(156) Pain catastrophizing moderates the relationship between self-report and objective measures of sleep continuity and clinical pain and central sensitization in women with TMD

2016 ◽  
Vol 17 (4) ◽  
pp. S14-S15 ◽  
Author(s):  
S. Lerman Zohar ◽  
L. Buenaver ◽  
M. Redding ◽  
J. Richards ◽  
C. Campbell ◽  
...  
2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 569-569
Author(s):  
Shauna McManus ◽  
Jolinta Y Lin ◽  
Manali A. Bhave ◽  
Gabrielle Brown ◽  
India Green ◽  
...  

569 Background: Patient-reported outcomes (PROs) of cosmesis after breast-conserving therapy (BCT) are increasingly emphasized as meaningful treatment endpoints but little is known about the relationship between objective measures, mood, and PROs following radiation (XRT). We hypothesized that pre-XRT depression, assessed by Inventory of Depressive Symptomatology Self-Report (IDS-SR), would influence PROs of breast cosmesis 1-year post-XRT independent of objective measures of breast asymmetry. Methods: 98 women were enrolled on two prospective longitudinal studies of breast cosmesis. Percentage breast retraction assessment (pBRA) was used as an objective measure of breast asymmetry pre- and 1 year post-XRT. At the same time points, pBRA was measured and compared with two different PRO ratings of cosmetic outcome (0-10 scale): 1) happiness with cosmesis and 2) perceived differences in treated vs. untreated breast. We performed univariate and multivariate analysis to evaluate the relationship between PROs, pBRA, IDS-SR scores, clinical, tumor, and treatment characteristics. Results: Among subjects, 50% were African American. Mean age was 56.45 years. At 1 year, 65.3% of patients were happy with their cosmetic outcome (Score > 8) although 59.5% noted moderate to severe differences in the treated vs. untreated breast (Score < 6). Mean pBRA increased from 7.20 (SD 3.88) pre-XRT to 9.69 (SD 6.22) confirming more breast asymmetry 1-year post-XRT. Prior to XRT, 23% of patients had moderate-to-severe depression (IDS-SR scores > 26). In multivariate analyses, 1 year PROs of happiness with cosmetic outcome did not correlate with pBRA (p = 0.3) but were strongly correlated with pre and post-XRT depression (all p < 0.05). Patients were more likely to perceive differences in breast texture or asymmetry (i.e. lower PRO ratings of asymmetry) if they had higher pBRA measurements at 1 year (all p = 0.004). Neither pre- nor post- XRT depression were associated with specific PRO ratings of breast asymmetry in multivariate analysis. Conclusions: Our study suggests that PROs may not always reflect the effects of cancer treatment. For patients treated with BCT, baseline depression strongly influenced patient reported happiness with overall cosmetic outcome 1 year post-XRT. Perceived differences in the treated vs. untreated breast correlated with objective measures of breast asymmetry. Our data suggests that this PRO may be more indicative of treatment-related toxicities than patient ratings of overall satisfaction and happiness with cosmetic outcome. Clinical trial information: NCT03167359 .


2012 ◽  
Vol 17 (5) ◽  
pp. 335-340 ◽  
Author(s):  
Whitney Scott ◽  
Michael Sullivan

BACKGROUND: Numerous investigations report that depressive symptoms frequently coexist with persistent pain. However, evidence suggests that symptoms of depression are not an inevitable consequence of pain. Diathesis-stress formulations suggest that psychological factors interact with the stress of pain to heighten the risk of depressive symptoms. Perceptions of injustice have recently emerged as a factor that may interact with the stress of pain to increase depressive symptoms.OBJECTIVES: The purpose of the present study was to examine whether perceived injustice moderates the relationship between pain and depressive symptoms.METHODS: A total of 107 individuals with persistent musculoskeletal pain completed self-report measures of pain severity, depressive symptoms, perceived injustice and catastrophizing.RESULTS: A hierarchical regression analysis revealed that the interaction between pain severity and perceived injustice uniquely contributed an additional 6% of the variance to the prediction of depressive symptoms, beyond the main effects of these variables. Post hoc probing indicated that pain was significantly related to depressive symptoms at high, but not low levels of perceived injustice. This finding remained statistically significant even when controlling for pain catastrophizing.CONCLUSIONS: The results suggest that perceived injustice augments the relationship between pain severity and depressive symptoms. The inclusion of techniques specifically targeting perceptions of injustice may enhance the effectiveness of interventions aimed at reducing symptoms of depression for individuals presenting with strong perceptions of injustice.


