Assessment of Anxiety and Depression in Adolescents with Primary Dysmenorrhea: A Case-Control Study

Abstract Objectif The aim of this study was to investigate psychiatric comorbidities (depression and anxiety) associated with acne in dermatology in Lomé (Togo). Material and methods We conducted a case-control study between July 2017 and February 2018. Each case was matched to two controls by sex and age (± 5 years). The ECLA grid was used for the clinical evaluation of acne, and the GAD-7 and PHQ-9 questionnaires were used for respective screening of anxiety and depression. Results We recruited, with their consent, 900 subjects including 300 patients and 600 matched to two controls according to sex and age (± 5 years). The mean age of the cases was 23.7±5.7 years and that of the controls was 23.6 ± 6.2 years, with no difference between the two groups (p = 0.9362). The overall severity score for acne according to the ECLA grid ranged from 2 to 28 points. The severity of acne was not correlated with anxiety scores (GAD-7: r = -0.02; p = 0.6724) and depression (PHQ-9: r = 0.11; p = 0.0567). The GAD-7 questionnaire allowed us to note 72 cases of anxiety (24%) among our patients and 37 cases among our controls (6.2%). The mean GAD-7 score in the cases was 6.5±4.9 compared with 2.9±3.8 in the controls (p <0.0001). Similarly, the PHQ-9 questionnaire allowed us to detect 92 cases of depression (30.7%) among our patients and 82 cases of depression among our controls (13.7%). The average of the PHQ 9 score in the cases was 7.2 ± 5.2 versus 4.0 ± 4.7 in the controls (p <0.0001). Conclusion: Depression and anxiety are significantly associated with acne, regardless of severity. It is important to look for them in any patient admitted for acne, for a psychological / psychiatric decision.

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Anxiety sensitivities, anxiety and depression levels, and personality traits of patients with chronic subjective tinnitus: a case-control study

International Journal of Psychiatry in Clinical Practice ◽

10.1080/13651501.2020.1757117 ◽

2020 ◽

Vol 24 (3) ◽

pp. 264-269

Author(s):

Özgül Karaaslan ◽

Yunus Kantekin ◽

Yunus Hacımusalar ◽

Hakan Dağıstan

Keyword(s):

Personality Traits ◽

Case Control Study ◽

Case Control ◽

Anxiety And Depression ◽

Subjective Tinnitus ◽

Control Study

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Panic disorder, anxiety and depression in resistant hypertension - a case–control study

Journal of Hypertension ◽

10.1097/00004872-199715100-00005 ◽

1997 ◽

Vol 15 (10) ◽

pp. 1077-1082 ◽

Cited By ~ 29

Author(s):

Simon J.C. Davies ◽

Parviz Ghahramani ◽

Peter R. Jackson ◽

Julia Hippisley-Cox ◽

Wilfred W. Yeo ◽

...

Keyword(s):

Panic Disorder ◽

Resistant Hypertension ◽

Case Control Study ◽

Case Control ◽

Anxiety And Depression ◽

Control Study

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Assessment of Quality of Life, Anxiety and Depression in Children with Turner Syndrome: A Case-Control Study

Neuroscience International ◽

10.3844/amjnsp.2015.8.12 ◽

2015 ◽

Vol 6 (1) ◽

pp. 8-12 ◽

Cited By ~ 1

Author(s):

Khaled A. Abdel Baseer ◽

Abdulrahman Abdullah Al-Atram ◽

Khaled Saad ◽

Ahmed M. Ali ◽

Amira A. El-Houfey

Keyword(s):

Quality Of Life ◽

Turner Syndrome ◽

Case Control Study ◽

Case Control ◽

Anxiety And Depression ◽

Control Study

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The relationship between alopecia areata and alexithymia, anxiety and depression: A case-control study

Indian Journal of Dermatology ◽

10.4103/0019-5154.135525 ◽

2014 ◽

Vol 59 (4) ◽

pp. 421 ◽

Cited By ~ 18

Author(s):

Rim Sellami ◽

J Masmoudi ◽

U Ouali ◽

L Mnif ◽

M Amouri ◽

...

Keyword(s):

Alopecia Areata ◽

Case Control Study ◽

Case Control ◽

Anxiety And Depression ◽

The Relationship ◽

Control Study

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Anxiety and depression are risk factors for recurrent pregnancy loss: A nested case-control study

10.21203/rs.3.rs-59392/v2 ◽

2020 ◽

Author(s):

Yanxia Wang ◽

Zhaoyan Meng ◽

Jianyin Pei ◽

Liu Qian ◽

Baohong Mao ◽

...

