scholarly journals Serum phospholipid fraction of polyunsaturated fatty acids is the preferred indicator for nutrition and health status in hemodialysis patients

2016 ◽  
Vol 38 ◽  
pp. 18-24 ◽  
Author(s):  
Bruce A. Watkins ◽  
Jeffrey Kim ◽  
Hector Tamez ◽  
Julia Wenger ◽  
Ravi Thadhani ◽  
...  
2012 ◽  
Vol 36 (5) ◽  
pp. 451-458 ◽  
Author(s):  
Allon N. Friedman ◽  
Zhangsheng Yu ◽  
Rebeka Tabbey ◽  
Cheryl Denski ◽  
Hector Tamez ◽  
...  

2019 ◽  
Vol 23 (2) ◽  
pp. 189-197 ◽  
Author(s):  
Julie Ann Kemp ◽  
Marta Esgalhado ◽  
Renata Azevedo Macedo ◽  
Bruna Regis ◽  
Nágila Raquel Teixeira Damasceno ◽  
...  

2015 ◽  
Vol 5 (5) ◽  
pp. 155 ◽  
Author(s):  
Sadako Matsui ◽  
Chizuko Maruyama ◽  
Hiroe Arai ◽  
Sachie Hashimoto ◽  
Tamami Asakusa ◽  
...  

Background: Taurine is an abundant amino acid in human cells, promoting ocular and biliary health, which is also used to treat congestive heart failure, hypertension, and hepatitis. Recently, taurine-enriched energy drinks have become popular with young adults, but the effects of taurine on serum lipids in young adults are unknown.Objective: We studied the influence of oral administration of taurine on serum lipid levels in healthy young women.Methods: Ten healthy young women with a mean body mass index of 20.0kg/m2, apolipoprotein E (apoE) phenotype 3/3 and normal menstrual cycles participated. Each subject was instructed to orally ingest 1g of taurine powder after each meal (3g/day) in addition to their usual diets during one menstrual cycle. Before and at the end of taurine intake, physical measurements and blood collection were performed in the morning after a 12-h fast, and 3-day weighted dietary records were obtained. Concentrations of serum lipids, apolipoproteins, and fatty acids in the serum phospholipid fraction were measured.Results: The subjects showed good compliance with taurine intake and none reported adverse effects during the experimental period. After taurine intake, concentrations of total cholesterol, low density lipoprotein cholesterol (LDL-C), free cholesterol, and apolipoprotein B (apoB) increased (p<0.05), while phospholipids tended to increase (p=0.051). Fatty acids in the serum phospholipid fraction also significantly increased (p<0.05). However, triglyceride, remnant-like particle cholesterol, remnant-like particle triglyceride, apoE, the apolipoprotein A-1 (apoA- 1)/apoB ratio and the LDL-C/apoB ratio were unchanged. Furthermore, body weight was significantly increased (p<0.01), but did not correlate with changes either in serum lipids or nutrient intakes.Conclusion: These results suggest that high taurine intake affects lipoprotein metabolism and increases serum lipids in slightly lean young women.Key Words: Taurine, slightly lean young women, serum lipids, remnant lipoprotein, fatty acids of the serum phospholipid fraction.


1999 ◽  
Vol 97 (2) ◽  
pp. 175-181 ◽  
Author(s):  
Duo LI ◽  
Madeleine BALL ◽  
Melinda BARTLETT ◽  
Andrew SINCLAIR

In the present study we investigated serum lipoprotein(a) [Lp(a)] levels, plasma lipids, the serum phospholipid polyunsaturated fatty acid profile and correlates of serum Lp(a) in healthy free-living female vegetarians (n = 50) and omnivores (n = 24) to assess differences which may have implications for cardiovascular risk. Dietary saturated fat and total plasma cholesterol were significantly lower in the vegetarians compared with omnivores. The mean serum Lp(a) concentration was lower in the vegetarians (171 mg/l) than in the omnivores (247 mg/l). The serum Lp(a) concentration was significantly negatively correlated with carbohydrate intake (as % of energy), and positively correlated with plasma total cholesterol. Compared with the omnivores, the vegetarians had significantly lower concentrations of 20:3,n-6, 20:4,n-6, 22:5,n-6, 20:5,n-3, 22:6,n-3 and total n-6 and n-3 polyunsaturated fatty acids, and a lower n-3/n-6 polyunsaturated fatty acid ratio, in serum phospholipids. Lower concentrations of plasma total cholesterol, serum phospholipid total fatty acids, total saturated fatty acids and arachidonic acid, and a tendency towards a lower serum Lp(a) concentration, in vegetarians may have beneficial effects on cardiovascular disease risk. However, the decreased concentration of serum phospholipid n-3 polyunsaturated fatty acids may potentially promote thrombotic risk. Based on the present data, it would seem appropriate for omnivores to reduce their dietary intake of total fat and saturated fat in order to decrease their plasma cholesterol, and vegetarians should perhaps increase their dietary intake of n-3 polyunsaturated fatty acids, and thus improve the balance of n-3/n-6, in order to reduce any thrombotic tendency that might increase their generally low risk of cardiovascular disease.


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