections

2019 ◽  
Vol 19 (3) ◽  
pp. 322-326 ◽  
Author(s):  
Hassan Valadbeigi ◽  
Elham Esmaeeli ◽  
Sobhan Ghafourian ◽  
Abbas Maleki ◽  
Nourkhoda Sadeghifard
Keyword(s):  
Escherichia Coli ◽  
Polymerase Chain Reaction ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Multiplex Polymerase Chain Reaction ◽  
Virulence Genes ◽  
Uropathogenic Escherichia Coli ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Tract Infections

Introduction: The aim of the current study was to investigate the prevalence of virulence genes in uropathogenic Escherichia coli (UPEC) isolates in Ilam. Materials and Methods: For this purpose, a total of 80 UPEC isolates were collected for patients with UTIs during a 6 months period. The multiplex polymerase chain reaction (multiplex PCR) was used to detect the papEF, fimH, iucD, hlyA, fyuA, and ompT genes. Results: The prevalence of fimH, papEF, iucD, fyuA, hlyA, hlyA, and ompT genes were 87.5%, 47.5%, 60%, 67.5%, 27.5%, 47.5% and 71.2%, respectively. Among all of the isolates, 27 profiles were obtained. Conclusion: Our findings demonstrated that the most prevalence was found for fimH, and different distribution of virulence genes suggested different ability of pathogenicity.

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