Keyword(s):

Pregnancy Loss ◽

Recurrent Pregnancy Loss ◽

Case Control Study ◽

Severe Depression ◽

Case Control ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Nested Case Control ◽

Severe Anxiety ◽

Control Study

Abstract Background: To evaluate the interaction of depression and anxiety with the development of recurrent pregnancy loss (RPL).Methods: A nested case–control study involving 2,558 participants was conducted with data from the prospective Miscarriage Woman Cohort study between 2017 and 2019 in the province of Gansu, China. The questionnaire data, self-rating anxiety scale and self-rating depression scale were collected after each participant’s first miscarriage. Information on RPL outcomes was obtained from the medical records within the subsequent two years. All patients diagosed RPL were recruited as cases whilst a randomly selected group of women with only one miscarriage in the past were recruited as controls. The logistic regression and the interaction effects between anxiety and depression and RPL were analysed.Results: The prevalence of anxiety (n=325, 28.7% vs. n=278, 19.5%) and depression symptoms (n=550, 48.6% vs. n=589, 41.3%) for the 1,132 RPL cases were higher than 1,426 non-RPL controls (P< 0.001). After adjusting for possible confounding variables, the odds ratio (OR) value, reflecting the multiplicative interaction, was 1.91 (95% CI: 1.50–2.44, P<0.001) for cases with both anxiety and depression symptoms compared with the non-RPL group. The relative excess risk of interaction value, reflecting the additive interaction between anxiety and depression to RPL was 1.15 (95% CI: 0.32–4.21). Moreover, the adjusted OR for RPL cases with mild anxiety and severe depression was 2.77 (95% CI:1.07-44.14, P<0.001) , for RPL cases with severe anxiety and mild depression was 4.23 (95% CI: 1.01–22.21, P<0.001), for RPL cases with severe anxiety and moderate depression was 4.34 (95% CI: 1.03–21.28, P<0.001) and for RPL cases with severe anxiety and severe depression was 5.95 (95% CI: 1.09–45.09, P<0.05).Conclusions: Either depression or anxiety alone could increase the risk of subsequent RPL. Anxiety and depression had a synergistic effect after the first miscarriage which increased the development of subsequent RPL disease.

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Association of Psoriasis With Anxiety and Depression: A Case–Control Study in Chinese Patients

Frontiers in Medicine ◽

10.3389/fmed.2021.771645 ◽

2021 ◽

Vol 8 ◽

Author(s):

Danrong Jing ◽

Hui Xiao ◽

Minxue Shen ◽

Xiang Chen ◽

Xi Han ◽

...

Keyword(s):

Subgroup Analysis ◽

Psoriasis Vulgaris ◽

Case Control Study ◽

Clinical Information ◽

Case Control ◽

Chinese Patients ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Healthy Controls ◽

Control Study

Background: Patients with psoriasis are prone to suffer from anxiety and depression during their lifetime. This study aimed to investigate the association of psoriasis with anxiety and depression in Chinese patients.Methods: A case-control study in Chinese patients with psoriasis vulgaris and healthy controls was conducted. Clinical information based on patient-reported, clinical information, and reliable structured questionnaires were collected. Multivariable logistic regression was used to investigate the associations, in terms of adjusted odds ratios (AORs).Results: We continuously selected 1,571 patients who were firstly diagnosed with psoriasis vulgaris, and 1,571 healthy controls, matched by age and sex. The risk of depression in the psoriasis vulgaris group was higher than that in the healthy controls (AOR = 1.30, P = 0.047), while no differences were found in the risk of anxiety between the two groups (AOR = 1.18, P = 0.381). Subgroup analysis by disease onsets showed that late-onset psoriasis (LOP) was significantly associated with a higher risk of anxiety (AOR = 1.47, P = 0.033) and depression symptoms (AOR = 1.85, P = 0.012) but not with early-onset psoriasis (EOP). Subgroup analysis by disease severity indicated that no difference was observed in the associations of mild psoriasis vulgaris, moderate-to-severe psoriasis vulgaris with anxiety and depression.Conclusion: Patients with psoriasis vulgaris were more likely to develop depression compared with the general population. LOP patients were positively associated with anxiety and depression. We believe the screening of emotional disorders should be included in the daily management of psoriasis patients.

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