2016 ◽  
Vol 17 (4) ◽  
pp. S56 ◽  
Author(s):  
E. Burton ◽  
C. Campbell ◽  
M. Robinson ◽  
S. Bounds ◽  
L. Buenaver ◽  
...  

2005 ◽  
Vol 7 (4) ◽  
pp. 137-142 ◽  
Author(s):  
Erin M. Snook ◽  
Mina C. Mojtahedi ◽  
Ellen M. Evans ◽  
Edward McAuley ◽  
Robert W. Motl

Individuals with multiple sclerosis (MS) engage in less physical activity than the general population. This level of inactivity may increase a person's risk of being overweight and obese. The relationship between physical activity and body composition is examined among 34 ambulatory adults with a definite diagnosis of MS. Participants wore pedometers and accelerometers, objective measures of physical activity, for 7 days; completed a self-report measure of physical activity; and underwent various measurements of body composition, including body mass index (BMI), waist circumference, and relative body fat by dual energy X-ray absorptiometry (DXA). Statistically significant negative correlations were found between physical activity levels and measures of body fatness, and the correlations were strong between the objective measures of physical activity and DXA measures of body composition. The correlations were moderate between the self-report measure of physical activity and less precise measures of body composition. Our findings suggest that inactivity plays an important role in body fatness among people with MS, and subjective measures of physical activity and less precise measures of body fatness, such as BMI, may underestimate the strength of the relationship between physical activity and risk for obesity in the MS population.


Pain Medicine ◽  
2019 ◽  
Vol 20 (10) ◽  
pp. 1942-1947 ◽  
Author(s):  
Andrew S Huhn ◽  
D Andrew Tompkins ◽  
Claudia M Campbell ◽  
Kelly E Dunn

Abstract Objective Individuals with chronic pain who misuse prescription opioids are at high risk for developing opioid use disorder and/or succumbing to opioid overdose. The current study conducted a survey to evaluate sex-based differences in pain catastrophizing, opioid withdrawal, and current pain in persons with co-occurring chronic pain and opioid misuse. We hypothesized that women with chronic pain who misused prescription opioids would self-report higher pain ratings compared with men and that the relationship between pain catastrophizing and self-reported current pain would be moderated by symptoms of opioid withdrawal in women only. Design Survey assessment of the relationship between pain and opioid misuse. Setting Online via Amazon Mechanical Turk. Participants Persons with ongoing chronic pain who also misused prescription opioids on one or more days in the last 30 days were eligible (N = 181). Methods Participants completed demographic and standardized assessments including the Brief Pain Inventory (BPI), Pain Catastrophizing Scale (PCS), and Subjective Opiate Withdrawal Scale (SOWS). Results Women reported higher levels of current (P < 0.001), average (P < 0.001), and worst (P = .002) pain in the last 24 hours compared with men. Women also endorsed higher scores on the PCS (P = 0.006) and marginally higher past-30-day SOWS ratings (P = 0.068) compared with men. SOWS ratings moderated the relationship between PCS and BPI Worst Pain in women (ΔR2 < 0.127, ΔF(1, 78) = 12.39, P = 0.001), but not in men (ΔR2 < 0.000, ΔF(1, 98) = 0.003, P = 0.954). Conclusions These data suggest a strong relationship between opioid withdrawal, pain catastrophizing, and the experience of pain in women with chronic pain who misuse opioids.


