Relationship between serum uric acid and ischemic stroke in a large type 2 diabetes population in China: A cross-sectional study

2017 ◽  
Vol 376 ◽  
pp. 176-180 ◽  
Author(s):  
Lijun Wang ◽  
Wei Hu ◽  
Dandan Miao ◽  
Qin Zhang ◽  
Chuang Wang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Uric Acid ◽  
Ischemic Stroke ◽  
Serum Uric Acid ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Large Type

scholarly journals Serum uric acid levels in type 2 diabetes mellitus among South Indian Urban Population: A cross sectional study

2020 ◽  
Vol 9 (6) ◽  
pp. 20-24
Author(s):  
Harish Rangareddy ◽  
Venkateshappa C
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Waist Hip Ratio

Background and aim: Hyperuricemia is common in individuals with obesity, metabolic syndrome and type 2 diabetes mellitus. This has been attributed to the hyperinsulinemia due to insulin resistance in T2DM and it’s effect on the renal excretion of uric acid. There have been recent studies depicting that hyperuricemia may independently predict the development of diabetes. However, there are conflicting studies of hypouricemia in T2DM as well which may be due to increased glomerular filtration rate with increased renal clearance of uric acid. In order to add further evidence to the existing database of knowledge about uric acid metabolism in T2DM this study was carried out. Material and Methods: This cross sectional study and the subjects were selected according to inclusion and exclusion criteria. Data recorded included serum uric acid, HbA1c, fasting and post prandial plasma glucose, serum creatinine, fasting lipid profile and waist hip ratio. Results: The mean value of serum uric acid was 5.11±1.2 mg/dL in diabetics and 4.59±1.12 mg/dL in non-diabetics, though within the normal reference range was statistically significant (p=0.029). However, the association of hyperuricemia (serum uric acid >7mg/dL) as a risk factor for diabetes mellitus was not significant (p=1.000). Waist circumference in cases was 94.8 ± 10 cm and in controls it was 86.6 ± 11.6 cm (p<0.001). Waist-hip ratio in diabetics was 1.0 ± 0.11 and in non-diabetics 0.9 ± 0.08 (p<0.001). HbA1c, FBS, PPBS, serum creatinine, waist circumference, waist-hip ratio were significantly increased and HDLc was decreased significantly in diabetes mellitus. Conclusion: Increased serum uric acid, decreased HDLc and increased waist-hip ratio are observed in type 2 diabetes mellitus. Steps should be taken to monitor serum uric acid, lipid profile and anthropometric measurements of diabetics and non-diabetics. Keywords: Uric acid, type 2 Diabetes mellitus

scholarly journals Presenting Features of lschaemic Stroke Patients with Type 2 Diabetes during Hospital Admission at BIRDEM

2012 ◽  
Vol 2 (2) ◽  
pp. 14-18
Author(s):  
Nirmalendu Bikash Bhowmik ◽  
Sufia Jannat ◽  
Md Rashedul Islam ◽  
Rumana Habib ◽  
Aminur Rahman ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Ischemic Stroke ◽  
Cross Sectional Study ◽  
The Body ◽  
Clinical Profile ◽  
Imaging Data ◽  
Sectional Study ◽  
Stroke Patients ◽  
Cross Sectional

Background & objective: Stroke is the third major cause of morbidity and mortality in the world immediately following ischemic heart disease and malignancy. Diabetes mellitus increases risk of ischemic stroke and mortality and morbidity after stroke. This cross sectional study was carried out to observe clinical profile of ischemic stroke in Type 2 diabetic patient. Materials & Methods: This cross-sectional study was done in the Department of Neurology, Bangladesh Institute of Research and Rehabilitation for Diabetes, Endocrine, and Metabolic Disorders (BIRDEM) Hospital, from April to September 2010. A total of 50 ischemic stroke patients with type-2 diabetes were consecutively recruited. Ischemic stroke was confirmed by clinical examination and CT imaging. Data were analysed using SPSS (Statistical Package for Social Sciences) and were presented as mean ± SD and frequencies with corresponding percentages as appropriate. Results: Of the 50 ischemic patients, over one-third (36%) was in their 6th decades of life.  A male preponderance (1.5:1) in the series. Most of the patients presented with weakness on either side of the body (90%) followed by difficulties in speech (80%), altered consciousness (24%) and facial weakness (4%). On examination 76% were conscious and oriented.  Other examination findings were hemiparesis (60%), hemiplegia (30%), dysarthria (72%) and dysphagia (4%).  The major co-morbid condition was hypertension (86%) with mean systolic and diastolic blood pressures being 153 ± 5 and 97 ± 4 mmHg respectively.  On admission 94% had normal pulse  and  40%  abnormal  fundoscopic  examination  in  the  form  of  hypertensive and diabetic retinopathy. Only 2% had carotid bruit. Conclusion: Elderly males are more prone to develop ischemic stroke. Hemiparesis and dysarthria are the major clinical presentation and hypertension might be an important risk factor for ischemic stroke. Further study is recommended to conclusively comment on the clinical features of diabetic ischemic stroke patients and also to compare the clinical profile between diabetic stroke patients. Ibrahim Cardiac Med J 2012; 2(2): 14-18

Large-Scale Cross-Sectional Study of the Problem Areas in Diabetes Survey among Japanese Patients with Type 2 Diabetes Mellitus

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2393-PUB
Author(s):  
KENICHIRO TAKAHASHI ◽  
MINORI SHINODA ◽  
RIKA SAKAMOTO ◽  
JUN SUZUKI ◽  
TADASHI YAMAKAWA ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Large Scale ◽  
Japanese Patients ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetes Survey
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