The effect of skin tension, needle diameter and insertion velocity on the fracture properties of porcine tissue

2021 ◽  
pp. 104660
Author(s):  
T. Irwin ◽  
A. Speirs ◽  
C. Merrett
Keyword(s):  
Fracture Properties ◽  
Porcine Tissue ◽  
Skin Tension ◽  
Needle Diameter

Dose-response Curves in the Fibrin Plate Assay Fibrinolytic Activity of Proteases

1974 ◽  
Vol 32 (02/03) ◽  
pp. 356-365 ◽  
Author(s):  
F Haverkate ◽  
D. W Traas
Keyword(s):  
Dose Response ◽  
Fibrinolytic Activity ◽  
Enzyme Concentration ◽  
Response Curves ◽  
Agar Gel ◽  
Porcine Tissue ◽  
Plate Assay ◽  
Fibrin Plate ◽  
Different Types ◽  
Dose Response Curves

SummaryIn the fibrin plate assay different types of relationships between the dose of applied proteolytic enzyme and the response have been previously reported. This study was undertaken to determine whether a generally valid relationship might exist.Trypsin, chymotrypsin, papain, the plasminogen activator urokinase and all of the microbial proteases investigated, including brinase gave a linear relationship between the logarithm of the enzyme concentration and the diameter of the circular lysed zone. A similar linearity of dose-response curves has frequently been found by investigators who used enzyme plate assays with substrates different from fibrin incorporated in an agar gel. Consequently, it seems that this linearity of dose-response curves is generally valid for the fibrin plate assay as well as for other enzyme plate bioassays.Both human plasmin and porcine tissue activator of plasminogen showed deviations from linearity of semi-logarithmic dose-response curves in the fibrin plate assay.

Separation of Plasminogen Activators from Human Uterine Tissue and a Comparison with Activators from Human Urine and Porcine Tissue

1979 ◽  
Vol 41 (04) ◽  
pp. 718-733 ◽  
Author(s):  
Preben Kok
Keyword(s):  
Plasminogen Activator ◽  
Human Urine ◽  
Gel Filtration ◽  
Ammonium Thiocyanate ◽  
Plasminogen Activators ◽  
Particle Sizes ◽  
Uterine Tissue ◽  
Porcine Tissue ◽  
Major Activity ◽  
Proliferative Phase

SummaryThree types of plasminogen activator could be distinguished in extracts from human uterine tissue. The activators differed in thermostability or in mode of inhibition by EACA.All the extracts contained stable as well as labile activators. The saline extracts were uniformly inhibited by increasing concentrations of EACA. Extracts made with 2 M ammonium thiocyanate were either uniformly inhibited by EACA or showed deflections indicating contamination with an activator, which was inhibited in a biphasic manner. It was possible to distinguish between: (1) An activator, abundantly present in the tissue, which was uniformly inhibited and stable. (2) Another uniformly inhibited activator, which was labile. (3) An activator, inhibited in a biphasic manner, similar to urokinase, which was present in varying amounts in uteri with the endometrium in the proliferative phase.Gel filtration of the uterine extracts showed two major activity peaks corresponding to particle sizes of 60,000 dalton and about 10,000 dalton.Antiserum to purified plasminogen activator, prepared from porcine ovaries, inhibited the activity of the human uterine extracts, but not the activities of human urokinase or urine. Urokinase antiserum in a concentration completely inhibiting human urine or urokinase, inhibited only 10% or less of the activities of human uterine extracts.

Micromechanics Measurements Applied to Integrated Circuit Microelectronics

1997 ◽  
Vol 473 ◽  
Author(s):  
David R. Clarke
Keyword(s):  
Integrated Circuits ◽  
Integrated Circuit ◽  
Fracture Resistance ◽  
Interface Fracture ◽  
New Techniques ◽  
Fracture Properties ◽  
Engineered Structures ◽  
Mechanical And Fracture Properties ◽  
Interconnect Lines ◽  
Metallic Interconnect

ABSTRACTAs in other engineered structures, fracture occasionally occurs in integrated microelectronic circuits. Fracture can take a number of forms including voiding of metallic interconnect lines, decohesion of interfaces, and stress-induced microcracking of thin films. The characteristic feature that distinguishes such fracture phenomena from similar behaviors in other engineered structures is the length scales involved, typically micron and sub-micron. This length scale necessitates new techniques for measuring mechanical and fracture properties. In this work, we describe non-contact optical techniques for probing strains and a microscopic “decohesion” test for measuring interface fracture resistance in integrated circuits.

Comparison of the effects of wet straining and refining on the fracture properties of paper

2002 ◽  
Vol 17 (1) ◽  
pp. 45-49 ◽  
Author(s):  
Gongde Zhang ◽  
Eero Hiltunen ◽  
Jaakko E. Laine ◽  
Hannu Paulapuro ◽  
Heikki Kettunen ◽  
...  
Keyword(s):  
Fracture Properties

scholarly journals Effect of Short Fiber Reinforcements on Fracture Performance of Cement-Based Materials: A Systematic Review Approach

Materials ◽  
2021 ◽  
Vol 14 (7) ◽  
pp. 1745
Author(s):  
Waqas Ahmad ◽  
Mehran Khan ◽  
Piotr Smarzewski
Keyword(s):  
Graphical Representation ◽  
Safety Evaluation ◽  
Short Fiber ◽  
Research Trend ◽  
Scientometric Analysis ◽  
Fiber Reinforced ◽  
Factors Affecting ◽  
Fracture Properties ◽  
Cement Based Materials ◽  
Relevant Publication

Fracture characteristics were used to effectively evaluate the performance of fiber-reinforced cementitious composites. The fracture parameters provided the basis for crack stability analysis, service performance, safety evaluation, and protection. Much research has been carried out in the proposed study field over the previous two decades. Therefore, it was required to analyze the research trend from the available bibliometric data. In this study, the scientometric analysis and science mapping techniques were performed along with a comprehensive discussion to identify the relevant publication field, highly used keywords, most active authors, most cited articles, and regions with largest impact on the field of fracture properties of cement-based materials (CBMs). Furthermore, the characteristic of various fibers such as steel, polymeric, inorganic, and carbon fibers are discussed, and the factors affecting the fracture properties of fiber-reinforced CBMs (FRCBMs) are reviewed. In addition, future gaps are identified. The graphical representation based on the scientometric review could be helpful for research scholars from different countries in developing research cooperation, creating joint ventures, and exchanging innovative technologies and ideas.

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