2019 ◽  
Author(s):  
Arianna Kassi Paricos

This study aims to explore the relationship between social anxiety and Theory of Mind (ToM) ability. Findings are evaluated in the context of theoretical models (Clark &amp; Wells, 1995; Heimberg et al., 2010), to aid improvement of the understanding of social anxiety disorder (SAD). Two hypotheses are proposed: (1) social anxiety will negatively associate with self-report and objective measures of ToM ability; (2) objective and self-report measures of ToM will be positively associated. Literature assessing the relationship between social anxiety and ToM has not produced consistent results and has exclusively focused on ToM decoding and reasoning ability. This study is the first to explore the relationship between social anxiety, cognitive and affective ToM ability, and self-reported ToM ability. A correlational study was conducted (36 participants), comparing Social Interaction Anxiety Scale scores (SIAS; Mattick &amp; Clarke, 1998) for social anxiety levels; Interpersonal Reactivity Index (IRI) perspective-taking subscale scores for self-reported ToM ability (Davis, 1980); error rate (in millimeters) on the Paper and Pencil Sandbox Task (Coburn, Bernstein, &amp; Begeer, 2015) for cognitive ToM ability; and reaction times on the Yoni Task (Shamay-Tsoory &amp; Aharon-Peretz, 2007) for cognitive and affective ToM ability. Contrary to expectations, no significant relationships were found between any of the measures. The results prompt re-thinking regarding the mechanisms of SAD and offer insight into the complexity of the relationship between social anxiety and ToM ability. However, the implications can only be inferred within the context of the study limitations, these are discussed alongside recommendations for future research.


2017 ◽  
Vol 17 (1) ◽  
pp. 118-125 ◽  
Author(s):  
Johan K.P. Carstens ◽  
Katja Boersma ◽  
Martien G.S. Schrooten ◽  
Steven J. Linton

AbstractBackgroundIncreasing recall of instructions and advice in a pain consultation is important, since it is a prerequisite for adherence to treatment recommendations. However, interference due to pain-related distress may result in poor recall. Whereas there are some indications that recall can be increased by empathic communication that reduces interference, this interesting possibility remains largely untested experimentally.The current experiment aimed at studying effects of empathic communication, and more specifically validation, on recall during a pain test and possible mediators and moderators of this effect.MethodParticipants received either validating (N = 25) or invalidating responses (N = 25) from the experimenter during a pain provoking task, followed by self-report measures of interference (affect, situational pain catastrophizing) and recall (accurate and false memories of words).ResultsAs expected, the validated group exhibited higher accurate recall and less false memories following the pain test as compared to the invalidated group. This was partly due to the effect of interference being counteracted by moderating the relationship between pain catastrophizing and recall.ConclusionThese novel results suggest that validating communication can counteract interference due to pain catastrophizing on recall, at least in a controlled experimental setting.ImplicationsGood communication by health professionals is of utmost importance for adherence to pain management. The current results expand our knowledge on the effects of pain communication by establishing and explaining a clear link between empathic communication and recall, highlighting the role of pain catastrophizing.


PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250547
Author(s):  
David Ferrera ◽  
Francisco Mercado ◽  
Irene Peláez ◽  
David Martínez-Iñigo ◽  
Roberto Fernandes-Magalhaes ◽  
...  

Previous research has shown a consistent association among genetic factors, psychological symptoms and pain associated with fibromyalgia. However, how these symptoms interact to moderate genetic factors in fibromyalgia has rarely been studied to date. The present research investigates whether psychological symptoms can moderate the effects of catechol-O-methyltransferase on pain and fatigue. A total of 108 women diagnosed with fibromyalgia and 77 healthy control participants took part in the study. Pain, fatigue, and psychological symptoms (anxiety, depression, pain catastrophizing, fear of pain and fear of movement) were measured by self-report questionnaires. Two types of statistical analyses were performed; the first was undertaken to explore the influences of COMT genotypes on clinical symptoms by comparing patients with fibromyalgia and healthy controls. In the second analysis, moderation analyses to explore the role of psychological symptoms as potential factors that moderate the relationship between pain/fatigue and COMT genotypes were performed. The main results indicated that patients carrying the Met/Met genotype reported significantly higher levels of fatigue than heterozygote carriers (i.e., Met/Val genotype) and higher levels of fatigue, but not significantly different, than Val homozygote carriers. Among patients with fibromyalgia carrying methionine alleles (i.e., Met/Met + Met/Val carriers), only those who scored high on medical fear of pain, experienced an intensified feeling of fatigue. Thus, the present research suggests that fear of pain, as a psychological symptom frequently described in fibromyalgia may act as a moderating factor in the relationship between the Met allele of the COMT gene and the increase or decrease in self-reported fatigue. Although further research with wider patient samples is needed to confirm the present findings, these results point out that the use of psychological interventions focused on affective symptomatology might be a useful tool to reduce the severity of fibromyalgia.


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